aminoglycosides Flashcards
1
Q
AMG
A
gentamicin
tobramycin
amikacin
streptomycin
2
Q
AMG coverage
A
primarily gram negative, aerobic (pseudomonas)
synergy against gram positive
no aerobic and atypical
3
Q
AMG use
A
UTI, hospital acquired infections, endocardidtis
4
Q
Which drugs for hospital-acquired infections
A
ampicillin and gentamicin
5
Q
which drugs for endocarditis
A
streptomycin and beta lactam
6
Q
ADR
A
nephrotoxicity and ototoxicity and neuromuscular blockade
7
Q
what does post-antibiotic effect mean?
A
residual bactericidal activity persists even after concentration has fallen below MIC
8
Q
AMG kinetics
A
poor penetration into organs
renal fun for dosing interval
