Derm

Question 1

hemidesmosomes are targeted by antibodies in which skin disorder?

Answer 1

bullous pemphigoid

Question 2

what is seen on biopsy of bullous pemphigoid?

Answer 2

• subepidermal clevage
• linear IgG deposits at the basement membrane ofn immunofluorescence

Question 3

most common sites of bullous pemphigoid?

Answer 3

flexual areas, axilla, groin

Question 4

oral lesions are common in which type of dermatologic disorder/lesion?

Answer 4

pemphigus vulgaris

Question 5

treatment for bullous phemphigoid?

Answer 5

long-term topical or systemic glucocorticoids

Question 6

biopsy shows microabsecesses at the tips of the dermal papillae. what is this?

Answer 6

dermatitis herpetiformis

Question 7

what is characteristic of on biopsy of pemphigus vulgaris?

Answer 7

acantholysis and intraepidermal cleavage

Question 8

pemphigus vulgaris involves the oral mucosa. Yes or no?

Answer 8

yes

Question 9

in pemphigus vulgaris, autoantibodies attack which protein?

Answer 9

desmosomes

Question 10

how do you treat a 3rd degree (full thickness) burn?

Answer 10

immediate excision and skin grafting

Question 11

difference between steven johnsons and toxic epidermal necrolysis

Answer 11

SJS=less than 10% body area affected

TEN=more than 30% affected

Question 12

treatment for steven johnsons and toxic epidermal necrolysis

Answer 12

supportive; IV crystalloid fluids, wound care, pain management, stop drug that caused it