Penicillin Flashcards
Natural penicillins
- Penicillin G
- Penicillin V
Antistaphylococcal penicillins
- Methicillin
- Cloxacillin, dicloxacillin
- Nafcillin
- Oxacillin
Aminopenicillins
- Ampicillin
- Amoxicillin
Antipseudomonal penicillin
Carboxypenicillins – Carbenicillin, Ticarcillin
Ureidopenicillins – Piperacillin, Mezlocillin
Gram (+) cocci
- Streptococcus pneumoniae*
- Streptococcus pyogenes
- Viridans streptococci* group
Gram (+) bacilli
Bacillus anthracis
* Corynebacterium diphtheriae
Gram (-) cocci
Neisseria gonorrhoeae
* Neisseria meningitidis
Spirochetes
Treponema pallidum
* Treponema pertenue
Anaerobic organism
Clostridium perfringens
Antistaphylococcal penicillins
Methicillin (no longer used)
Oxacillin, Cloxacillin,Dicloxacillin
Nafcillin
Combination of penicillin with
B-lactamase inhibitors
a. Amoxicillin + clavulanic acid (po, i.v.)
b. Ampicillin + sulbactam (i.v., i.m.)
c. Piperacillin + tazobactam (i.v.)
Treatment of penicillin induced hypersensitivity reactions
Adrenaline 0.3–0.5 mL of 1:1000 solution (1 mg/mL) IM
* Inj. hydrocortisone 100–200 mg intravenously
* Inj. pheniramine 45 mg intramuscularly/intravenously
* Intravenous fluids
mechanism of penicillin resistance
n
MOA penicilin
n
penicilin G uses
n