Maternal/Newborna Exam 3 Flashcards
What is Methotrexate used for
- carcinomas
- it interferes with folic acid metabolism
- Inhibits DNA synthesis.
used for ectopic pregnancy
Hyperemesis Gravidarum is a different type of morning sickness
sick during pregnancy, could cause electrolyte imbalance
What causes hyperemesis Gravidarum
Vitamin B6 deficiency (give 3x a day) NOT hCG levels
Phenergan
- increases narcotics
- slows down metabolism of the narcotic
- anti-emetic, good for if woman is dizzy
Reglan
Antiemetic during chemotherpy
Zofran
anti-emetic for chemotherapy
Preeclampsia
hypertension after 20 weeks gestation w/ proteinuria (>1+) (140/90+)
Eclampsia
when preeclampsi turns into a seizure
chronic htn
before 20 weeks, trace proteinura. Persists > 42 days following childrbirth
What is too much protein
1+ or 2+ is greater than “trace”
What type of vessels do preeclampsia women have
flaccid
Preeclampsia do they have vasoconstriction or vasodilated
vasoconstricted, calcified. (dec leveled of vasdilating prostglandins)
What hormone do preeclampsia have a decreased resistance to?
angiotensin II (make cells more flaccid)
When assessing woman for preeclampsia what location is the liver
RUQ
Signs/Sx of Preeclampsia
- Headache/Blurred Vision
- Facial Edema
- pulmonary edema, no crackles
- BP- increased
- Liver distended/painful
- AST/ALT elevated
- lacking albumin, 3rd spacing
- reflexes, hyperreflexia
- clonus,
- oliguria
normal response during pregnancy H/H
decreased due to increased plasma
preeclampsia will have what type of h/h
falsely high
Mild Preeclampsia
Hypertension and proteinuria
Severe preeclampsia
>160 mm organ failure
Treatment for preeclamps
- Magnesium sulfate, NOT anti-hypertensive
Magenesium Sulfate
- acts like a calcium channel blocker, but not antihypertensive
- prevents seizure
- check q 15min
Why do we give corticosteroids for preeclampsia
for baby
Hydralazine
used to lower blood pressure
HELLP syndrome
- hemolysis
- elevated liver enzymes
- low platelet count (thrombocytopenia)
What is thrombocytpenia
< 150,000
Clinical Manifestation of HELLP
- RUQ pain
- jaundice
- liver rupture
Only cure for preeclampsia
delivery of the placenta
How should a preeclamptic woman deliver?
vaginally, scary bc of water intoxification
Rhogam within how many hours after delivery
72 hours
What does coombs test for?
antibodies
Pathological Jaundice
- ABO incompatibility
- O blood type, type A or B fetus
- can’t give rhogam
- hyperbilirubemia, anemia
When do we test GBS
36 weeks
What should we give for GPS positive
penicillin G q4 hours. birthing process puts baby at risk.
Magnesium sulfate classification
CNS depressant
What is the dose for magnesium sulfate
4-6 grams, A LOT.
What is the antidote for magensium sulfate
calcium gluconate
Side Effects of Magnesium Sulfate (Maternal)
- depressed respiration
- depressed DTRs
- hypotension
- extreme muscle weakness
- flushing
- decreased u. output
- pulmonary edema
- > 9 mg/dl serum mag
DTR clonus for magnesium sulfate
hyporreflexia
What is the major vital sign we need for magnesium sulfate?
pulse oximeter
How is magnesium sulfate excreted?
through the urine
What type of drug is Mag Sulfate
- CNS depressant
- tocolytic
- neuro protection for mom/fetus
- treat/prevent eclampsia
Who would be an indication for induction?
someon at 39 weeks and not progressing
What should you do in the even of fetal distress?
prep client for emergency c-section
Risks for preterm labor
- infection
- gestational diabetes
- uterine fibroids
- medications
What is a premature rupture of membranes>
ruptured earlier than the end of 37th week. Greater risk if before 34th week.
Cold stress causes oxygen consumption and energy to be diverted from maintaining normal brain cell function and cardiac functinon, what is the result?
