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Pharm > PGAs > Flashcards

PGAs Flashcards

1
Q

What is the typical percentage of Latanoprost (Xalatan)?

A

0.005%

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2
Q

What is the typical percentage of Bimatoprost (Lumigan)?

A

0.03%

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3
Q

What is the typical percent of Travoprost (travatan )?

A

0.004%

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4
Q

What is the preservative in Travatan Z?

A

Sofzia - instead of BAK

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5
Q

What is the MOA of PGAs?

A

Act on PFG2a receptors on the ciliary muscle, reduces neighboring collagen, decreasing resistance in the uveoscleral meshwork

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6
Q

What time of day is recommended for dosing PGAs?

A

Bedtime

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7
Q

Why is bedtime dosing recommended for PGAs?

A

Allows for better diurnal control and has a daytime peak effect

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8
Q

What are the contraindications for PGAs?

A

Pts at risk for CME
Cataract surgery post-op
Active inflammation
Previous HSK

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9
Q

What are the common side effects of PGAs?

A 
Iris heterochromia (permanent)
Skin pigmentation
Growth of eyelashes
Conj hyperemia
Pruritis
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10
Q

Pruritis is worst with which PGA?

A

Lumigan

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11
Q

Conj hyperemia is worst with which PGA?

A

Lumigan

-best with Xalatan

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Pharm (13 decks)

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