Pharm 33

Question 1

Lipoprotein profile
SATA 4

Answer 1

Total cholesterol
LDL (harmful)
HDL ( protective)
Triglycerides

Question 2

Cholesterol range & triglycerides range are knows as hyperlipidema & associated with atherosclerosis

Answer 2

Above 240
Above 150

Question 3

Desirable total cholesterol level

Answer 3

Less than 200

Question 4

Optimal LDL cholesterol level

Answer 4

Less than 100

Question 5

High HDL cholesterol

Answer 5

60 and above

Question 6

Normal triglycerides level

Answer 6

Less than 150

Question 7

___ is Considered to the a major contributor in the development of heart disease particularly __ & ___

Answer 7

Atherosclerosis
Heart attacks & strokes

Question 8

Two lipids in our blood

Answer 8

Cholesterol
Triglycerides

Question 9

Saturated fat and cholesterol in foods ___ &__\ levels

Answer 9

Raise total & LDL

Question 10

Increased weight can make __ levels go ___ & ___ level go ___

Answer 10

LDL - up
HDL - down

Question 11

Increased physical activity helps to ___ & ___

Answer 11

Lower LDL
Raise HDL

Question 12

Two activities of statins

Answer 12

Inhibit manufacturing of cholesterol
Promoting breakdown of cholesterol

Question 13

2 uses for statin drugs

Answer 13

Treatment of hyperlipidemia
Primary prevention of coronary events (including strokes)

Question 14

Adverse reactions of statins (4)

Answer 14

Headache
Insomnia
Constipation
Nausea

Question 15

Drugs that cause increased risk of myopathy
SATA (4)

Answer 15

Clarithromycin
Amiodarone
Niacin
Verapamil

Question 16

Interaction with statins & warfarin

Answer 16

Increased anticoagulant effect

Question 17

Bile acid resins are used to treat

Answer 17

Hyperlipidemia in clients who do not have an adequate response to diet and exercise

Question 18

Adverse reaction to bile acid resins

Answer 18

Increased bleeding tendencies related to vitamin K malabsorption
Vitamin A & D deficiency

Question 19

Bile acid resins are used cautiously in

Answer 19

Diabetes
Liver/peptic ulcer
Kidney disease
Pregnancy/lactation

Question 20

Statins are contraindicated in
SATA (3)

Answer 20

Hypersensitivity to drugs
Serious liver disorders
Pregnancy/lactation

Question 21

When administration with bile acid resins, a decreased serum level or decrease GI absorption of the following drugs may occur

Answer 21

NSAIDs
Glipizide
Propranolol

Question 22

Forbid acid derivatives are contraindicated in

Answer 22

Hypersensitivity to drug
Significant hepatic or renal dysfunction
Primary biliary cirrhosis
(May increase the already elevated cholesterol)

Question 23

Increases the excretion of cholesterol in the feces and reduces the production of triglycerides by the liver, thus lowering serum lipid levels

Answer 23

Gemfibrozil

Question 24

Used as adjunctive therapy for lowering very high serum triglyceride levels in clients who are at risk for pancreatitis

Answer 24

Niacin

Question 25

Bile acid resins may interfere with the digestion of ___ and prevents the absorption of ___ & ___

Answer 25

Fats Fat soluble vitamins Folic acid

Question 26

Statins (3) (2 trades) (1 use)

Answer 26

Atorvastatin(Lipitor)- hyperlipidemia Loevastatin Simvastatin(Zocor)

Question 27

Bile acid resins (3)

Answer 27

Cholestyramine Colestipol Colesevelam

Question 28

Fibric acid derivatives (2) (1trade)

Answer 28

Fenofibrate Gemfibrozil (Lopid)

Question 29

Miscellaneous preparations (1) (use) (adverse reactions)

Answer 29

Ezetimibe- primary hypercholesterolemia Diarrhea, abdominal pain