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Pharmacology > Penicillin > Flashcards

Penicillin Flashcards

1
Q

Penicillin G and Penicillin V

A

Natural Penicillin

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2
Q

Natural Penicillin coverage

A

primarily gram positive (staph, strep enterococci), little gram negative (N. gonorrhea and N. meningitis), gram positive anaerobes

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3
Q

Natural Penicillin use

A

syphillis mainly

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4
Q

Why don’t we use natural penicillin anymore?

A

too much resistance

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5
Q

Dicloxacillin
Nafcillin
Oxacillin
Methicillin

A

Synthetic PCN

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6
Q

Synthetic PCN coverage

A

primarily gram positive and MSSA/MSSE

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7
Q

Synthetic PCN USE

A

MSSA infections including endocarditis

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8
Q

Amoxicillin

Ampicillin

A

Amino PCN

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9
Q

Amino PCN coverage

A

PCN with added gram negative (e. coli, p. mirabilis, h. flu); VRE( ampicillin)

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10
Q

What does ampicillin cover?

A

VRE

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11
Q

Amino PCN use

A

otitis media, UTI, Meningitis

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12
Q

Augmenting
Unsay
Zosyvn
Timentin

A

Beta lactam and beta lactamase inhibitor

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13
Q

Beta lactam and beta lactase inhibitor coverage

A

amino PCN + beta lactam producing strains

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14
Q

What are beta lactam producing strains

A

MSSA, h. flu, E. coli, m. catarrhalis, P. mirablis

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15
Q

What does Unasyn treat

A

acinetobacter

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16
Q

What treats P. aeroginosa

A

zosyn and timetin

17
Q

Beta lactam and beta lactase inhibitor use

A

broad empiric coverage, hospital acquired infection, b-lactamase producing organisms

18
Q

Why do we add beta lactam

A

to enhance and overcome resistance and enhance spectrum of activity

19
Q

ADR for PCN

A

GI (overcome with food), hypersensitivity and possibility for secondary infections

20
Q

ADR for nafcillin

A

neutropenia

21
Q

ADR for oxacillin

A

hepatitis

22
Q

What drug to use if hypersensitivity

A

aztreonam unless allergic to ceftazidime

Pharmacology (12 decks)

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