neurodegenerative disorders Flashcards
drugs for AD
anticholinesterases:donepezil,rivastigmine,galantamine
NMDA receptor antagonist:memantine
huntington’s chorea
chlorpromazine
haloperidol
olanzepine
tetrabenazine
drugs for parkinson based on MOA
inc brain dopamine level
prevent dopamine degeneration
dopamine recptor agonists
restore DA-ACh balance
inc brain dopamine level
dopamine precursor: levodopa
decarboxylase inhibitors: carbidopa, benserazide
COMT inhibitors: tolcapone,entacapone
dopamine releasing agent: amantadine
prevent dopamine degeneration
MAO-B-INHIBITORS: selegiline,rasagiline
dopamine receptor agonists
bromocriptine,cabergoline,ropinirole,pramipexole
restore DA-ACh balance
centrally acting anticholinergic drugs: benztropine,benzhexol