Pediatrics

Question 1

Alport syndrome

Answer 1

Progressive loss of kidney function, with hearing loss, and vision changes; hematuria and proteinuria

Tx: low protein, low Na+ diet
No steroids- that’s Goodpasture’s

Question 2

Kidney casts

Answer 2

RTE casts
Tubular injury; some heptatitis, GN, nepron damage

RBC casts
Nephritic; pathognomonic of acute GN or vasculitis

Broad/waxy casts
Hallmark of nephrotic syndrome esp with mHTN, DM, RF
“Renal failure casts”

Fatty casts
Lupus, GN, lipoid necrosis

Hyaline casts
Usually normal

WBC casts
Interstitial nephritis, lupus, GN, PN