Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

NBDE Part II > PHARM GENERIC PREFIX/ROOT/SUFFIX > Flashcards

PHARM GENERIC PREFIX/ROOT/SUFFIX Flashcards

1
Q

Prefix/Root/Suffix: -AFIL eg: SIL-DEN-A-FIL (very popular brand name)

A

phospho-diesterase (PDE) inhibitor aka Viagra (for erectile dysfunction)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Prefix/Root/Suffix: -ASONE

A

corticosteroid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Prefix/Root/Suffix: -BICIN eg: Dox-o-rubicin

A

antineoplastic; cytotoxic agent

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Prefix/Root/Suffix: -BITAL

A

barbituate (sedative)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Prefix/Root/Suffix: -CAINE

A

local anesthetic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Prefix/Root/Suffix: CEF- or CEPH- (mech of action)

A

cephalosporin antibiotic (B-lactam)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Prefix/Root/Suffix: -CILLIN (mech of action)

A

penicillin antibiotic (B-lactam)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Prefix/Root/Suffix: CORT

A

corticosteriod

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Prefix/Root/Suffix: -CYCLINE (mech of action)

A

tetracycline antibiotic (30S unit of bacteria ribosomes)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Prefix/Root/Suffix: -DAZOLE (mech of action)

A

anTHELminTIC (anti-parasitic/anti-HELMINTHS); antibiotic, antibacterial (inhibits nucleic acid synthesis in ANerobic organisms)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Prefix/Root/Suffix: -DIPINE

A

Calcium Channel Blocker

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Prefix/Root/Suffix: -DRONATE

A

bisphosphonate; bone resorption inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Prefix/Root/Suffix: -EPRAZOLE, -OPRAZOLE

A

Proton Pump Inhibitor (PPI)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Prefix/Root/Suffix: -FENAC eg Di-Clo-fenac

A

NSAID (acetic acid deriviative like indomethacin and ketolorac)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Prefix/Root/Suffix: -FLOXACIN (mech of action)

A

quinolone antibiotic (topoisomerase inhibitor, leading to DNA fragmentation)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Prefix/Root/Suffix: -GLIPTIN (mech of action) eg. Sit-a-gliptin (Januvia)

A

antidiabetic; inhibitor of the DPP-4 enzyme

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Prefix/Root/Suffix: -GLITAZONE (mech of action) eg. Rosi-glitazone (Avandia)

A

antidiabetic; thiazolidine-dione (causes retained fatty acids and thus more use of glucose for cellular fuel)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Prefix/Root/Suffix: -IRAMINE eg: Brom-phen-iramine (Dimetapp)

A

antihistamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Prefix/Root/Suffix: -LAMIDE (3 indications?) eg.acet-azol-amide (Diamox)

A

Carbonic anhydrase inhibitor (glaucoma, diuretic, epilepsy)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Prefix/Root/Suffix: -MAB

A

Monoclonal AntiBody

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Prefix/Root/Suffix: -MUSTINE eg Ura-mustine (uracil mustard)

A

alkylating agent (antineoplastic)

22
Q

Prefix/Root/Suffix: -MYCIN (mech of action)

A

antibiotic; antibacterial (macrolide-protein synthesis inhibitor on 50S of ribosome)

23
Q

Prefix/Root/Suffix: -NACIN (1 indication?) eg. Sol-if-en-acin (Vesicare)

A

muscarinic agoinist (anticholenergic) (overactive bladder)

24
Q

Prefix/Root/Suffix: -NAZOLE (mech of action)

A

antifungal (inhibits ergosterol produciton and thus breaks down fungal cytoplasmic membrane)

