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NBDE Part II > PHARM GENERIC PREFIX/ROOT/SUFFIX > Flashcards

PHARM GENERIC PREFIX/ROOT/SUFFIX Flashcards

1
Q

Prefix/Root/Suffix: -AFIL eg: SIL-DEN-A-FIL (very popular brand name)

A

phospho-diesterase (PDE) inhibitor aka Viagra (for erectile dysfunction)

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2
Q

Prefix/Root/Suffix: -ASONE

A

corticosteroid

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3
Q

Prefix/Root/Suffix: -BICIN eg: Dox-o-rubicin

A

antineoplastic; cytotoxic agent

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4
Q

Prefix/Root/Suffix: -BITAL

A

barbituate (sedative)

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5
Q

Prefix/Root/Suffix: -CAINE

A

local anesthetic

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6
Q

Prefix/Root/Suffix: CEF- or CEPH- (mech of action)

A

cephalosporin antibiotic (B-lactam)

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7
Q

Prefix/Root/Suffix: -CILLIN (mech of action)

A

penicillin antibiotic (B-lactam)

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8
Q

Prefix/Root/Suffix: CORT

A

corticosteriod

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9
Q

Prefix/Root/Suffix: -CYCLINE (mech of action)

A

tetracycline antibiotic (30S unit of bacteria ribosomes)

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10
Q

Prefix/Root/Suffix: -DAZOLE (mech of action)

A

anTHELminTIC (anti-parasitic/anti-HELMINTHS); antibiotic, antibacterial (inhibits nucleic acid synthesis in ANerobic organisms)

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11
Q

Prefix/Root/Suffix: -DIPINE

A

Calcium Channel Blocker

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12
Q

Prefix/Root/Suffix: -DRONATE

A

bisphosphonate; bone resorption inhibitor

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13
Q

Prefix/Root/Suffix: -EPRAZOLE, -OPRAZOLE

A

Proton Pump Inhibitor (PPI)

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14
Q

Prefix/Root/Suffix: -FENAC eg Di-Clo-fenac

A

NSAID (acetic acid deriviative like indomethacin and ketolorac)

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15
Q

Prefix/Root/Suffix: -FLOXACIN (mech of action)

A

quinolone antibiotic (topoisomerase inhibitor, leading to DNA fragmentation)

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16
Q

Prefix/Root/Suffix: -GLIPTIN (mech of action) eg. Sit-a-gliptin (Januvia)

A

antidiabetic; inhibitor of the DPP-4 enzyme

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17
Q

Prefix/Root/Suffix: -GLITAZONE (mech of action) eg. Rosi-glitazone (Avandia)

A

antidiabetic; thiazolidine-dione (causes retained fatty acids and thus more use of glucose for cellular fuel)

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18
Q

Prefix/Root/Suffix: -IRAMINE eg: Brom-phen-iramine (Dimetapp)

A

antihistamine

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19
Q

Prefix/Root/Suffix: -LAMIDE (3 indications?) eg.acet-azol-amide (Diamox)

A

Carbonic anhydrase inhibitor (glaucoma, diuretic, epilepsy)

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20
Q

Prefix/Root/Suffix: -MAB

A

Monoclonal AntiBody

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21
Q

Prefix/Root/Suffix: -MUSTINE eg Ura-mustine (uracil mustard)

A

alkylating agent (antineoplastic)

22
Q

Prefix/Root/Suffix: -MYCIN (mech of action)

A

antibiotic; antibacterial (macrolide-protein synthesis inhibitor on 50S of ribosome)

23
Q

Prefix/Root/Suffix: -NACIN (1 indication?) eg. Sol-if-en-acin (Vesicare)

A

muscarinic agoinist (anticholenergic) (overactive bladder)

24
Q

Prefix/Root/Suffix: -NAZOLE (mech of action)

A

antifungal (inhibits ergosterol produciton and thus breaks down fungal cytoplasmic membrane)

25
Q

Prefix/Root/Suffix: -OLOL

A

beta-blocker

26
Q

Prefix/Root/Suffix: -OLONE (2 types)

A

1.cortico steriod 2.anabolic steroid

27
Q

Prefix/Root/Suffix: PARIN or -PARIN eg. heparin

A

antithrombotic, anticoagulant (blood thinner)