- metabolic and physiologic
Characteristics of placenta previa
- painless
- brigh red vaginal bleeding
- uterus is soft/relaxed/nontender
What is the fibronectin test?
positive means onset of labor in 1 to 3 weeks
What is a normal contraction frequency?
no more frequen than 1-1/2 min
What is the first line of defense for an obstetric emergency
cardiopulmonary resuscitation
What part do you suction first mouth or nose?
mouth
Circumcision Care
- Vitamin K prior
- feeding witheld 2-4 hrs
- bulb syringe ready
- Petroleum jelly over the site to prevent diaper from sticking
- diaper attached loosely
What actions should you take if the membranes have ruptured
- assess the FHR b/c of risk of collapsed umbiical cord
- asses the color of the amniotic fluid b/c meconium stained fluid can indicate fetal stress.
Describe Colostrum
- high in protein, low in carbs/fat
- rich in IgA- protects GI
- helps normal flora
- speeds passage of meconium (laxative effect)
What can happen with oligohydramnios
- ruptured membranes
- placental insufficiency
- SGA
- limited oxygen
What is a precipitous labor/birth
labor and delivery after an unusually short amount of time
What is the fern test
determines the presence of amniotic fluid leakage. Produces a fernlike pattern b/c of salts
What can substance abuse do to the fetus
risk for fetal growth restriction, abruptio placentae, and fetal bradycardia
Nursing interventions for tachysystole?
- reduce oxytocin
- increase infusion
- lateral position
- give oxygen
- notify physican
What could be indications for bradycardia?
- fetal head compression
- umbilical cord compression
What candidate would not be good for a VBAC
if she had a vertical incision
Why does a newbor recieve erythromycin?
Opthalmia Neotorium
Proper communication for a woman experiencing grief and loss
be specific with care, don’t ask why, or “is everything okay”
Post date concerns > 42 weeks
- LGA
- oligohydramnios- umbilical cord compression
- green meconium staining
- less reserve to tolerate contractions
- Respiratory distress
- exhaust stores of glycogen
- Injury
- hemorrhage
How long is too long for a newborn to have apnea?
10-15 seconds
What is a normal contraction duration
no longer than 90-120 sec
Name 4 reasosn why a newborn receives vitamin K
- hemorrhagic disease
- stroke
- clotting
- gut is still sterile
What is an example of a conductive heat loss?
cold hands, stethoscope, wipes, cool surface
Causes for cord prolapse
- premature rupture of membranes
- high station
- blugin bag of water
- unengageed presenting part
Most important assessment when baby is born?
breath
cardiopulmonary changes need to occur
Whats a good measure of fetal heart rate in relation to mother?
its about twice the mothers
5 type of obstetric emergencies?
- hypovolemia
- PPH
- Amniotic fluid embolism
- prolase cord
- shoulder dystocia
What side of the heart can an amniotic embolism effect?
left side
Risks for preterm infants
- inadequate brown fat stores
- 80 % risk for jaundice
- immature conjucation abilities
- diminished reflexes (sucking)
- flaccid or rigid extremities
What does labor dystocia mean?
abnormally low progress of labor, inadequate pelvis shape, multifetal, PROM, bladder distention.
could be caused by infection
What should you do if you see a positive nitrizine/ferning test?
check temp an FHR (amniotic fluid is present)
What is a nitrazine test?
used to detect the presence of amniotic fluid in the vaginal secretions
Amniotic fluid has a pH of 7.0 - 7.5
When should pitocin be discontinued?
- frequency is less than 2 minutes
- duration longer than 90 sec
- fetal distress
What can cause uterine rupture
- pitocine due to intense contractions
- precipitate labor
- if bleeding is excessive and uterus is still firm
- tachysystole
- VBAC
- chest pain in shoulder
Correlations to precipitous birth
- abruptio placentae, fetal meconium, pph, low apgar score, cocaine, nerve damage, ROM, risk for sepsis, chorioamnionitis
What could be indications for tachycardia
- maternal severe anemia
- maternal hyperthydroidism
- drugs (bronchodilators, decongestants)
What drugs are used for preterm labor
tocolytics, corticosteroids.
What is an example of evaporative heat loss?
if the baby is wet or not well wrapped
When is betamethasone contraindicated?
