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Boards Prep > Pharm: Bootcamp > Flashcards

Pharm: Bootcamp Flashcards

1
Q

If a drug has less protein binding, how does that affect the drug?

A

Less duration of action

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2
Q

IF a drug has more protein binding, how does that affect the drug?

A

Longer duration of action

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3
Q

If a drug has a lower pKA, how does that affect the drug?

A

More rapid onset of action

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4
Q

If a drug has a higher pKA, how does that affect the drug?

A

More slow onset of action

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5
Q

What is the max recommended dose for Prilocaine?

A

600 mg

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6
Q

What 2 things should be administered in case of methemoglobinemia?

A

Vitamin C and methylene blue

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7
Q

Where in the brain does cocaine predominately exert its effect?

A

Nucleus accumbens

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8
Q

If a pt has a candida infection after being on Abx, what should you do?

A

Remove source of infection, discontinue Abx, clomitrazole troche

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9
Q

What med is used to treat Mucormycosis?

A

Amphotericin B

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10
Q

What type of agent should be taken as a prophylactic for a pt about to begin chemo?

A

Antifungal like Nystatin

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11
Q

What med inhibits fungal cytochrome P450 and inhibits cell membrane formation?

A

Fluconazole
-azoles

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12
Q

Which of the following medical conditions requires antibiotic prophylaxis?
Tetralogy of Fallot
Calcific aortic stenosis
History of total joint replacement
Mitral Valve Prolapse

A

Tetralogy of Fallot

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13
Q

Which of the following medical conditions requires antibiotic prophylaxis?

A

Inhibits synthesis of an integral part of hte fungal cell membrane

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14
Q

What should be used to treat angular chelitis?

A

Nystatin and triamclione cream

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15
Q

Which ion determines binding affinity of agonists and antagonists to the mu-opioid receptor?

A

Sodium

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16
Q

Each of the following are appropriate mu-receptor agonists to provide analgesia for this patient EXCEPT one. Which is the EXCEPTION?
Nalbuphine
Hydrocodone
Tramadol
Codeine

A

Nalbuphine: mixed agonist/antagonist

17
Q

Which of the following can be a potential side effect of morphine?
Mydriasis
Pneumonia
HTN
Increased wakefulness

A

Pneumonia

18
Q

Codeine is the prodrug for what analgesic medication?

A

Morphine

19
Q

Codeine is ineffective in patients with which of the following comorbidities?
CHF
DM
Kidney failure
Liver failure

A

LIver failure

20
Q

All of the following are medicinal uses of marijuana targeting the cannabinoid receptors EXCEPT one. Which is the EXCEPTION?
REducing schiz episode
Decreasing N and V in chemo pts
Alleviating chronic pain
Decreasing muscle spasm during seizures

A

Reducing schiz episodes

21
Q

Each of the following is a possible symptom of the patient’s recreational drug use EXCEPT one. Which is the EXCEPTION?
Paranoia
Xerostomia
Bradycardia
Altered sense of time

A

Bradycardia

22
Q

___ drugs are contraindicated in pts with acute intermitten porphyria

A

Barbituates

23
Q

What med out of lorazepam, midazolam, diazepam, and triazolam would be best to give an axious adult for a 1 hour appt?

A

Triazolam: short acting

24
Q

What is the MOA of carbamazepine?

A

Blocks Na channels

25
Q

Each of the following is a side effect of the patient’s medication: methylphenidate EXCEPT one. Which is the EXCEPTION?
Nervousness
Bradycardia
Weight loss
Sweating

A

Bradycardia

26
Q

What medication most likely has contributed to the patient’s current findings?

Reports moderate-severe muscle pain and darkened, reddish urine

A

Statins

27
Q

Which of the following is the mechanism of action of a statin?

A

Reduces liver production of cholesterol

28
Q

All of the following are potential side effects of furosemide (Lasix®) EXCEPT one. Which is the EXCEPTION?
Hypokalemia
Hearing loss
Hypercalcemia
Interstitial nephritis

A

Hypercalcemia

29
Q

Persistent dry cough is a side effect of which of the following drugs?
Lisinopril
Triamterene
Furosemide
Hydrochlorothiazide

A

Lisinopril

30
Q

MOA of bisphosphonates

A

Inhibits osteoclasts

Boards Prep (21 decks)

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