Monobactam and Carbapenem Flashcards
1
Q
Monobactam
A
Aztreonam
2
Q
Aztreonam coverage
A
gram negative aerobics, including pseudomonas
3
Q
Aztreonam use
A
patients with severe beta lactic allergy
4
Q
When don’t you use Aztreonam
A
when patients have allergy to ceftazidime because same R side chain
5
Q
Aztreonam ADR
A
N/V/D
hypersensitivity
acute hepatitis
neutropenia
6
Q
carbapenem
A
imipenem/cilastatin
meropenem
ertapenem
doripenem
7
Q
carbapenem coverage
A
Gram positives: staph, strep, E. faecalis (except ertapenem)
Gram negatives: including P. aeruginosa (except ertapenem)
Anaerobes
8
Q
Carbapenem use
A
Infections caused by resistant organisms (drug of choice for ESBL)
9
Q
Carbapenem ADR
A
Seizures, GI, Headache
10
Q
What are carbapenem cross sensitive with?
A
PCN
11
Q
what drug causes seizures
A
imipenem
12
Q
What is entrapenem coverage mainly?
A
enterobactericae
