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PSIO469 - Repro > Performance Enhancing Drugs > Flashcards

Performance Enhancing Drugs Flashcards

1
Q

Stanozolol (Winstrol)

A

Synthetic steroid derived from testosterone

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2
Q

Anabolic effects of testosterone

A
  • Increased skeletal muscle mass
  • Increased RBC production
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3
Q

Characteristics of anabolic effects of testosterone are often associated with…

A

strength and endurance

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4
Q

Steroids have to be dissolved in

A

oil

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5
Q

Androgenic effects of testosterone

A
  • Increased libido
  • Facial hair growth
  • Deepening of voice
  • Growth and development of seminal vesicles and prostate gland
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6
Q

Characteristics of androgenic effects of testosterone are often associated with…

A

masculinization

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7
Q

Adverse effects from anabolic-androgenic steroid use in the bones

A

Premature closure of epiphysis in children (stunted growth)

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8
Q

Adverse effects from anabolic-androgenic steroid use in breast tissue

A

Gynecomastia (abnormal breast growth) in males

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9
Q

Adverse effects from anabolic-androgenic steroid use in the cardiovascular system

A
  • Increased risk of MI or stroke
  • Raised LDL (bad) and lowered HDL (good)
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10
Q

Adverse effects from anabolic-androgenic steroid use in the CNS

A
  • Increased aggression
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11
Q

Adverse effects from anabolic-androgenic steroid use in hair

A
  • Hirsutism (male-pattern hair growth) in women
  • Accelerated male-pattern baldness in men (DHT damages hair follicle)
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12
Q

Adverse effects from anabolic-androgenic steroid use in the liver

A
  • Impaired function (hepatoxicity from orally active steroids)
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13
Q

Adverse effects from anabolic-androgenic steroid use in the skin

A
  • Cystic acne
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14
Q

Adverse effects from anabolic-androgenic steroid use in vocal cords

A
  • Deepening of voice in females
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15
Q

Adverse effects from anabolic-androgenic steroid use in the reproductive system

A
  • Suppression of gonadal steroidogenesis
  • Testicular atrophy
  • Abnormal prostate growth
  • Amenorrhea in females
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16
Q

Amenorrhea

A

Absence or cessation of menstrual periods

17
Q

Hirsutism

A

Male-pattern hair growth

18
Q

Routes of steroid drug administration

A
  • Oral
  • Injection
  • Pellet
  • Transdermal (patch/gel)
  • Sublingual troche
  • Nasal spray
  • Intra-vaginal
19
Q

First-pass effect

A

Phenomenon of drug metabolism where concentration of orally administered pill is greatly reduced before it reaches systemic circulation

20
Q

Four potential systems of the first pass effect

A
  1. Gut wall enzymes
  2. Gastrointestinal lumen enzymes
  3. Bacterial enzymes
  4. Hepatic enzymes
21
Q

The ________ carries blood from the digestive tract to the liver.

A

Hepatic portal vein

22
Q

High index of medication

A

More anabolic

PSIO469 - Repro (18 decks)

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