Pericaradial Disorders Flashcards

1
Q

What are the layers of the pericardium?

A

Outer fibrous = parietal pericardium

Inner serous= visceral pericardium

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2
Q

T/F: there is normally some fluid in the pericardial space

A

True

about 0.25ml/kg

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3
Q

What are acquired causes of pericardial effusion?

A
Neoplastic 
Idiopathic pericarditis 
Infectious
Cardiovascular 
Metabolic 
Toxic/coagulopathy 
Trauma
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4
Q

What are the congenital pericardial diseases?

A

Peritoneopericardial diaphragmatic hernia (PPDH)

Pericardial cyst

Pericardial defects

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5
Q

What is the most common pericardial disorder in dogs and cats?

A

Pericardial effusion

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6
Q

What type of fluid is usually present in a pericardial effusion of a dog?

A

Sanguineous (hemorrhagic)

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7
Q

As long as intrapericardial pressure is _________ than intracardiac pressure, diastolic filling is maintained

A

Lower

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8
Q

When intrapericardial pressure equals or exceeds intracardiac pressure, diastolic filling decreases resulting in _____________

A

Decreased stroke volume and cardiac output

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9
Q

What is a cardiac tamponade?

A

Pressure put on the heart by fluid in the pericardium

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10
Q

As CO falls due to cardiac tamponade, what occurs systemically?

A

Systemic venous pressure rises —> congestion and effusion

Can result in hepatomegaly, ascities, and pleural effusion

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11
Q

What is the signalment of animals with pericardial effusion?

A

Dogs > cat

Middle age to older
Large and medium breeds >small breeds
-golden retriever, GSD, lab, brachycephalic

Males>females

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12
Q

What is the main presenting complaint in dogs with pericardial effusion?

A

Collapse/weakness

-can have vomiting within the last 24/48hrs

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13
Q

What are clinical signs associated with chronic pericardial effusion?

A

Lethargy
Exercise intolerance
Decreased appetite
Abdominal distention (peritoneal effusion due to systemic congestion secondary to pleural effusion)

Respiratory signs also possible (large heart or pleural effusion)

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14
Q

How does the heart sound on auscultation if a pericardial effusion is present?

A

Muffled - significantly decreased intensity

Lung sounds may also be decreased in plural effusion is present

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15
Q

What is the heart rate, and how do the femoral pulses feel win animals with pericardial effusion?

A

High-normal heart rate

Weak femoral pulses

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16
Q

Jugular venous distention and hepatomegaly result from pericardial effusion as a consequence of?

A

Increased systemic venous pressure and congestion

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17
Q

If a tamponade is profound, arterial hypotension and hypoperfusion will be severe. What clinical signs would you observe?

A

Weakness
Depressed or dull mentation
Comatose
Cardiopulmonary arrest

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18
Q

What can confirm a suspect pericardial effusion diagnosis?

A

Thoracic FAST

  • evaluate right atrial wall for collapse=cardiac tamponade
  • evaluate for pleural and peritoneal effusion
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19
Q

If a cardiac tamponade is present, what treatment does this animal need ASAP?

A

Pericardiocentesis

—>patients with cardiac tamponade can “look good” but it is ALWAYS a life threatening condition and is an emergency

20
Q

What would you see on radiographs in a animal with pericardial effusion?

A

Markedly enlarged and globoid cardiac silhouette

- if PE is small volume, may be normal or only mildly increased

21
Q

Why is lactate increased in patients with pericardial effusion?

A

The body attempts to save BP before everything else

Low CO -> vasoconstriction to maintain BP—> hypoperfusion —> tissue damage and lactate

22
Q

What is electical alterans?

A

ECG with beat-to-beat variation in QRS amplitude

Due to heart moving location within the effusion

23
Q

What is the treatment for pericardial effusion?

A

Pericardiocentesis
Volume resuscitation with crystalloids

Antiarrhythmic therapy and indicated

Thoracocentesis if pleural effusion
Abdominocentesis if peritoneal effusion

24
Q

T/F: furosemide is the drug of choice for treating cardiac tamponade

A

FALSE

Diuretic treatment is contraindicated with cardiac tamponade
—> due to high intrapericardial pressure, the amount of blood into the heart is already decreased, you do not want to further decrease preload with a diuretic

25
What diagnostics should you do in a animal with pericardial effusion?
Coagulation profile —> rule out coagulopathy Minimum database Thoracic radiographs Fluid analysis and cytology of effusions Echo Staging with abdominal ultrasounds or CT (neoplastic cases)0
26
What is the most common cause of pericardial effusion?
Neoplasia (hemangiosarcoma
27
What is the most common location of hemangiosarcoma ?
Right atrium/auricle
28
T/F: metastasis are common with hemangiosarcoma
True —> lungs and spleen
29
What are the treatment options with hemangiosarcomas found at the heart bases?
Resection usually not feasible due to location Chemo /Radiaiton Yunnan Baiyao - Chinese herb with prothrombin properties Aminocaproic acid -antifibrinolytic
30
What is a chemodectoma?
AKA heart base tumor Tumor involving the chemoreceptor cells in the ascending aorta
31
What breeds are predisposed to chemodectoma?
Brachycephalic
32
What are clinical signs that are seen with chemodectoma ?
``` Exercise intolerance Syncope Dyspnea Cough Ascities ```
33
What cardiac neoplasms usually do not have a discrete mass?
Mesothelioma Lymphoma
34
T/F: arrhythmias are a potential complication of any cardiac tumor
True
35
What is idiopathic pericarditis?
Effusion that slowly develops (can be large volume) —> may have viral and immune-mediated etiology Disease response in 50% of dogs after initial treatment
36
What is the treatment of choice for recurrent pericardial effusion?
Subtotal pericardiectomy
37
What is the disease name where the parietal/visceral pericardium becomes fibrotic?
Constrictive pericarditis
38
What is the pathophysiology of constrictive pericarditis?
Fibrous pericardium is stiff —> limits diastolic filing —> systemic venous pressure rises —> R sided CHF
39
What are causes of constrictive pericarditis?
Chronic inflammation - idiopathic - foreign body Fungal Idiopathic
40
What is the treatment of choice for constrictive pericarditis?
Subtotal pericardectomy | -corticosteroids used in some idiopathic cases
41
What would your DDX be for hemorrhagic PE?
Coagulopathy Left atrial tear Trauma
42
What is your DDx for transudate PE?
``` Hypoalbuminemia CHF Vasculitis PPDH Pericardial cyst ```
43
What is your DDX for exudative PE?
Infectious - migrating foreign body (nidus) - bacterial - fungal - viral - protozoal
44
How do pericardial effusions usually appear in cats?
Small volume and chronic Tamponade is rare
45
What is the most common cause of PE in cats?
Congestive heart failure 2nd most common is neoplasia (lymphoma, adenocarcinoma, thymoma, mesothelioma)