- chorioamnionitis
- diabetes
- pulmonary edema
- sodium and fluid retention
What can happen if fetal fibronectin appears too early
labor may begin early (fFN test)
could be caused by infection
Why is Betamethazone used in pre term labor?
acceleration of fetal lung maturity, can reduce intraventricular hemorrhage
When are vaginal exams contraindicated?
if the client is supsected of having a placenta previa
What can increase risk for RDS?
- fetal hyperinsulinemia retards cortisol production
- RBC breakdown
- Fewer albumin binding sites
What do you need to asses after an amniotomy
temperature every 2 hours
Criteria for an amniotomy
- presenting part should be cephalic
- reassuring fetal heart rate
- commitment to delivery
What is the intervention of a baby is having respiratory distress syndrome?
prep surfactant replacement therapy (endotracheal tube)
When should you hold trebutiline?
if woman is tachycardic
What are risk associated with amniotomy
- prolapsed cord
- infection
- apruptio placentae
manifestations of shoulder dystocia
- turtle head
- failure to complete external rotation
- cord gets compressed
- clavical crepitus, deformity or bruising
- nerve injury to brachial plexus
Characteristics of abruptio placentae
- dark red blood
- uterine pain/tenderness
- uterine rigidity
How much amniotic fluid does the mother have by the end of pregnancy?
800-1200 mL
Describe Lactogenesis III
- mature milk.
- 20 kcal/oz
- antibacterial components
Babies at risk for hyperbilirubemia?
- LGA/SGA
- RBC’s not getting excreted
- ABO incombatibility
- bruising/hematoma
What could be causes of premature rupture of membranes
- infections
- neisseria gonorrhea
- chorioamnioitis associated with GBS
- maternal stress
- recent vaginal intercourse
Name 5 symptoms of respiratory distress
- tachypea
- nasal flaring
- grunting
- retractins
- decreased breath sounds
What is acreda/percreda
placenta attaches to an organ, risk for PPH
Complications with oxytocin administration
- abpruptio placentaie
- impaired uterine blood flow
- uterine rupture
- FHR variability
- late decelerations.
What is shoulder dystocia
shoulder becomes lodged under the mother’s symphysis pubis during birth
Medication used to induce labor
- pitocin
- prostaglandins
- caution if woman has asthma, glaucoma
- seaweed (laminaria tents)
- transcervical catheter
Manifestation of abruptio placentae?
- ab/low back pain
- high uterine resting tone
- vaginal bleeding
- non reassuring FHR
- concealed hemorrhage
What are the nursing interventions for shoulder dystocia?
- McRobert’s maneuver
- Suprapubic pressure, kneed
- NO fundal pressure
- episiotomy
Causes of bleeding postpartum
- retained placenta
- lacerations
- hemorrhage
What are your nursing interventions for a precitous labor x4
- tocolytics
- oxgenation
- sidelying to enhance placenta blood flow
- non additive iv fluids
Causes of bleeding intrapartum
- uterine rupture
- placenta previa
- abruptio
Management of premature rupture of membrane
- labor induction
- cesarean brth
- accurate gestational age evaluation
- fetal lung maturity
What are Kubler Ross’s 5 stages of Grief?
- Denial
- Anger
- Bargaining
- Depression
- Acceptance
Induction Risks
- Tachysystole
- water intoxication
- pulmonary edema
- CHF
- Variable/Late decelerations
Interventions for RDS?
- ABG’s
- schedule eye exam for retinal damage
- suction every 2 hrs
- position on side or back
- provide nutrition
What is an example of radiative heat loss?
if they ar near cold objects and outside walls
Interventions for variable decelerations?
- change position of the mother
- administer oxygen
- discontinue pitocin
- assess vital signs
- notify HCP
- Assist amnioinfusion (warm saline
Particles that CAN pass through the placenta?
nutrients, drugs, alcohol, anitbodies, and viruses
What is the critical fetal assessment prior to any procedure?
FHR
Causes of bleeding antepartum
- previa
- abruption
- uterine rupture
- miscarriage
What is the antidoe for induction?
Trebutiline (tocolytic).
