epilepsy Flashcards

1
Q

what is epilepsy

A

recurrent spontaneous seizures

persistent and prolonged

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2
Q

2 features of seizure

A

prodrome: change in mood/behaviour

aura

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3
Q

causes of epilepsy

A
idiopathic
structural 
TB
trauma
stroke
increasedd ICP
hemorrhage
alcohol 
drugs
hypoglycemia
hypoxia
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4
Q

what structural defects cause epilepsy - 4

A

cortical scarring
development
leisons
scarring

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5
Q

what is a partial seziure - 2

A

1 part of hemisphere

structural disease

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6
Q

2 types of partial seziures

A
  1. simple

2. complex

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7
Q

what is a simple partial seizure

A

awareness unimpaired

no post ictal symptoms

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8
Q

what is a complex partial seizure

A

awareness impaired

post ictal confusion

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9
Q

what are the two types of primary generalised seizures

A

absence

tonic clonic

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10
Q

what is a primary generalised absent seizure

A

less than 10 second pauses

childhood

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11
Q

what is a primary generalised tonic clonic - 4

A

loss of consciousness
stiff limbs
post ictal confusions
drowsiness

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12
Q

what is myoclonic symptoms

A

sudden jerk

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13
Q

what are the DDx for epilespy - 4

A

vasovagal syncope
arrythmia
hypoglycemia
psychogenic/NEAD

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14
Q

what is an initial stage management

A

ACDE, O2, IV access, IV fluids
BM, VBG, bloods, CT
Hx
general exam

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15
Q

what are the investigations for seizure

A
bloods
ecg
urine - pregnancy
ct/mri
eeg
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16
Q

what are more common - provoked or non provoked

A

non provoked

17
Q

when do you start a first time seizure person on an antiepileptic? 4 reasons

A
  1. risk of reoccurance
  2. reoccurance is unacceptable
  3. definitive epileptic on EEG
  4. brain damage on leison
18
Q

3 classes of anticonvulsants

A

NA
Ca
GABA enhancement

19
Q

examples of Na - 3

A

phenytoin
carbamazepine
lamotrigine

20
Q

examples of Ca - 1

A

ethosuxamide

21
Q

examples of gaba enhancment - 3

A

benzo
gabapentin
vigabatrin

22
Q

what is a contraindication of AED

A

contraception pill

23
Q

what is status epilepsy

A

more than 5 mins

24
Q

what can status epilepsy lead to

A

hypoxia

25
Q

AED SE - 4

A

drowsy
hair loss
agitation
headache

26
Q

who is more likely for status epilepsy - 4

A

learning disability with structural brain change
encephalitis
stroke
brain tumour

27
Q

what can cause odd behaviour

A

encephalitis

28
Q

what is increased in bacterial

A

neutrophil

29
Q

what is increased in viral

A

lymphocyte

30
Q

what does SUDEP mean

A

sudden death by epilepsy