Pharm: Bootcamp Flashcards
If a drug has less protein binding, how does that affect the drug?
Less duration of action
IF a drug has more protein binding, how does that affect the drug?
Longer duration of action
If a drug has a lower pKA, how does that affect the drug?
More rapid onset of action
If a drug has a higher pKA, how does that affect the drug?
More slow onset of action
What is the max recommended dose for Prilocaine?
600 mg
What 2 things should be administered in case of methemoglobinemia?
Vitamin C and methylene blue
Where in the brain does cocaine predominately exert its effect?
Nucleus accumbens
If a pt has a candida infection after being on Abx, what should you do?
Remove source of infection, discontinue Abx, clomitrazole troche
What med is used to treat Mucormycosis?
Amphotericin B
What type of agent should be taken as a prophylactic for a pt about to begin chemo?
Antifungal like Nystatin
What med inhibits fungal cytochrome P450 and inhibits cell membrane formation?
Fluconazole
-azoles
Which of the following medical conditions requires antibiotic prophylaxis?
Tetralogy of Fallot
Calcific aortic stenosis
History of total joint replacement
Mitral Valve Prolapse
Tetralogy of Fallot
Which of the following medical conditions requires antibiotic prophylaxis?
Inhibits synthesis of an integral part of hte fungal cell membrane
What should be used to treat angular chelitis?
Nystatin and triamclione cream
Which ion determines binding affinity of agonists and antagonists to the mu-opioid receptor?
Sodium
Each of the following are appropriate mu-receptor agonists to provide analgesia for this patient EXCEPT one. Which is the EXCEPTION?
Nalbuphine
Hydrocodone
Tramadol
Codeine
Nalbuphine: mixed agonist/antagonist
Which of the following can be a potential side effect of morphine?
Mydriasis
Pneumonia
HTN
Increased wakefulness
Pneumonia
Codeine is the prodrug for what analgesic medication?
Morphine
Codeine is ineffective in patients with which of the following comorbidities?
CHF
DM
Kidney failure
Liver failure
LIver failure
All of the following are medicinal uses of marijuana targeting the cannabinoid receptors EXCEPT one. Which is the EXCEPTION?
REducing schiz episode
Decreasing N and V in chemo pts
Alleviating chronic pain
Decreasing muscle spasm during seizures
Reducing schiz episodes
Each of the following is a possible symptom of the patient’s recreational drug use EXCEPT one. Which is the EXCEPTION?
Paranoia
Xerostomia
Bradycardia
Altered sense of time
Bradycardia
___ drugs are contraindicated in pts with acute intermitten porphyria
Barbituates
What med out of lorazepam, midazolam, diazepam, and triazolam would be best to give an axious adult for a 1 hour appt?
Triazolam: short acting
What is the MOA of carbamazepine?
Blocks Na channels
Each of the following is a side effect of the patient’s medication: methylphenidate EXCEPT one. Which is the EXCEPTION?
Nervousness
Bradycardia
Weight loss
Sweating
Bradycardia
What medication most likely has contributed to the patient’s current findings?
Reports moderate-severe muscle pain and darkened, reddish urine
Statins
Which of the following is the mechanism of action of a statin?
Reduces liver production of cholesterol
All of the following are potential side effects of furosemide (Lasix®) EXCEPT one. Which is the EXCEPTION?
Hypokalemia
Hearing loss
Hypercalcemia
Interstitial nephritis
Hypercalcemia
Persistent dry cough is a side effect of which of the following drugs?
Lisinopril
Triamterene
Furosemide
Hydrochlorothiazide
Lisinopril
MOA of bisphosphonates
Inhibits osteoclasts
