Peripheral neuropathy Flashcards
symptoms of peripheral neuropathy
paraesthesia weakness in legs sensory loss falls, unsteady dizzy tachycardic impair digestion
definition of paraesthesia
burning pain, numb
associated symptoms of peripheral neuropathy
injuries
ulcers
infections
hot/cold
differential diagnosis for peripheral neuropathy
cerebellar disorder syringo myelia - cyst in spinal cord GB botulism alcohol, diet, drugs
pathology of peripheral neuropathy
demyleination axonal degeneration wallerian degeneration (trauma) compression infarction infiltration
3 categories of classification for peripheral neuropathy
mono or poly
axonal, demyelination, mixed
sensory, motor, senori-motor, autonomic neuropathy
related metabolic deficiencies
diabetes B12 lead poisoning alcohol B1 B12
B1 deficiency
beriberi
cardiac failure
cardiomyopathy
B12
decrease in thyroid, kidney, liver
causes of peripheral neuropathy
- diabeteic neuropathy
- toxins - alcohol, drugs, liver/kidney failure, diet
- drugs - phenytoin, metronidzole, amodiarone
- autoimmune - RA, GBS
- trauma
- other disease - infection, CNS, genetic, frericks ataxia
example of mono peripheral neuropathy
carpaal tunnerl
sciatic nerve
ulnar/radial palsy
unilateral foot drop
example of poly peripheral neuropathy
celiac
diabetes
hep
charcot-marie tooth
peripheral neuropathy investigations
FBC, LFT, UE, B12, Folic acid, ESR, CRP, HBA1C. uringe, glucose, protein
ANA, ANCA
nerve conduction studies
EMG
