Pharm Exam 4 Flashcards

1
Q
  1. Uti Treatment x5
  2. Super infection
  3. Gram Negative Drugs x1
  4. Gram Positive Drugs x2
A
  1. Bactrim, Amoxicillin, Fluroquinolones, Macrodantoin, Pyridium (BAFMyPee)
  2. Broad Spectrum, infection on top of earlier infection, THRUSH, Vag YEAST
  3. Aminoglycoside
  4. Antitubercular
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2
Q
  1. Bacteriostatic
  2. Bacteriocidal
  3. Drugs that contain -static and -cidal x3
  4. ototoxcity drugs x3
A
  1. inhibits growth, lower dose
  2. kills, higher dose
  3. penicillin, macrolides, lincosamides
  4. Vanomycin, Amphoteracin, Gentamycin
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3
Q
  1. -vir
  2. -mine
  3. -zine
  4. -mycin
  5. exception to mycin
A
  1. antivirals
  2. 1st generation antihistamine
  3. 2nd generation antihistamine
  4. lincosamide
  5. aminoglycoside, know gentamycin
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4
Q
  1. Liver Toxicity
  2. Renal Toxicity
  3. Creatnine BUN
A
  1. Ketoconazole, RTI, Protease, INH, Tetracycline, Macrodantin
  2. Amphoteracin HIGH, Gentamycin, Acyclovir, Tetra, Vanomycin
  3. Peptides, acycloir, gentamycin
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5
Q
  1. GI upset
  2. Peripharl Neruopathy
  3. This is not an antibiotic
  4. Narrow Spectrum drug
A
  1. Fluroquinolones Ampicillin, , MAcrodantoin, Erythromycin famous gi upset!
  2. INH
  3. Pyridium
  4. Aminoglycoside
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6
Q
  1. Take with food
  2. Empty stomache
  3. Food or no food
A
  1. erythromycin, flagyl, macrodantoin (efoom)
  2. penicillin, INH, Tetra (pit, hole)
  3. ampicillin- watch CITRUS
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7
Q
  1. First generation antihistamine
  2. 2nd generation antihistamine
  3. SE of Oral antihistamine
  4. Most effective antiasthma drug
A
  1. Sedating
  2. Non-sedating
  3. anticholinergic- dry mouth, constipation, urinary retention
  4. glucocorticoids
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8
Q
  1. Long term, prophylaxis Asthma prevention x3
  2. Side effects of glucocorticoid inhaler
  3. Why do you rinse your mouth with glucocorticoid inhaler?
  4. Used with glucocorticoid inhaler?
  5. Cromolyn
A
  1. Glucocorticoid inhaler, Long Acting inhaled Beta 2 agonist, Comolyn
  2. throat, dry mouth, cough
  3. oral fungal infections
  4. Long acting Beta 2 Agonist
  5. Mast cell wall stabilixer, prevents mediators
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9
Q
  1. Acute Asthma treatment
  2. SE of oral glucocorticoids
  3. How can you take Selective Beta 2 Receptor?
  4. Categories for Beta 2 Agonist/Bronchodilator Agents
A
  1. Oral glucocorticoids, Selective Beta 2 Receptor, Short Acting inhaled Beta 2
  2. peptic ulcer, T.E., must taper
  3. nebulizer, inhaler, systemic effects w/ oral
  4. methyxanthines, anticholinergics
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10
Q
  1. What part does asthma effect?
  2. Types of antiinfammatory agents
  3. What does cromolyn do?
  4. What is a leukotriene
  5. Singulair
A
  1. Lower respiratory tract
  2. Glucocorticoids, cromolyn, leukotriene modifiers, IgE antagonist
  3. Stabilize Mast Cell Wall
  4. chemical mediator for inflammatory response
  5. Leukotriene antagonist, bronchodilation
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11
Q
  1. Asthma.Methylxanthin derivative agents
  2. Methylxanthin agents cause…
  3. Theophylline OFF market
  4. Theophylline action
  5. How do you give it?
A
  1. Aminophylline, Theophyline, Caffeine
  2. bronchodilation, CNS excitation, Vasodilation, Cardiac stimulus, diuresis
  3. Too many SE, narrow window,
  4. relaxes smooth muscle of bronchi
  5. IV or oral
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12
Q
  1. Aminophyline
  2. Anticholinergic for Asthma (COPD off Label)
  3. Action
  4. SE of Ephedrine
  5. SE of Pseudoephedrine
A
  1. Salt Theophylline, give slow–>hypotension/death. incompatible
  2. Atrovent(inhaled), Tiotropium
  3. Bronchodilator
  4. HTN, Dysrrythmias, MI, Stroke, Seizure, hyperglycemia, OFF MARKET
  5. Cardiovasscular collapse, HTN, Seizure
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13
Q
  1. Antitussive, Upper Respiratory Tract, cough
  2. Dextromethorphan
  3. Diphenydramine
  4. Non drowsy, antihistamine for hay fever
A
  1. Relief of non productive cough, medulla, drowsiness
  2. Non-narcotic, OTC, cold remedy
  3. also a antihistamine, help to sleep, allergy, cold, cough
  4. Fexofenadine/Allegra
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14
Q

