Pediatrics Flashcards
Hypertrophic cardiomyopathy
Sxs
- asx
- CP, syncope, palpitations, HF, SCD
Murmur: harsh crescendo-decrescendo systolic
- INC valsalva, squatting
- does not radiate to carotids
Dx: Echo, ECG, exercise test
Mgmt:
- avoid volume depletion
- Bblocker for children
- avoid vasodilators, diuretics, digoxin
- surgery
Avoid competitive sports
Eval q 6-12mo
Ventricular septal defect
** MC congenital heart defect
Small: asx
Large: CHF
Pulm vascular obstructive disease: pulm HTN and shunt reversal by 2nd decade of life
Acyanotic
Murmur: HOLOSYSTOLIC regurgitant LLSB murmur
Dx: echo bubble study
- Xray: increased pulmonary markings, cardiomegaly
Tx:
- spontaneous closure or surgery
Atrial septal defect
**2nd MC congenital defect
Murmur: Systolic Ejection at LUSB with Widely Split 2nd Heart Sound
Asx
- acyanotic
Dx:
- cardiomegaly
- increased pulm markings
Mgmt:
- Spontaneous closure by 1.5yo
- catheter closure
Patent ductus arteriosus
MC in preterm babies
Persistence of fetal ductus arteriosus connecting aorta to pulmonary artery
- typically closes 1-2nd day of life
Small: asx
Large: CHF
- bounding pulses = wide pulse pressure
- hyperactive precordium
Murmur: continuous machinery murmur @ ULSB or L infraclavicular area
Dx: ECG/CXR
Mgmt: Indomethacin* (premature infant)
- manage CHF w/digoxin/diuretics
- catheter closure, surgery
Coarctation of Aorta
A/w Turner syndrome and bicuspid aorta
Sxs:
- neonate w/CV collapse: ductal closure = acidosis, systemic organ failure
- infant w/CHF: dyspnea, diaphoresis, poor feeding, FTT
- child w/arterial HTN or heart murmur
- acyanotic lesion
Dx:
- difference in pulse/BP of UE vs. LE
- systolic LUSB
- CXR: inferior rib notching, figure 3 sign**
Mgmt:
- maintain ductal patency with prostaglandin* (alprostadil)
- surgical repair (<1yo)
- balloon dilation for recurrence
Tetralogy of Fallot
- MC cyanotic congenital heart disease
- VSD
- Overriding Aorta
- Pulmonary Stenosis
- RVH
- cyanosis, hypoxic spells
- tachypnea, nail clubbing
- DOE
“Tet Spell” - rapid deep breaths, irritability, crying, cyanosis, dec murmur
- mgmt: morphine, squat, correct acidosis, vasoconstrictors, propranolol
Murmur: early Systolic ejection murmur at LSB
Dx:
- Boot shaped heart* (CXR)
- Dec pulm vascular
Mgmt:
- full median sternotomy, CP bypass, R atriotomy (3-24 mo of age)
Acute Bronchiolitis
Et: RSV*
- kids <2y
Sxs:
- fever
- URI: tachypnea, retractions, expiratory wheezing*, cough, fever, otitis media
Dx:
- PE - look great but sound terrible
Mgmt:
- supportive care*: O2, fluids, nasal meds
- warm humidified high flow nasal cannula
- CPAP
- severe: racemic epi and admission
Admit: dehydration or pulse ox < 90%
Croup
Sxs
- prodrome: 1-5d of cough, coryza, fever
- 3-5d: “barking cough”** with inspiratory stridor
- worse w/crying, best w/cool air
Dx: CXR steeple sign
Mgmt:
- mild: reassurance*, humidifier, cool air
- mod/sev: nebulized racemic epi*, PO steroid w/2-4hr observation period
** MC cause of stridor
Et: parainfluenza virus
Pertussis
Et: bordetella pertussis
Sxs
- catarrhal: URI, most contagious*
- paroxysmal: staccato cough w/inspiratory whoop and post-tussive vomiting
- convalescent: dry cough
Dx: clinical
- NP swab PCR culture is gold standard
Mgmt:
- macrolide: erythromycin or azithromycin* [allergy = bactrim]
Bacterial pneumonia
Sxs:
- cough, fever (except w/chlamydia)
- tachypnea, malaise, emesis, dec BS, crackles
Dx:
- CXR not needed if well enough for OP tx
Mgmt:
- Typicals: Amoxicillin
- Atypicals: Azithromycin
Few weeks after birth: erythromycin for chlamydia
MC cause: viral
Asthma
Sxs:
- episodic wheezing, chronic, hyper responsive, reversible
- recurrent cough, tightness, dyspnea, atopy
Dx:
- check peak flow w/exacerbation
- Spirometry* = DEC FVC and FEV1/FEV ratio
- Methacholine challenge (induce exacerbation): hyperresponsive
Mgmt:
- SABA for all
- ICS maintenance
- ICS + LABA
- Leukotriene Modifier for atopic pt (montelukast)
- asthma action plan
- acute exacerbation: steroids
- uncontrolled: allergist referral
ABG with hypercapnia = worst prognosis
Cystic fibrosis
Et:
- lack/dysfunction of CFTR chloride channels = dehydrated, thick secretion
