Perio 3 quiz 1 Flashcards
AAP
AA, P.gingivalis, T.forsythia
(Scythian has A Agressive gingivalis)
Red complex
T.denticola, P.gingivalis, T. Forsythia
(Synthia drinks a Red cola and gets gingivalis)
ANUG or ANUP
T.denticola, P.intermedia, F.neucleatum
Pregnancy
P.intermedia, c. Rectus
(After intermediate the baby comes out of the rectus)
Aggressive
A.A, P.gingivalis
Cytokines
Collagen (gingiva, PDL), bone loss
Prostaglandin E
MMP secretion, bone resorption
MMP
Breakdown of collagen, matrix in gingiva, PDL and alveolar bone
RANKL-RANK
Osteoclastic activity
Initial lesion-sub clinical
2-4 days
Early lesion- Gingivitis
4-7days
Established lesion-Gingivitis
21days or more
Advanced periodontist lesions
Periodontal pocket
Apical migration of JE
Alveolar bone loss
PDL loss
6 major ecosystems
-intraoral and supra gingival hard surface
- sub gingival regions adjacent to hard surface
-buccal palatal epithelium and floorof mouth epithelium
-dorsum of tongue
-tonsils
-saliva
Organic constituents
Polysaccharides, proteins, glycoproteins, lipid material, DNA
Inorganic components
Calcium, phosphorus, small amounts of sodium, potassium, fluoride
Apical dominant in
Spirochetes, cocci, rods
Coronal
Filaments
Increase in steroid hormones cause an increase in
P.intermedia in sub gingival
P.gingivalis is required for
Adhesion and formation
3 keystone pathogen mechanisms for p.gingivalis
-p.gingivalis manipulate the toll like receptor 4 response
-inhibit synthesis of interleukin 8 (local chemokine paralysis)
-interference with the complement system component of the innate immune system
Virulence factor
Promote colonization
Toxins and enzymes that degrade host tissue
Protect pathogenic bacteria from the host
