Allergy and Immunology

Question 1

pt presents with fatigue, palpable purpura, arthralgias, renal disease, and peripheral neuropathies.

Answer 1

mixed cryoglubulinemia (immune complex deposition into small-medium sized vessels)

Question 2

what disease is mixed cryoglubulinemia associated with

Answer 2

Chronic hepatitis C

Question 3

lab values for positive mixed cryoglubulinemia

Answer 3

serum cryoglubulins, hypocomplementemia, positive rheumatoid factor, elevated transaminases, kidney injury