What does marked variability mean?
fetal heart rate fluctuations are greater than 25 beats/minute
What should interventions for late decelerations include?
improving placental blood flow and fetal oxygenation
What is example of convection heat loss?
near a window or draft
What is placenta previa
- placenta moves and may be covering the cervix
- may mean you will need to a C-section or induction of labor
- umbilical cord can prolapse
What is the nursing intervention for cord prolapse
- hips higher than head to shift fetus
- tendelendburg
- tocolytics
- vaginal elevation
Is jaundice the first day of life pathologic?
yes
What is a uterine rupture
a tear in the uterine wall because the uterus cannot withstand the pressure against it
What does abruptio placentae mean?
- Placenta separation before the fetus is born
- can occur with hematoma
- hypovolemic shock, clotting abnormalities
- greater risk if greater amount of amniotic fluid
If fetal bradycardia or tachycardia occur, what is your action?
- change the position of mother
- administer oxygen
- assess the mother’s vital signs
- notify the healtcare provider
Nursing interventions for post date
- induction of labor
- accurate gestational age assessment
- biophysical profile

- Transverse Lie shoulder presentation
A positive Triple/Quad Screen is what?
- Estriole low
- hCG is high
further testing necessary
Women are hypercoagulable during pregnancy, why?
protective for inevitable blood loss
What does Estrogen do? x6
- stimulates contractions
- increased elasticity of ligaments
- melanin
- decrease GI motility
- Alter’s F & E’s
- Breast Development
HEAD to TOE assesssment postpartum
- Breasts
- Uterus
- Bowel
- Bladder
- Lochia (pad an hr too much)
- Episiotomy (laceration)
- Homans/hemorrhoids/hematoma
- Emotions
What happens to peripheral vascular resistance during pregnancy?
It decreases
What are danger signs of preeclampsia? x4
- severe headache
- abdominal pain
- visual disturbance
- swelling
Interventions for Late Decelerations x6
- IV bolus of LR
- Discontinue oxytocin
- tocolytic drug
- oxygen 10L/min
- reposition
- Amnioinfusion
This is failure to decend due to placenta retention
sub involution
Should not be used if patient has asthma
hemobate
Etiology for early decelerations
fetal head compression
5 P’s of Labor
- Passage- type of pelvis
- Passenger- size of fetus, presentation
- Powers- contraction/relax uterus, voluntary efforts
- Psyche- maternal emotional status
- partners-relationship of passenger/passage
Why is there a UTI risk during pregnancy?
dilation of renal pevlis and ureters due to progesterone
What causes pseudo anemia
more plasma than rbc’s, but both increase
What is a full term pregnancy?
37-42 weeks
This is a block of sympathetic fibers, contraindicated for a women with hypovolemia?
spinal block
Meds used for bleeding
- oxytocin
- cytocec
- hemobate
- methergen
Meds used to induce labor x5
- prostaglandins (rippening)
- stripping cervix
- rupturing membranes
- catheter w/ balloon
- pitocin (oxytocin)

Longitudinal Lie Vertex Presentation
What does progesterone do?
- gallbladder prolonged emptying
- prevents bile salts from being released
- softening of joints and ligaments
Assessment for Episiotomy
- Redness
- Edema
- Ecchymosis (bruising)
- Discharge
- Approximation
Disadvantages of epidural block
hypotension
Why does blood volume increase during pregnancy?
to reserve blood loss at birth
What does a non stress test show?
- 2 fetal heart accelerations within 20 minutes
- Intact CNS
Etiology for variable deceleration
cord compression
Where is false labor felt
in the abdomen or groin
Types of Lochia
Rubra, Serosa, Alba
What position allows greater perfusion to the fetus?
Wedged to the left
What does hCG do?
maintains corpus luteum until placenta is functioning (21weeks)
Para measures…
how many were living greater than 20 weeks
Pre term
20-36.6 weeks
Biophysical Profile Assess 5 Parameters
- NST
- Fetal breathing
- fetal movements
- fetal tone
- amniotic fluid volume
What does relaxin do? x5
- opening/softening of the cervix
- prevents premature contractions
- regulates CV and Renal system
- relax vessels
- excreted by placenta
Why do you give IV fluids when administering epidural?
to keep BP stabilized
What are the 7 cardinal movement of labor
- Descent
- Engagement
- Flexion
- Internal Rotation
- Extension
- Restitution
- External Rotation
- Expulsion
Signs of malpresentation?