Allergic Rhinitis, MAST CELL

  1. Histamines
  2. Leukotrines
  3. Prostaglandins
A
  1. vasodilate, itching, mucus, inc cap perm, bronchoconstrict
  2. asthma, bronchoconstrict, mucus, airway, edema
  3. vasodilate, fever, PAIN, inc cap permeability
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15
Q
  1. Glucocorticoids and allergies
  2. First line thearpy for allergic rhinitis
  3. What else cane you use to treat allergy?
  4. Antihistamine prophylaxxis allergy treatment
A
  1. dec inflam, inhibit prostaglandin relese, INTRANASAL MOST effective
  2. intransal glucs, oran/intranasal antihis
  3. sympathomimetics
  4. Histamine 1, common, sneeze, rhinorrhea, itchy nose. DOESN NOT REDUCE NASAL CONGEST
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16
Q
  1. Decongestants stimulate which recptor?
  2. Action
  3. Phenylphine, Oxymetazoline, Sudafed Usage, Sympathomimetics
  4. Respiratory and Obstructive Complications
A
  1. Alpha 1 Receptor
  2. HTN, Constrict NOSE
  3. use for 5 days only, rebound congestions
  4. beta 2 adrenergic agonist
17
Q
  1. How C/S test can decrease resistance
  2. misues of antibiotics what percent?
  3. Vanomycin
  4. Side effects of Vanomycin
  5. Prevention for antibiotic use
A
  1. Actual microbe specific to antibiotic
  2. 50% use in hospital that don’t need them
  3. Effective against MRSA (avoid use), GLYCOPEPTIDE
  4. redman syndrome, slow iv or pump
  5. vaccines, limit catheters, c/s before, handwashing
18
Q
  1. Gen Broad spectrum antibiotics
  2. Penicillin Action
  3. Most common type of penicillin
  4. Allergy alternative to Penicillin
  5. Macrolide
A
  1. Thromycin
  2. Beta lactam, interfere with cell wall, LYSE
  3. Amoxicillin, low resp infection, skin infection,
  4. Erythromyciin (Macrolide)
  5. supress protein synthesis, bacteriostatic
19
Q
  1. Antibacterial Categories
  2. How do you treat allergic reactions?
  3. Gram+
  4. Gram -
  5. Mycostatin
A
  1. Penicillins, cephlosporins, macrolides, lincosamides, sulfonamides, glycopeptides, aminoglycoside, tetra, fluroquinolones, antTB, antifungal
  2. antihistamins, bronchoDILATORS, ephinephrine
  3. thick wall, purple (cocci)
  4. thin wall, violet, neisseria
  5. antifungal, candidiasis, leakage membrane
20
Q
  1. Lincosamides,
  2. Resemblence to Penicillin
  3. Penicillin resistance
  4. Penicillin patient education
  5. Cephalosporin
A
  1. inhibit protein synthesis, SE colitis, rash, antiacne
  2. cephalosporin
  3. Staph, MRSA, Methicillin (NOMARKET)
  4. reduce contraceptive, take entirety, stomatitis, vaginits, c/s before
  5. most common, less side effects, broad spectrum
21
Q
  1. Tetracycline uses
  2. Adverse effects
  3. Why vitamin b6 and inh
  4. Flagyl action
  5. Alcoholic effects of flagyl
A
  1. Chlamydia, anthrax, cholera, lyme, ulcer, acne, pneumonia, rm spotted fever
  2. photo, discolr teeth, NO <8yrs, dec effective of BC pills
  3. decrease peripheral neuropathy
  4. Impairs DNA function of bacteria, antibiotica, antiprotozoal
  5. causes disulifiram, for alcoholics
22
Q
  1. Flagyl Use
  2. Colorectal surgery
  3. Adverse effects
  4. Gentamycin what will you watch for?
  5. Administer Gentamycin how
A
  1. GI, GI, CNS, C.DIFF, antiulcer, antiinefect, antiprotozoal
  2. flagyl, prophylaxis
  3. dark urine,
  4. narrow window, urin output, balance, hearing
  5. IM IV
23
Q
  1. Potent antibiotic
  2. Adverse effects
  3. Decrease risk of crystalluria
  4. What is fluroquinolones good for?
A
  1. Fluroquinolones, not 1st line treatment
  2. photo, gi, crystalluria
  3. increse fluid intake
  4. tissue penetration, respiratory tract infection, inhibit DNA synthesis.
24
Q
  1. Antiseptic, antiinfective
  2. Baceter…
  3. Adverse Effect
  4. Pyridium and urine
A
  1. **Macrodantin **UTI’s
  2. cidal, static
  3. peripheral neruopathy,dizzy, drowsy RUSTY URINE
  4. analgesic w/ antibiotic discolors urine. NOT ANTIMICROBIAL, take when symptoms are gone
25
Q
  1. Sulfanomides
  2. What do sulfanomides treat
  3. Silvadene
  4. Action of sulf
A
  1. Bactrim, Septra, bronchitis too
  2. UTI-E.coli, otitis media, newborn eye prophylaxis
  3. Topical, for burns
  4. interefers with folic acid synthesis, -static
26
Q
  1. Amphotericin B category
  2. administration
  3. Action of amph B
  4. Drug of choice for ringworm, alternative to ampho
A
  1. polyene, antifungal, RENAL, severe (mening in HIV patients)
  2. IV only
  3. binds to membrane allow leakage
  4. ketoconazole
27
Q
  1. This is an antiretroviral agent used to treat HIV
  2. HAART
  3. Cocktail for HAART
  4. How long for use
  5. Adverse Effects
A
  1. AZT
  2. Highly Active Antiretrioviral Therapy
  3. 2 Rti’s with Protease inhibitor
  4. lifetime
  5. drug interaction, anemia neutropenia, anorexia,liver, lactic acidosis
28
Q

