ORAL PATH REVIEW POWERPOINT 2 Flashcards

1
Q

Taumatic Ulcer: anything lasting for more than _______ should be biopsied

A

2 weeks

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2
Q

NAME THAT CONDITION: unknown cause and not infectious; found on NON-KERATINIZED tissue; 3 forms are minor, major, and herpetiform; red halo surrounding central yellow/ white area

A

Apthous Stomatitis

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3
Q

What are the three forms of Apthous Stomatitis?

A

Minor, Major, Herpetiform

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4
Q

What is the treatment for Apthous Stomatitis?

A

Corticosteroids

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5
Q

________ herpes can be found on BOTH keratinized and non-keratinized tissue

A

PRIMARY

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6
Q

Which type of herpes outbreak is associated with fever, malaze, and lymphadenopathy (but may be subclinical)?

A

Primary

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7
Q

Which type of herpes outbreak is typically asymptomatic?

A

recurrent

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8
Q

_______ herpes found on keratinized tissue only

A

RECURRENT

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9
Q

Name that type of herpes: prodrome usually proceeds

A

recurrent

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10
Q

Name that type of herpes: found in the same location

A

recurrent

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11
Q

How long do you have to tx Primary Herpes?

A

within 3 days

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12
Q

What can you treat Primary Herpes? What is the tx regimen? (for children and adults)

A

A-CYCLOVIR (A is primary) suspension rinse and swallow 5x/day. Children 15mg/kg. Adults 200mg

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13
Q

What can you treat recurrent herpes with? What is the tx regimen?

A

VAL-cyclovir 1g tablets (Valtrex). Disp 4 tablets. 2 tablets at onset of symptoms then 2 more 12hrs later

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14
Q

Name that condition: unilateral distribution on skin and intraorally (following a dermatome). What’s the causative agent?

A

herpes zoster…HHV3 vericella zoster

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15
Q

What are the 4 types of LONG duration (months) GENERALIZED VESICULOEROSIVE lesions?

A

1.Pemphigus Vulgaris 2.Pemphigoid 3. Erosive Lichen Planus 4.Lupus

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16
Q

What is the only example of a SHORT duration (days) generalized vesiculoerosive lesion?

A

Erythema Multiforme

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17
Q

What is the only example of a SHORT (days) or LONG (months) generalized vesiculoerosive lesion?

A

Drug-induced mucositis

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18
Q

A positive Nikolsky sign is the induction of a ______ by lateral pressure or application of air

A

BULLAE

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19
Q

Pemphigus Vulgaris is an autoimmune disease attacking epithelial __________..is this in keratinized or non-keratinized tissue?

A

desmosomes…does not discriminate between karatin/non-keratin

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20
Q

Lupus Erythematosis: what are the two kinds?

A

SLE and chronic cutaneous lupus erythematosis

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21
Q

What are the three main areas affected by SLE? What are the consequences of each area?

A

1.Heart-endocarditis 2.kidney-renal glomeruli (glomerulonephritis); 3. skin-butterfly rash on face

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22
Q

50% of ERYTHEMA MULTIFORME has no predisposing factor. The other half can be due to what 3 causes??

A

1.herpes 2.pneumonia 3.medications

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23
Q

What is the name for MAJOR erythema multiforme?

A

Steven Johnson’s syndrome

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24
Q

Besides the minor and major forms of erythema multiforme, what is the third type?