- A1at def
- auto recessive
Sxs:
- sinus: HA, mouth breathing, face pain, nasal polyp, purulent drainage
- lung: cough, sputum, pseudomonas
- pancreas: Inc fecal fat (steatorrhea), FTT
- GI: meconium ileus in neonates
- male: infertility and no vas deferens common
Dx: newborn screening
- Pilocarpine iontophoresis sweat test**
Mgmt:
- reduce pulmonary secretions to reduce bacterial bioburden
- nebulizers*
- chest physiotherapy*
- abx to cover pseudomonas w/exacerbations
- panc enzyme supplement
Hyaline membrane disease [neonatal respiratory distress syndrome]
Et:
- premature babies
- surfactant def** - inc surface tension in alveoli = collapse at end expiration
Sxs:
- tachypnea
- grunting
- retractions
- nose flare
Dx:
- CXR: fine granular parenchyma (glass)
- blood gas: hypoxia, then acidosis
Mgmt:
- prevent: Dexamethasone 48hr prior to premature delivery if before 34 weeks **
- adequate fluids, warm O2, CPAP
Most improve w/in 72hr
Foreign body aspiration
MC: food (nuts, hotdog)
Sxs:
- excessive drooling, inability to control secretion = obstruction
- hypoxia, cyanosis
Dx: Xray
Mgmt: refer for peds bronchoscopy
Acromegaly
PP: overgrowth of tissue (skin, bone, cartilage, CT)
Sxs:
- insulin resistance**
- lipogenesis
- enlarged jaw, swollen hands, feet, macroglossia, carpal tunnel, hyperhidrosis
Dx: endocrine
- serum IGF-1**
- MRI pituitary
Mgmt:
- transphenoidal surgery
- prolactinoma = cabergoline*
Gigantism
Children:
- same process as acromegaly but before growth plates close
Sxs: doughy hands
Dx:
- Inc GH
- Inc IGF-1
Dwarfism
Et:
- decreased GH secretion
- decreased IGF-1 production
- failure of tissues to respond to IGF-1
** eval if >3 SD below mean height for age
Dx:
- IGF1 (adult) and GH (child) levels
- ACTH, cortisol, TSH, FSH/LH
Mgmt: ped endocrine
T1DM
Sxs:
- polyuria, polydipsia, polyphagia
- weight loss, blurred vision, recurrent candida infection
- NV, abd pain
- acetone breath, sweet
- weakness, dizziness
Dx:
- GAD
- ICA512 - islet cell ab
- insulin antibody
- C-peptide (high w/low insulin)
Mgmt: insulin*
Conjunctivitis
Gonococcal: 3-5d purulent bilateral
- topical erythromycin ointment
Chlamydia: 5-14d scant mucoid d/c, chemosis, pseudomembrane formation
- PO erythromycin
Bacterial: HIB, strep, purulent discharge throughout day
- antibiotic drops or nothing
Viral: clear discharge
Allergic: cobblestone
Strabismus
Abnormal ocular alignment d/t EOM imbalance
Deviation of affected eye, asx corneal light reflex, head tilt or torticollis
Dx: POS cover/uncover
Mgmt:
- ophtho refer
- correct refractive error (glasses)
- surgical correction if needed
** MC cause of amblyopia
Acute otitis media
Sxs:
- sudden ear pain, fever, URI
- dec appetite, irritable, tugging ear, dec compliance
Dx:
- bulging TM
- mild bulging + recent onset of ear pain
- new onset otorrhea not d/t AOM
- middle ear effusion: need fluid in middle ear to diagnose
Mgmt:
- 6mo - 2y unilateral OR >2 = watchful waiting
- otherwise abx
Amoxicillin 80-90 mg/kg/d divided BID x 10d
Augmentin if abx in past 30d
PCN allergy: cefdinir, cefuroxime, clindamycin
Recurrent OM: ENT referral for tube placement
Chronic otitis media
TM retracted w/impaired mobility
No inflammation
Risk for hearing loss, cholesteatoma
Dx: PE
Mgmt:
- myringotomy tubes
- adenoidectomy
Cholesteatoma
Epidermal structure that replaces middle-ear mucosa and resorbs underlying bone
Sxs:
- recurrent/persistent otorrhea
- hearing loss
- tinnitus
D/t: ETC, recurrent AOM, or chronic OM
Mgmt: surgical removal
Dysfunction of eustachian tube
Tube fails to open during swallowing or yawning resulting in difference between air pressure
Sxs:
- aural fullness
- mild/mod hearing loss
- popping and cracking
- URI or allergies
Dx:
- retracted TM, dec mobility
- prominent bony landmarks
Mgmt:
- inhaled nasal steroids/decongestants [e.g. flonase + sudafed]
- antihistamines
- autoinflation (e.g. gum chewing)
Mastoiditis
Extension of middle ear infection through mastoid air cells
- ant/inf displacement of pinna
- erythema of pinna and mastoid
- mastoid tenderness
- otorrhea, fever
Dx: CT
Mgmt:
- admit!