HAART

  1. Action
  2. Safety
  3. Assess
A
  1. undetectable viral lode, improves CD4 count
  2. does not prevent trasnmission, need refular follow up exams
  3. hypersenstivity
29
Q

Neurominidase inhibitors

  1. What does it treat
  2. when should you take it
  3. How does it treat?
A
  1. release of virus from infected cells
  2. within 48 hours of flu symptoms
  3. Inhibits the enzyme, may alter virus Particle
30
Q
  1. Antiviral, Antiherpes
  2. Route
  3. action
  4. Treats
  5. Adverse effects
A
  1. acyclovir,
  2. Topical, oral IV (oral prevents recurrence)
  3. varicella zoster, EBV, herpes
  4. gingival hyperplasia, encourage fluids, renal BUN
31
Q
  1. AntiTB bacteria
  2. How is it transmitted
  3. Cell wall
  4. How long for treatment
  5. Approach
A
  1. Acid Fast Bacillus (rods)
  2. droplet
  3. Thick, resitat to penetration by antiinfectives
  4. 6-24 months
  5. Use combo drugs
32
Q
  1. What is Isoniazide
  2. Action
  3. Route
  4. Labs
  5. SE
A
  1. prophylaxis antiTB
  2. inhibts mycobacterial cell wall synthesis and intereferes with metabolism
  3. First oral drug affective against TB
  4. Liver enzymes, Sputum samples morning
  5. Peripheral neuropathy b6
33
Q

1. Expectorants drugs

  1. Define Expectorant
  2. Has both Adrenergic and Corticosteroid
A
  1. Robitussin,
  2. Liquefy secretions, increases respiratory tract fluid
  3. Symbicort, Advair