Emergency Medicine Deck 2 Flashcards
Tx for anticholinesterase or organophosphate poisoning?
atropine (supresses PNS), pralidozime (reactivates cholinesterase)
Tx for poisoning with antimuscarinic or anticholinergic agents?
physostigmine (reversible cholinesterase inhibitor)
Tx for acetominophen OD?
Tx if >7.5 ingested
give charcoal if within 4h of OD
NAC
How to treat acute heavy metal poisoning?
succimer, dimercaprol, or penicillamine
How to treat beta-blocker OD?
glucagon
How to tx barbiturate or benzo OD?
Barbituates: charcoal, dialysis, supportive care
Benzos: Flumenazil (if acute or accidental ingestion), intubation, supportive care
do not use Flumenazil in a situation of chronic benzo abuse; can cause withdrawal seizures and death
Tx for cyanide poisoning?
hydroxycobalamin, amyl nitrate, sodium nitrite
Nitrites induce methemoglobinemia, which binds cyanate
Tx for digitalis poisoning?
Anti-digitalis Fab (antibody) in patients with sx
Don’t treat ion imbalances until after initial treatment, since it will restore Na+/K+ pump
Tx for heparin or warfarin overdose?
Heparin: protamine sulfate, injected
Warfarin: FFP immediately, Vitamin K over the long-run
Tx for iron overdose?
deferoxamine
Tx for opioid overdose?
Naloxone
If patient is found unconscious and clinical suspicion suggests opioids, its standard procedure to tx empirically with naloxone
Tx for methanol or ethylene glycol (antifreeze) overdose?
Fomepizole, dialysis, Ca+ gluconate
Tx for tPA or streptokinase OD?
aminocaproic acid
Which drugs induce P-450 enzymes?
BARBara Steals Phen-phen and Refuses Greasy Carbs
Barbiturates St. John's wort Phenytoin Rifampin Griseofulvin Carbamazepine
Which drugs inhibit P-450 enzymes?
SICKFACES.COM Sodium valproate Isoniazid (Abx for TB) Cimetidine Ketoconazole (anti-fungal) Fluconazole Alcohol (chronic use) Ciprofloxacin Erythromycin Sulfonamides Chloramphenicol (synthetic strep to break clots) Omeprazole Metronidazole \++++Grapefruit