ORAL PATH REVIEW POWERPOINT 2 Flashcards

1
Q

Taumatic Ulcer: anything lasting for more than _______ should be biopsied

A

2 weeks

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2
Q

NAME THAT CONDITION: unknown cause and not infectious; found on NON-KERATINIZED tissue; 3 forms are minor, major, and herpetiform; red halo surrounding central yellow/ white area

A

Apthous Stomatitis

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3
Q

What are the three forms of Apthous Stomatitis?

A

Minor, Major, Herpetiform

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4
Q

What is the treatment for Apthous Stomatitis?

A

Corticosteroids

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5
Q

________ herpes can be found on BOTH keratinized and non-keratinized tissue

A

PRIMARY

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6
Q

Which type of herpes outbreak is associated with fever, malaze, and lymphadenopathy (but may be subclinical)?

A

Primary

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7
Q

Which type of herpes outbreak is typically asymptomatic?

A

recurrent

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8
Q

_______ herpes found on keratinized tissue only

A

RECURRENT

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9
Q

Name that type of herpes: prodrome usually proceeds

A

recurrent

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10
Q

Name that type of herpes: found in the same location

A

recurrent

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11
Q

How long do you have to tx Primary Herpes?

A

within 3 days

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12
Q

What can you treat Primary Herpes? What is the tx regimen? (for children and adults)

A

A-CYCLOVIR (A is primary) suspension rinse and swallow 5x/day. Children 15mg/kg. Adults 200mg

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13
Q

What can you treat recurrent herpes with? What is the tx regimen?

A

VAL-cyclovir 1g tablets (Valtrex). Disp 4 tablets. 2 tablets at onset of symptoms then 2 more 12hrs later

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14
Q

Name that condition: unilateral distribution on skin and intraorally (following a dermatome). What’s the causative agent?

A

herpes zoster…HHV3 vericella zoster

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15
Q

What are the 4 types of LONG duration (months) GENERALIZED VESICULOEROSIVE lesions?

A

1.Pemphigus Vulgaris 2.Pemphigoid 3. Erosive Lichen Planus 4.Lupus

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16
Q

What is the only example of a SHORT duration (days) generalized vesiculoerosive lesion?

A

Erythema Multiforme

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17
Q

What is the only example of a SHORT (days) or LONG (months) generalized vesiculoerosive lesion?

A

Drug-induced mucositis

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18
Q

A positive Nikolsky sign is the induction of a ______ by lateral pressure or application of air

A

BULLAE

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19
Q

Pemphigus Vulgaris is an autoimmune disease attacking epithelial __________..is this in keratinized or non-keratinized tissue?

A

desmosomes…does not discriminate between karatin/non-keratin

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20
Q

Lupus Erythematosis: what are the two kinds?

A

SLE and chronic cutaneous lupus erythematosis

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21
Q

What are the three main areas affected by SLE? What are the consequences of each area?

A

1.Heart-endocarditis 2.kidney-renal glomeruli (glomerulonephritis); 3. skin-butterfly rash on face

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22
Q

50% of ERYTHEMA MULTIFORME has no predisposing factor. The other half can be due to what 3 causes??

A

1.herpes 2.pneumonia 3.medications

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23
Q

What is the name for MAJOR erythema multiforme?

A

Steven Johnson’s syndrome

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24
Q

Besides the minor and major forms of erythema multiforme, what is the third type?

A

Toxic Epidermal Necrolysis

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25
Q

What are the 3 KEY FEATURES of Erythema Multiforme?

A

1.ACUTE onset (days) of generalized oral ulcerations 2.TARGET Lesions (not always present) 3. BLACK crusty lips

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26
Q

The typical name for inflammatory bowel disease affecting anywhere from the oral cavity to the anus:

A

Crohn’s disease

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27
Q

Where are the lesions of Crohn’s disease most commonly found? What is the CARDINAL SIGN?

A

small intestines..cobblestoning of the mucosa

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28
Q

What are the 4 oral manifestations of Crohn’s Disease?

A
  1. Labial Swelling 2. Apthous ulcers 3.Mucosal tags 4.Granulomatous gingivitis
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29
Q

Inflammatory fibrous hyperplasia is also known as

A

Epilus Fissuratum

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30
Q

Which part of a denture is most commonly to blame for an epilus fissuratum?

A

the flange

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31
Q

If the flange of a denture mainly causes inflammatory FIBROUS hyperplasia, what does the intaglio surface of the denture cause?

A

inflammatory PAPILLARY hyperplasia

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32
Q

Where is the most common place for a denture leaf fibroma?

A

hard palate

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33
Q

a WARTY tumor is assoicated with what causative agent?

A

human papilloma virus

34
Q

What type of lesion am I describing? Surfase is roughened or has multiple FINGER-LIKE projections that are often WHITE

A

Benign Warty Tumor of Squamous Epithelium (caused by HPV)

35
Q

What lesion is this describing? A PEDUNCULATED attachment HPV (pedunculated base is smaller than mass)

A

papilloma = pedunculated

36
Q

What lesion is this describing? a SESSILE attachment of HPV (sessile-base is same size or larger than mass)

A

Verruca vulgaris

37
Q

What lesion is this describing? multiple, sessile attachment of HPV that is sexually transmitted

A

Condyloma (using condyles during STD transfer)

38
Q

Condylomas are associated with which 3 HIGH RISK HPVs?

A

16,18,31

39
Q

THE FIVE P’s for a GUM BUMP differential (not growing in bone!)