- you can feel bony prominence of the head pushing on sacral nerves
- back pain
What are abnormal concentrations of Alphafetoproein associated with
fetal anomalies
Advantages of using epidural block?
blocks pain and patient is fully awake
Why do hematocrit and hemoglobin levels drop during 1st and 2nd trimester?
because of blood volume expansion
How do you wake a baby up if sleeping?
Vibroacoustic Monitor
What does amniotic fluid tell you?
good organ development, placental function
What happens to heart rate during pregnancy
it increase 15-20 bpm
How many arteries/veins does a fetus have
- 2 arteries (deox to placenta)
- 1 vein (oxgenated away)
Should not be used if patient has preeclampsia
methergine
Causes for late decelerations x4
- uteroplacental insufficiency
- impaired xchange of waste products
- hypo/hypertension
- excessive uterine stimuli
What is the name of the pelvis type that is most favorable for successful labor and birth
gynecoid
Maternal insulin needs during the first trimester?
decrease
Maternal insulin needs during the 2nd and 3rd trimester?
increases, placental hormones cause insuline-resistant state
This is a condition in which the clotting cascade is activated, resulting in the formation of clots in the microcirculation
Disseminated Intravascular Coagulation (DIC)
What does the rapid and extensive formation of clots that occur in DIC do to platelets
depletes platelets and clotting factors.
results in bleeding and vascular occlusion of organs from thromboembolus formation
What should all clients be assessed for during during the postpartum period
depression
What is a normal temp during the first 24 hours postpartum
100.4 F due to dehydration, greater indicates infection
A patient is taking magnesium sulfate and has respirations of 10, what should you do?
call the HCP
How should you administer magnesium sulfate
IV infusion via an infusion monitoring device
- Uti Treatment
- Super infection
- Gram Negative Drugs
- Gram Positive Drugs
- Bactrim, Amoxicillin, Fluroquinolones, Macrodantoin, Pyridium
- Broad Spectrum, infection on top of earlier infection, THRUSH, Vag YEAST
- Aminoglycoside
- Antitubercular, penicillin
- Bacteriostatic
- Bacteriocidal
- Drugs that contain -static and -cidal
- ototoxcity drugs
- inhibits growth, lower dose
- kills, higher dose
- penicillin, macrolides, lincosamides
- amphoteracin, vaomycin, gentamycin
- -vir
- -mine
- -zine
- -mycin
- exception to mycin
- antivirals
- 1st generation antihistamine
- 2nd generation antihistamine
- lincosamide
- aminoglycoside, know gentamycin
- Liver Toxicity
- Renal Toxicity
- Creatnine BUN
- Ketoconazole, RTI, Protease, INH, Tetracycline, Macrodantin (LIVER)
- Amphoteracin HIGH, Gentamycin, Acyclovir, Tetra, Vanomycin(NEPHR)
- Peptides, acycloir, gentamycin BUN
- GI upset
- Peripharl Neruopathy
- This is not an antibiotic
- Narrow Spectrum drug
- Ampicillin, Fluroquinolones, MAcrodantoin, Erythromycin
- INH
- Pyridium
- Aminoglycoside
- Take with food
- Empty stomache
- Food or no food
- erythromycin, flagyl, macrodantoin
- penicillin, INH, Tetra
- ampicillin- watch CITRUS
- First generation antihistamine
- 2nd generation antihistamine
- SE of Oral antihistamine
- Most effective antiasthma drug
- Sedating
- Non-sedating
- anticholinergic- dry mouth, constipation, urinary retention
- glucocorticoids
- Long term, prophylaxis Asthma prevention
- Side effects of glucocorticoid inhaler
- Why do you rinse your mouth with glucocorticoid inhaler?
- Used with glucocorticoid inhaler?
- Cromolyn
- Glucocorticoid inhaler, Long Acting inhaled Beta 2 agonist, Comolyn
- throat, dry mouth, cough
- oral fungal infections
- Long acting Beta 2 Agonist
- Mast cell wall stabilixer, prevents mediators
- Acute Asthma treatment
- SE of oral glucocorticoids
- How can you take Selective Beta 2 Receptor?