A

Toxic Epidermal Necrolysis

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25
What are the 3 KEY FEATURES of Erythema Multiforme?
1.ACUTE onset (days) of generalized oral ulcerations 2.TARGET Lesions (not always present) 3. BLACK crusty lips
26
The typical name for inflammatory bowel disease affecting anywhere from the oral cavity to the anus:
Crohn's disease
27
Where are the lesions of Crohn's disease most commonly found? What is the CARDINAL SIGN?
small intestines..cobblestoning of the mucosa
28
What are the 4 oral manifestations of Crohn's Disease?
1. Labial Swelling 2. Apthous ulcers 3.Mucosal tags 4.Granulomatous gingivitis
29
Inflammatory fibrous hyperplasia is also known as
Epilus Fissuratum
30
Which part of a denture is most commonly to blame for an epilus fissuratum?
the flange
31
If the flange of a denture mainly causes inflammatory FIBROUS hyperplasia, what does the intaglio surface of the denture cause?
inflammatory PAPILLARY hyperplasia
32
Where is the most common place for a denture leaf fibroma?
hard palate
33
a WARTY tumor is assoicated with what causative agent?
human papilloma virus
34
What type of lesion am I describing? Surfase is roughened or has multiple FINGER-LIKE projections that are often WHITE
Benign Warty Tumor of Squamous Epithelium (caused by HPV)
35
What lesion is this describing? A PEDUNCULATED attachment HPV (pedunculated base is smaller than mass)
papilloma = pedunculated
36
What lesion is this describing? a SESSILE attachment of HPV (sessile-base is same size or larger than mass)
Verruca vulgaris
37
What lesion is this describing? multiple, sessile attachment of HPV that is sexually transmitted
Condyloma (using condyles during STD transfer)
38
Condylomas are associated with which 3 HIGH RISK HPVs?
16,18,31
39
THE FIVE P's for a GUM BUMP differential (not growing in bone!)
1.Parulis 2.Pyogenic Granuloma 3.Peripheral Ossifying FIbroma 4.Peripheral Giant Cell Granuloma 5. Plain fibroma
40
Peripheral Ossifying Fibroma-blanch or no blanch?
NO, does not blanch
41
Peripheral Giant Cell Granuloma-blanch or no blanch?
Yes, blanch
42
What two colors best describe a peripheral giant cell granuloma?
red-purple
43
What lesion am I describing? Easily bleeds, blanches, and is increased frequency in pregnant women?
Pyogenic granuloma
44
What are the two 'P' lesions that are PINK?
Peripheral ossifying fibroma (both pink and red) and plain fibroma
45
What are the three 'P' lesions that are RED?
Pyogenic granuloma, peripheral ossifying fibroma (both pink and red), peripheral giant cell granuloma
46
Note: Salivary gland lesions do NOT occur in what area of the mouth?
gingiva
47
"Other bumps": what are the two of FIBROUS tissue origin?
1. irritation fibroma 2.peripheral ossifying fibroma
48
"Other bumps": What are the two of VASCULAR origin?
1.pyogenic granuloma 2. peripheral giant cell granuloma
49
"Other bumps": What are the 3 of NERUAL origin? (hint one has 2 names)
1.Neurofibroma/Schwannoma 2. Traumatic neuroma 3. Granular cell tumor
50
"Other bumps": what is the only neural bump that is painful?
Traumatic neuroma
51
"Other bumps": What is the most common site of a granular cell tumor?
Dorsum of tongue
52
"Other bumps": Which tumor of nerual origin may exhibit PSEUDOEPITHELIOMATOUS HYPERPLASIA (resembling SCC histologically)
granular cell tumor
53
"Other bumps": What are the two of muscle origin?
Leiomyoma (smooth muscle), Rhabdomyoma (skeletal muscle)
54
"Other bumps": Where will you NEVER find a Rhabdomyoma?
gingiva or palate (no skeletal muscle present)
55
"Other bumps": What is the only tumor of fat origin? What two colors best describe this?
Lipoma.. yellow or pink
56
"Other bumps": What is the only tumor of UNKNOWN origin? Where are they typically found? What gender is affected more?
Congenital Epilus...present at birth, on alveolar ridge, 90% female
57
How are all "BUMPs" treated?
Excision
58
What lesion am I talkin' bout? occurs in waldeyers ring. well circumscribed, pale-yellow in color
Lympho-epithelial cyst
59
What are the three main places an lymphoepithelial cyst can show up? (hint waldeyer's ring)
floor of mouth, lateral tongue, tonsillar pillar
60
What lesion am I talkin' bout? Frog-egg appearance on dorsum of tonuge
Lymphangioma
61
What lesions am I talkin bout? lymph-filled superficial vessels
Lymphangioma
62
Does lymphangioma blanch?
does not blanch, does not contain blood
63
What are the three descriptors/results in the blood for Leukemia?
1.Anemic 2.Leukopenic 3.Thrombocytopenic
64
Leukemia-what am I describing? reduced RBCs, fatigue and shortness of breath
anemia
65
Leukemia: what component am I describing? reduced WBCs and therefore increasing possiblity of infection
leukopenia
66
Leukemia: what component am I describing? reduced platlets leading to prolonged and easy bleeding
thrombocytopenia
67
Oral manifestations of Leukemia: ________ and pupura of the oral mucosa
petechiae
68
Oral manifestations of Leukemia: spontaneous and prolonged gingival _______
bleeding
69
Oral manifestations of Leukemia: boggy gingival ________ and ulcerations...what is causing this?
enlargement...WBCs spilling out into soft tissue
70
Oral manifestations of Leukemia: ________ due to decreased immune function
candidiasis
71
Oral manifestations of Leukemia: ______ or _____ lesions can occur anywhere due to the immunocompromise
herpes or aphthous ulcers
72
What are two lab tests to help diagnose Leukemia? What will you find?
CBC and WBC differential...elevated WBC, everything else decreased
73
Name that lesion: teeth floating in air, scooped out bone
Langerhans cell disease
74
What is the cause of Langerhans cell disease? What shows histologically?
Unknown...proliferation of Langerhans cells
75
Langerhans Cell Disease...THE SPECTRUM OF MANIFESTATION. ________ Granuloma-one or more bone lesions
Eosinophilic granuloma
76
Langerhans Cell Disease...THE SPECTRUM OF MANIFESTATION....Chronic disseminated AKA _____-_____ _________ showing bone lesions, exopthalmos, and diabetes insipidus
Hand-Schuler Christionson
77
Langerhans Cell Disease...THE SPECTRUM OF MANIFESTATION...Acute disseminated AKA _______-_____ fond in skin, bone, and internal organs
Letterer-Siwe
78
What is a multifocal malignancy of PLASMA cells?
multiple myeloma
79
What can you see in the urine or serum of multiple myeloma patients?
Bence-Jones proteins
80
What am I describing? Well-defined, punched out lesions on a readiograph
multiple myeloma