A

1.Parulis 2.Pyogenic Granuloma 3.Peripheral Ossifying FIbroma 4.Peripheral Giant Cell Granuloma 5. Plain fibroma

40
Q

Peripheral Ossifying Fibroma-blanch or no blanch?

A

NO, does not blanch

41
Q

Peripheral Giant Cell Granuloma-blanch or no blanch?

A

Yes, blanch

42
Q

What two colors best describe a peripheral giant cell granuloma?

A

red-purple

43
Q

What lesion am I describing? Easily bleeds, blanches, and is increased frequency in pregnant women?

A

Pyogenic granuloma

44
Q

What are the two ‘P’ lesions that are PINK?

A

Peripheral ossifying fibroma (both pink and red) and plain fibroma

45
Q

What are the three ‘P’ lesions that are RED?

A

Pyogenic granuloma, peripheral ossifying fibroma (both pink and red), peripheral giant cell granuloma

46
Q

Note: Salivary gland lesions do NOT occur in what area of the mouth?

A

gingiva

47
Q

“Other bumps”: what are the two of FIBROUS tissue origin?

A
  1. irritation fibroma 2.peripheral ossifying fibroma
48
Q

“Other bumps”: What are the two of VASCULAR origin?

A

1.pyogenic granuloma 2. peripheral giant cell granuloma

49
Q

“Other bumps”: What are the 3 of NERUAL origin? (hint one has 2 names)

A

1.Neurofibroma/Schwannoma 2. Traumatic neuroma 3. Granular cell tumor

50
Q

“Other bumps”: what is the only neural bump that is painful?

A

Traumatic neuroma

51
Q

“Other bumps”: What is the most common site of a granular cell tumor?

A

Dorsum of tongue

52
Q

“Other bumps”: Which tumor of nerual origin may exhibit PSEUDOEPITHELIOMATOUS HYPERPLASIA (resembling SCC histologically)

A

granular cell tumor

53
Q

“Other bumps”: What are the two of muscle origin?

A

Leiomyoma (smooth muscle), Rhabdomyoma (skeletal muscle)

54
Q

“Other bumps”: Where will you NEVER find a Rhabdomyoma?

A

gingiva or palate (no skeletal muscle present)

55
Q

“Other bumps”: What is the only tumor of fat origin? What two colors best describe this?

A

Lipoma.. yellow or pink

56
Q

“Other bumps”: What is the only tumor of UNKNOWN origin? Where are they typically found? What gender is affected more?

A

Congenital Epilus…present at birth, on alveolar ridge, 90% female

57
Q

How are all “BUMPs” treated?

A

Excision

58
Q

What lesion am I talkin’ bout? occurs in waldeyers ring. well circumscribed, pale-yellow in color

A

Lympho-epithelial cyst

59
Q

What are the three main places an lymphoepithelial cyst can show up? (hint waldeyer’s ring)

A

floor of mouth, lateral tongue, tonsillar pillar

60
Q

What lesion am I talkin’ bout? Frog-egg appearance on dorsum of tonuge

A

Lymphangioma

61
Q

What lesions am I talkin bout? lymph-filled superficial vessels

A

Lymphangioma

62
Q

Does lymphangioma blanch?

A

does not blanch, does not contain blood

63
Q

What are the three descriptors/results in the blood for Leukemia?

A

1.Anemic 2.Leukopenic 3.Thrombocytopenic

64
Q

Leukemia-what am I describing? reduced RBCs, fatigue and shortness of breath

A

anemia

65
Q

Leukemia: what component am I describing? reduced WBCs and therefore increasing possiblity of infection

A

leukopenia

66
Q

Leukemia: what component am I describing? reduced platlets leading to prolonged and easy bleeding

A

thrombocytopenia

67
Q

Oral manifestations of Leukemia: ________ and pupura of the oral mucosa

A

petechiae

68
Q

Oral manifestations of Leukemia: spontaneous and prolonged gingival _______

A

bleeding

69
Q

Oral manifestations of Leukemia: boggy gingival ________ and ulcerations…what is causing this?

A

enlargement…WBCs spilling out into soft tissue

70
Q

Oral manifestations of Leukemia: ________ due to decreased immune function

A

candidiasis

71
Q

Oral manifestations of Leukemia: ______ or _____ lesions can occur anywhere due to the immunocompromise

A

herpes or aphthous ulcers

72
Q

What are two lab tests to help diagnose Leukemia? What will you find?

A

CBC and WBC differential…elevated WBC, everything else decreased

73
Q

Name that lesion: teeth floating in air, scooped out bone

A

Langerhans cell disease

74
Q

What is the cause of Langerhans cell disease? What shows histologically?

A

Unknown…proliferation of Langerhans cells

75
Q

Langerhans Cell Disease…THE SPECTRUM OF MANIFESTATION. ________ Granuloma-one or more bone lesions

A

Eosinophilic granuloma

76
Q

Langerhans Cell Disease…THE SPECTRUM OF MANIFESTATION….Chronic disseminated AKA _____-_____ _________ showing bone lesions, exopthalmos, and diabetes insipidus

A

Hand-Schuler Christionson

77
Q

Langerhans Cell Disease…THE SPECTRUM OF MANIFESTATION…Acute disseminated AKA _______-_____ fond in skin, bone, and internal organs

A

Letterer-Siwe

78
Q

What is a multifocal malignancy of PLASMA cells?

A

multiple myeloma

79
Q

What can you see in the urine or serum of multiple myeloma patients?

A

Bence-Jones proteins

80
Q

What am I describing? Well-defined, punched out lesions on a readiograph

A

multiple myeloma