- broad spec IV abx
- may need surgical debridement
Otitis externa
Inflammation of skin in external ear canal
Ear pain w/pressure to tragus or tugging
Erythema, edema, otorrhea, foul smell
Mgmt: topical steroid, antimicrobial +/- wick
- Ciprodex
- Ofloxacin
Need to make sure TM not perforated before giving steroid drop**
Tympanic membrane perforation
D/t trauma or infection
Dx: PE
- audiologic evaluation
Mgmt:
- dry ear precautions*
- trauma: resolves itself
- infection: abx oral and drops, recheck
Refer for persistent hearing loss
Acute pharyngitis
Sxs:
- fever, HA
- beefy red tonsils
- petechiae
- anterior cervical LAD
- abd pain
Dx: rapid strep w/culture reflex
Mgmt:
- PCN/amoxicillin if GAS+
- allergy: azithromycin
Epiglottis
Sxs:
- preceding URI, abrupt onset, sore throat, odynophagia, resp distress
- drooling, choking sensation, hot potato voice, sniffing position
Dx: laryngoscopy*
- Neck Xray: thumbprint sign
Mgmt:
- secure airway
- abx therapy, blood culture and epiglottic swab before
Oral candidiasis
Creamy white plaques on tongue and buccal mucosa
- usually throughout mouth, not just tongue
Scrapes off
- can bleed
peaks at 4wk
Dx: clinical
Mgmt:
- Nystatin swish 2mL TID or diflucan
GERD
Infant:
- effortless postprandial regurgitation
- irritable during feedings
- FTT
Child:
- recurrent vomiting
- chest/abd pain
Dx:
- pH monitor
- PPI therapy
- serial EGD to r/o mucosal changes
Mgmt:
- reduce acidic foods, caffiene
- weight loss, upright sleep, stress reduce
- reassurance, small frequent feeding
Treat when FTT begins:
- H2ra approved for <1yo
- Kids: omeprazole
Nissen fundoplication
- failed med therapy
- respiratory sxs
- vocal cord damage
- Barrett’s
Pyloric stenosis
Sxs:
- projectile vomiting, non-bilious
- palpable olive
Dx: U/S - pyloric wall greater than 4mm wide or 14mm long
Barium swallow: string sign
Mgmt:
- surgical consult
- ER management
Labs**
- hypochloremic
- hypokalemic
- metabolic alkalosis
Celiac disease
Systemic autoimmune disease triggered by gluten (BROW)
- villous atrophy, crypt hypertrophy, malabsorption
Sxs:
- diarrhea, bloating, abd pain, anemia, wt loss, fatigue, vitamin deficiency
- pruritic vesicular rash
Dx:
- Iga-TTG
- anti-endomysial abs
- dermatitis herpetiformis* skin bx
- gold standard: small bowel histology from bx
Mgmt: lifelong gluten free
- supplement Vit d, Ca, Fe
- eat CRAP: corn flour, rice flour, arrowroot, potatoes
Constipation
Large stool can result from colon stretching and not defecating enough
Sxs:
- firm stool, abd pain
- diarrhea, urinary sxs
- fatigue
Mgmt:
- infant: 1-2oz fruit juice, glycerin suppositories
- child: avoid pasta, fried food, and dairy – more fruit, veg, water, activity + positive reinforcement
- PEG x 6-12 mo
Fe in formula and breast milk does not cause constipation
Intussusception
- vomiting + colicky abdominal pain + currant jelly stool **
- other sxs: mass, occult blood, lethargic, septic
MC < 5yo
Cause:
- palpable purpura (a/w HSP)
- tumor
- Meckel’s diverticulum
Dx: U/S target sign
- barium/air enema
Mgmt
- barium/air contrast enema (r/o perforation)
- surgery if peritonitis present
Lactose Intolerance
Bloating, flatulence, diarrhea, cramps a/w lactose intake
Dx: Hydrogen breath test
- clinical dx
Mgmt:
- reduce/eliminate dairy
- lactaid supplement
- calcium supplement
Fecal impaction
Atypical presentation of constipation confirmed by DRE
RF: opioid, bed rest, neurogenic or spinal disorder
Sxs:
- NV, abd pain, anorexia, distension, diarrhea
Mgmt:
- digital disimpaction
- suppositories, enemas
PKU (Phenylketonuria)
Autosomal recessive
Sxs:
- intellectual disability and seizures w/out any treatment
- fair skin, light hair, musty odor, microcephaly, hyperactivity
Mgmt:
- low phenylalanine diet
What do you measure for general nutrition status?
Prealbumin
Vitamins
A: night blindness, Bitot spots
C: scurvy - ecchymosis, malaise, arthralgias
D: osteomalacia, Rickets
E: ataxia, hyporeflexia
K: bruising, GI/mucosal bleeding
Folate: anemia, neural tube defects
Thiamine (B1): Wernicke encephalopathy, Beriberi or peripheral nephropathy
Niacin (B3): pellagra - dermatitis, diarrhea, dementia
Cobalamin (B12): anemia, paresthesias, ataxia, depression
Iron def is common in ages 1-3y if not supplemented during breastfeeding