- Categories for Beta 2 Agonist/Bronchodilator Agents
- Oral glucocorticoids, Selective Beta 2 Receptor, Short Acting inhaled Beta 2
- peptic ulcer, T.E., must taper
- nebulizer, inhaler, systemic effects w/ oral
- methyxanthines, anticholinergics
- What part does asthma effect?
- Types of antiinfammatory agents
- What does cromolyn do?
- What is a leukotriene
- Singulair
- Lower respiratory tract
- Glucocorticoids, cromolyn, leukotriene modifiers, IgE antagonist
- Stabilize Mast Cell Wall
- chemical mediator for inflammatory response
- Leukotriene antagonist, bronchodilation
- Asthma.Methylxanthin derivative agents
- Methylxanthin agents cause…
- Theophylline
- Theophylline action
- How do you give it?
- Aminophylline, Theophyline, Caffeine
- bronchodilation, CNS excitation, Vasodilation, Cardiac stimulus, diuresis
- Too many SE, narrow window,
- relaxes smooth muscle of bronchi
- IV or oral
- Aminophyline
- Anticholinergic for Asthma (COPD off Label)
- Action
- SE of Ephedrine
- SE of Pseudoephedrine
- Salt Theophylline, give slow–>hypotension/death. incompatible
- Atrovent(inhaled), Tiotropium
- Bronchodilator, block pns
- HTN, Dysrrythmias, MI, Stroke, Seizure, hyperglycemia, OFF MARKET
- Cardiovasscular collapse, HTN, Seizure
- Antitussive, Upper Respiratory Tract, cough
- Dextromethorphan
- Diphenydramine
- Non drowsy, antihistamine for hay fever
- Relief of non productive cough, medulla, drowsiness
- Non-narcotic, OTC, cold remedy
- also a antihistamine, help to sleep, allergy, cold, cough
- Fexofenadine/Allegra
Allergic Rhinitis, MAST CELL
- Histamines
- Leukotrines
- Prostaglandins
- vasodilate, itching, mucus, inc cap perm, bronchoconstrict
- asthma, bronchoconstrict, mucus, airway, edema
- vasodilate, fever, PAIN, inc cap permeability
- Glucocorticoids and allergies
- First line thearpy for allergic rhinitis
- What else cane you use to treat allergy?
- Antihistamine prophylaxxis allergy treatment
- dec inflam, inhibit prostaglandin relese, INTRANASAL MOST effective
- intransal glucs, oran/intranasal antihis
- sympathomimetics
- Histamine 1, common, sneeze, rhinorrhea, itchy nose. DOESN NOT REDUCE NASAL CONGEST
- Decongestants stimulate which recptor?
- Action
- Phenylphine, Oxymetazoline, Sudafed Usage, Sympathomimetics
- Respiratory and Obstructive Complications
- Alpha 1 Receptor
- HTN, vasoconstriction capillaries in the nuse
- use for 5 days only, rebound congestions
- beta 2 adrenergic agonist
- How C/S test can decrease resistance
- misues of antibiotics what percent?
- Vanomycin
- Side effects of Vanomycin
- Prevention for antibiotic use
- Actual microbe specific to antibiotic
- 50% use in hospital that don’t need them
- Effective against MRSA (avoid use), GLYCOPEPTIDE
- redman syndrome, slow iv or pump
- vaccines, limit catheters, c/s before, handwashing
- Gen Broad spectrum antibiotics
- Penicillin
- Most common type of penicillin
- Allergy alternative to Penicillin
- Macrolide
- Thromycin
- Beta lactam, interfere with cell wall, LYSE
- Amoxicillin, low resp infection, skin infection,
- Erythromyciin, Macoline
- supress protein synthesis, bacteriostatic
- Antibacterial Categories
- How do you treat allergic reactions?
