Neuro - Pelvic Limb Conditons Flashcards
What disease occurs due to degeneration of axons and their myelin sheaths in the thoracolumbar spinal cord?
Degenerative myelopathy
Degenerative myelopathy mainly affects what animals?
Large and giant breed dogs
GSD, boxer, corgi, Siberian husky, cheasapeake bay retrievers and Rhodesian ridgebacks
Is degenerative myelopathy an acute or chronic onset disease
Chronic - over 6 to 20 months
GSD, 8yrs old
Knuckling, dragging toes, crossing legs when walking , ataxia of pelvic limbs. UMN signs. No hyperesthesia
What would be on your DDX?
Degenerative myelopathy
Lumborosacral degenerative stenosis -> pain on tail jack test
Thoracolumbar intervertebral disk disease -> can be associated with pain due to stretching on longitudinal ligaments
Diskospondylitis -> other signs of infection (pyrexia, depression, and weight loss)
Vertebral and spinal neoplasia
Fibrocartiaginous emboli -> non painful but usually lateralizing
Vertebral fracture/luxation -> history of trauma, spinal hyperesthesia, anesthesia, decreased voluntary motor activity, crepitus, Schiff-Sherrington
How do you clinically diagnose degenerative myelopathy??
Signs
Exclusion of inflammatory and compressive causes
Myelin based protein
What is the treatment for degenerative myelopathy?
None
Good nursing care and intensive physiotherapy can give the animal a few more months
What disease results from an instability of th L7/S1 area and can cause spinal cord compression?
Lumbosacral degenerative stenosis/Lumbosacral malarticuation-malformation(instability)/ cauda equina syndrome
T/F: in lumborosacral degenerative stenosis, compression of the spinal cord results in LMN signs in the femoral, sciatic, and pudendal nerves
False
Femoral nerve is spared -> retain ability to flex hip
LMN-sciatic and pudendal -> inability for flex/extend hock and urinary/fecal incontinence
T/F: in lumbosacral degenerative stenosis, there is no disc degeneration, but changes in ligaments and articulation facets
True
What is the signalment of dogs with cauda equina syndrome ?
Large breed dogs, especially working dogs.
GSDs and Border collies
5-8yrs
Border collie 6yr old
Lumborosacral pain
Difficulty rising and negotiating stairs
Decreased extension of the hock
Flaccid tail with pain elicited on tail jack test
What is your top DDX?
Lumborosacral degenerative stenosis
What tests would you do to support a suspected diagnosis of cauda equina syndrome?
Radiographs
Myelography can confirm compression, but most dogs the subarachnoid space ends and L6/L7
What is the treatment for lumbosacral degenerative stenosis ???
Medical management - muscle relaxants/tramadol/pred (good results but often signs recur when exercise levels increase)
Lumbosacral dorsal laminectomy and removal of ligaments and bone generating pressure on nerves
T/F:: in most breeds, there is almost complete replacement of the annulus fibrosis with fibrocartilage by 7-8yrs of age
True
Dorsal displacement of the nucleus pulposus can result in stretch of the _________________ ligaments
Dorsal longitudinal
What is a Hansen type 1 disc disease
Explosive extrusion of nucleus pulposus material into spinal canal
Chondrodystrophic breeds- Dashshunds, Pekingese, Welsh corgi, Beagles, Bassets, and Cocker Spaniels
And poodles
What is a Hansen type 2 disc disease? What type of dogs does it occur in?
Small tears appear in he annulus fibrosis and a slow protrusion of the nucleus pulposus
Large breed dogs