Cephalosporin Flashcards

1
Q

cefalzolin
cephalexin
cefadroxil

A

first generation

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2
Q

cefurixime
cefaclor
cefprozil

A

second generation 2A

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3
Q

cefoxitin

cefotetan

A

second generation 2B

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4
Q

cefotaxime
cetriaxone
cefixime
cefpodoxime

A

3rd gerenation anti-pneumoniae

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5
Q

ceftazidime

A

3rd generation anti pseudomonas

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6
Q

cefepime

A

4th generation

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7
Q

ceftarolin

A

5th generation

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8
Q

first generation cover

A
gram positive (staph; MSSA and strep)
gram negative (e.coli, proteus, klebilla)
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9
Q

first generation use

A

skin and soft tissue; uti

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10
Q

second generation 2a cover

A

gram positive staph and strep

beta lactase producing

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11
Q

second generation 2a use

A

respiratory tract infection

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12
Q

second generation 2b cover

A

improved gram negative

anaerobic coverage

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13
Q

second generation 2b use

A

abdominal infections and mixed infections

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14
Q

3rd generation cover

A

more gram negative and less gram positive

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15
Q

third generation use

A

community acquired pneumonia and meningitis

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16
Q

forth generation coverage

A

expanded gram negative, no anaerobic, little gram postive

17
Q

forth generation use

A

hospital acquired infections (pneumonia)

18
Q

fifth generation coverage

A

gram positive (staph, strep, MRSA and VRE)

gram negative (e.coli, klebsiella, h. flu)

19
Q

fifth generation use

A

community acquired pneumonia and skin and soft tissue

20
Q

ADR of cephalosporin

A

hypersensitive like PCN and cross reactive with PCN and CPN