Peds Flashcards
child with small or absent lymphoid tissue and recurrent sinopulmonary and gastrointestinal infections
X-linked/Bruton agammaglobulinemia (results from a failure of B cell development) Treatment=monthly IV Ig infusion
severe-combined immunodeficiency; child with severe, recurrent viral, fungal, and bacterial. infections and failure to thrive is caused by what?
adenosine deaminase deficiency=impaired T cell development
child with disseminated bacterial infections with encapsulated bacteria (strep pneumo, neisseria meningiditis)
complement deficiency
recurrent skin and pulmonary infections with catalase positive organisms (staph and serratia)
impaired oxidative burst in chronic granulomatous disease
child with hypocalcemia, cardiac defects, failure to thrive, recurrent infections
thymic hypoplasia with DiGeorge syndrome (22q11.2 microdeletion)
baby/child with hepatosplenomegaly and cherry red macula on exam
Niemann-Pick Disease
what is deficient in Niemann Pick Disease?
sphingomyelinase dificiency
cherry red macula with NO hepatosplenomegaly
Tay-Sachs Disease
what is deficient in Tay-Sachs disease?
B-hexosaminidase A deficiency
galactocerebrosidase deficiency
Krabbe disease
glucocerebrosidadse deficiency
Gaucher disease
lysosomal hydrolase deficiency with coarse facial features and corneal clouding
Hurler syndrome
what are the signs and sx in CHARGE syndrome?
- Coloboma
- Heart defects
- choanal Atresia
- Retardation of growth/development
- Genitourinary abnormalities
- Ear abnormalities
what are the signs and sx in VACTERL?
- Vertebral
- Anal atresia
- Cardiac
- TE fistula
- Renal
- Limb
jaundiced baby that starts at 3-5 days and peaks at 2 weeks; no signs inadequate breast feeding or dehydration
breast milk jaundice
jaundiced baby that runs yellow within the first week of life; has difficulty eating/latching and is dehydrated
breast feeding jaundice
treatment for breastfeeding jaundice
increase frequency and duration of feeds to stimulate milk production
growth failure and recurrent respiratory infections in infants is concerning for___
CF (pancreatic insufficiency; may also see greasy stools
what is the dosing for HPV vaccine?
- <15 years old= 2 doses 6 months apart
- >15 years old= 3 doses
most ocmmon cause of acute unilateral cervical lymphadenitis in children
staph aureus or strep pyogenes
rapidly spreading rash in children <5 years of age with fever and sloughing off of skin
staphylococcal scalded skin syndrome
rash that starts on the face and moves caudally; may have suboccipital or postauricular lymphadenopathy
rubella= German measles= togavirus
treatment of group A strep/ strep pyogenes pharyngitis?
10 days of oral amoxicillin or penicillin G
Klinefelter syndrome
47 XXY male, tall with long limbs, gynecomastia, small penis, sparse facial hair, small firm testes
lab findings characteristeic of Klinefelter syndrome
elevated FSH and TSH, low testosterone, decreased sperm count
pt with klinefelters are at increased risk of developing _____
extragonadal germ cell tumor