- Gram+
- Gram -
- Mycostatin
- Penicillins, cephlosporins, macrolides, lincosamides, sulfonamides, glycopeptides, aminoglycoside, tetra, fluroquinolones, antTB, antifungal
- antihistamins, bronchoDILATORS, ephinephrine
- thick wall, purple (cocci)
- thin wall, violet, neisseria
- antifungal, candidiasis, leakage membrane
- Lincosamides,
- Resemblence to Penicillin
- Penicillin resistance
- Penicillin patient education
- Cephalosporin
- inhibit protein synthesis, SE colitis, rash, antiacne
- cephalosporin
- Staph, MRSA, Methicillin (NOMARKET)
- reduce contraceptive, take entirety, stomatitis, vaginits, c/s before
- most common, less side effects, broad spectrum
- Tetracycline uses
- Adverse effects
- Why vitamin b6 and inh
- Flagyl action
- Alcoholic effects of flagyl
- Chlamydia, anthrax, cholera, lyme, ulcer, acne, pneumonia, rm spotted fever
- photo, discolr teeth, NO
- decrease peripheral neuropathy
- Impairs DNA function of bacteria, antibiotica, antiprotozoal
- causes disulifiram, for alcoholics
- Flagyl Use
- Colorectal surgery
- Adverse effects
- Gentamycin what will you watch for?
- Administer Gentamycin how
- GI, GI, CNS, C.DIFF
- flagyl, prophylaxis
- dark urine,
- narrow window, urin output, balance, hearing
- IM IV
- Potent antibiotic
- Adverse effects
- Decrease risk of crystalluria
- What is fluroquinolones good for?
- Fluroquinolones, not 1st line treatment
- photo, gi, crystalluria
- increse fluid intake
- tissue penetration, respiratory tract infection, inhibit DNA synthesis.
- Antiseptic, antiinfective
- Baceter…
- Adverse Effect
- Pyridium and urine
- UTI’s, Macrodantin
- cidal, static
- peripheral neruopathy,dizzy, drowsy RUSTY URINE
- analgesic w/ antibiotic discolors urine. NOT ANTIMICROBIAL, take when symptoms are gone
- Sulfanomides
- What do sulfanomides treat
- Silvadene
- Action of sulf
- Bactrim, Septra, bronchitis too
- UTI-E.coli, otitis media, newborn eye prophylaxis
- Topical, for burns
- interefers with folic acid synthesis, -static
- Amphotericin B category
- administration
- Action of amph B
- Drug of choice for ringworm, alternative to ampho
- why have fungal infections increased?
- polyene, antifungal, RENAL, severe (mening in HIV patients)
- IV only
- binds to membrane allow leakage
- ketoconazole
- invasive procedures, immunosuppresants, broadspectrum antibiotics
- This is an antiretroviral agent used to treat HIV
- HAART
- Cocktail for HAART
- How long for use
- Adverse Effects
- AZT
- Highly Active Antiretrioviral Therapy
- 2 Rti’s with Protease inhibitor
- lifetime
- drug interaction, anemia neutropenia, anorexia,liver, lactic acidosis
HAART
- Action
- Safety
- Assess
- undetectable viral lode, improves CD4 count
- does not prevent trasnmission, need refular follow up exams
- hypersenstivity
Neurominidase inhibitors
- What does it treat
- when should you take it
- How does it treat?
- release of virus from infected cells
- within 48 hours of flu symptoms
- Inhibits the enzyme, may alter virus Particle
- Antiviral, Antiherpes
- Route
- action
- Treats
- Adverse effects
- acyclovir,
- Topical, oral IV (oral prevents recurrence)
- varicella zoster, EBV, herpes
- gingival hyperplasia, encourage fluids, renal BUN
- AntiTB bacteria
- How is it transmitted
- Cell wall
- How long for treatment
- Approach
- Acid Fast Bacillus (rods)
- droplet
- Thick, resitat to penetration by antiinfectives
- 6-24 months
- Use combo drugs
- What is Isoniazide
- Action
- Route
- Labs
- SE
- prophylaxis antiTB
- inhibts mycobacterial cell wall synthesis and intereferes with metabolism
- First oral drug affective against TB
- Liver enzymes, Sputum samples morning
- Peripheral neuropathy b6
1. Expectorants drugs
- Define Expectorant
- Has both Adrenergic and Corticosteroid
- Robitussin,
- Liquefy secretions, increases respiratory tract fluid
- Symbicort, Advair