28
Q

Prefix/Root/Suffix: -PHYLLINE (3 indications?) eg Theo-phylline found in tea, cacao, yerba mate

A

Xanthine derivative (bronchodilator) (asthma, COPD, anaphylaxis)

29
Q

Prefix/Root/Suffix: -PRAMINE (mech of action) eg. Clom-i-pramine (Ana-fran-il)

A

Tricyclic Antidepressant (TCA) (mostly act as SNRI’s-seratonin-norepi reuptake inhibitors)

30
Q

Prefix/Root/Suffix: PRED or PRED-

A

corticosteroid

31
Q

Prefix/Root/Suffix: -PRIL

A

ACE inhibitor

32
Q

Prefix/Root/Suffix: -PROFEN

A

NSAID

33
Q

Prefix/Root/Suffix: -RIDONE (3 indications?) eg. Ris-per-idone (Risperdal)

A

Atypical Antipsychotic (schizophrenia, bipolar disorder, autism)

34
Q

Prefix/Root/Suffix: -SARTAN

A

Angiotensin II receptor antagoinist (ARB)

35
Q

Prefix/Root/Suffix: -SEMIDE

A

loop diuretic (water pill-like THIAZIDE)

36
Q

Prefix/Root/Suffix: -SETRON (indication) eg. On-dan-setron (Zofran)

A

serotonin 5-HT3 receptor agonist/ antiemetic (post op or during chemo antiemetic)

37
Q

Prefix/Root/Suffix: -STATIN (mech of action)

A

HMG-CoA reductase inhibitor (inhibits the production of MEVALONATE thus inhibiting cholesterol production)

38
Q

Prefix/Root/Suffix: SULFA- (mech of action)

A

antibiotic, anti-infective, anti-inflammatory (blocks bacterial folic acid synthesis)

39
Q

Prefix/Root/Suffix: -TADINE (2) eg: Lor-at-adine (very popular brand name)

A

antihistamine AND anti-viral (anti-influenza A)..Lor-at-adine aka CLARITIN

40
Q

Prefix/Root/Suffix: -TEROL eg. albuterol

A

beta agonist; bronchodilator

41
Q

Prefix/Root/Suffix: -THIAZIDE

A

thiazide diuretic (water pill-like SEMIDE)

42
Q

Prefix/Root/Suffix: -TINIB eg. Cabo-zan-tinib (Cabometyx)

A

antineoplastic (kinase inhibitor)

43
Q

Prefix/Root/Suffix: -TREL eg. levo-nor-gestrel (very popular brand name)

A

female hormone levonorgestrel=Plan B (progestin)

44
Q

Prefix/Root/Suffix: TRETIN-, TRETIN, OR -TRETIN eg. Alli-tretin-oin (Panretin)

A

Retinoid, dermatologic, form of Vitamin A

45
Q

Prefix/Root/Suffix: -TRIPTAN (mech of action) eg. Zol-mi-triptan (Zomig)

A

Antimigrane, selective 5-HT receptor agonist

46
Q

Prefix/Root/Suffix: -TYLINE (mech of action) eg. Ami-trip-tyline (Elavil)

A

Tricyclic Antidepressant (mostly act as SNRI’s-seratonin-norepi reuptake inhibitors)

47
Q

Prefix/Root/Suffix: VIR or -VIR (5 different types of indication)

A

1.anti-HIV 2.anti-hepatitis 3.anti-herpes 4.anti-CMV 5.anti-flu

48
Q

Prefix/Root/Suffix: -VUDINE (2 indications?) eg Zido-vudine (AZT)

A

antiviral, nucleoside analogue (1.HIV 2.Hep B)

49
Q

Prefix/Root/Suffix: -ZEPAM (mech of action)

A

Benzodiazapine (increase GABA efficiency and therefore DECREASE excitability of neurons)

50
Q

Prefix/Root/Suffix: -ZODONE eg. Traz-o-done (Desyrel)

A

antidepressant

51
Q

Prefix/Root/Suffix: -ZOLAM (mech of action) eg medazolam (Versed)

A

Benzodiazapine (increase GABA efficiency and therefore DECREASE excitability of neurons)

52
Q

Prefix/Root/Suffix: -ZOSIN (2 indications?) eg tamulosin (popular brand name)

A

alpha blocker…HTN and BPH..Flomax

NBDE Part II (14 decks)

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