25
Prefix/Root/Suffix: -OLOL
beta-blocker
26
Prefix/Root/Suffix: -OLONE (2 types)
1.cortico steriod 2.anabolic steroid
27
Prefix/Root/Suffix: PARIN or -PARIN eg. heparin
antithrombotic, anticoagulant (blood thinner)
28
Prefix/Root/Suffix: -PHYLLINE (3 indications?) eg Theo-phylline found in tea, cacao, yerba mate
Xanthine derivative (bronchodilator) (asthma, COPD, anaphylaxis)
29
Prefix/Root/Suffix: -PRAMINE (mech of action) eg. Clom-i-pramine (Ana-fran-il)
Tricyclic Antidepressant (TCA) (mostly act as SNRI's-seratonin-norepi reuptake inhibitors)
30
Prefix/Root/Suffix: PRED or PRED-
corticosteroid
31
Prefix/Root/Suffix: -PRIL
ACE inhibitor
32
Prefix/Root/Suffix: -PROFEN
NSAID
33
Prefix/Root/Suffix: -RIDONE (3 indications?) eg. Ris-per-idone (Risperdal)
Atypical Antipsychotic (schizophrenia, bipolar disorder, autism)
34
Prefix/Root/Suffix: -SARTAN
Angiotensin II receptor antagoinist (ARB)
35
Prefix/Root/Suffix: -SEMIDE
loop diuretic (water pill-like THIAZIDE)
36
Prefix/Root/Suffix: -SETRON (indication) eg. On-dan-setron (Zofran)
serotonin 5-HT3 receptor agonist/ antiemetic (post op or during chemo antiemetic)
37
Prefix/Root/Suffix: -STATIN (mech of action)
HMG-CoA reductase inhibitor (inhibits the production of MEVALONATE thus inhibiting cholesterol production)
38
Prefix/Root/Suffix: SULFA- (mech of action)
antibiotic, anti-infective, anti-inflammatory (blocks bacterial folic acid synthesis)
39
Prefix/Root/Suffix: -TADINE (2) eg: Lor-at-adine (very popular brand name)
antihistamine AND anti-viral (anti-influenza A)..Lor-at-adine aka CLARITIN
40
Prefix/Root/Suffix: -TEROL eg. albuterol
beta agonist; bronchodilator
41
Prefix/Root/Suffix: -THIAZIDE
thiazide diuretic (water pill-like SEMIDE)
42
Prefix/Root/Suffix: -TINIB eg. Cabo-zan-tinib (Cabometyx)
antineoplastic (kinase inhibitor)
43
Prefix/Root/Suffix: -TREL eg. levo-nor-gestrel (very popular brand name)
female hormone levonorgestrel=Plan B (progestin)
44
Prefix/Root/Suffix: TRETIN-, TRETIN, OR -TRETIN eg. Alli-tretin-oin (Panretin)
Retinoid, dermatologic, form of Vitamin A
45
Prefix/Root/Suffix: -TRIPTAN (mech of action) eg. Zol-mi-triptan (Zomig)
Antimigrane, selective 5-HT receptor agonist
46
Prefix/Root/Suffix: -TYLINE (mech of action) eg. Ami-trip-tyline (Elavil)
Tricyclic Antidepressant (mostly act as SNRI's-seratonin-norepi reuptake inhibitors)
47
Prefix/Root/Suffix: VIR or -VIR (5 different types of indication)
1.anti-HIV 2.anti-hepatitis 3.anti-herpes 4.anti-CMV 5.anti-flu
48
Prefix/Root/Suffix: -VUDINE (2 indications?) eg Zido-vudine (AZT)
antiviral, nucleoside analogue (1.HIV 2.Hep B)
49
Prefix/Root/Suffix: -ZEPAM (mech of action)
Benzodiazapine (increase GABA efficiency and therefore DECREASE excitability of neurons)
50
Prefix/Root/Suffix: -ZODONE eg. Traz-o-done (Desyrel)
antidepressant
51
Prefix/Root/Suffix: -ZOLAM (mech of action) eg medazolam (Versed)
Benzodiazapine (increase GABA efficiency and therefore DECREASE excitability of neurons)
52
Prefix/Root/Suffix: -ZOSIN (2 indications?) eg tamulosin (popular brand name)
alpha blocker...HTN and BPH..Flomax

NBDE Part II (14 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions