Pead 5 Flashcards
Neonatal herpes symptoms pathogenesis?
Intrautine(rare but fatal)
Intrapartum(coomon in active viganal infection)
postpartum(if there active sore)
CM?
Mucocutaneous vesicle and keratoconjunctivitis
CNS form:Seizure, fever, and lethargy
Dissiminated:Sepsis, hepatitis, and pneumonia
Imaging?
Temporal heamorage and edema
Managment?
Acyclovir
Transient synovitis pathogenesis?
Inflamation of tissue surounding Hip joint
CM?
3-8 year No fever joint pain Limping Decrease hip joint movt Keep hip in flexed and external rotation in supine(wide joit space) Resist I.rotation and extension Resolves whithin 1-4 week Able to bear wight
Diagnosis?
Near normal CBC.eSR and CRP
U/S of hip:Unilateral/bilateral hip effiution
Managment?
Suportive
NSAID
Primary humoral deficiency CXS?
Recurent and sever sinopulmonary infection by virus and encapsulated organ.
What are the causes?
BA H IgM S. CVID Ig A deficiency Selective Ig g deficiency
How to D/T?
BA–Low B-cell
Other–Normal B cell
What to do next?
Classify based on Ig level
When will be Thyroglosal Cyst diagnosed?
When infected after RTI
Having immaginary friend is normal in which age?
3-6
Effect on child?
Benificial(improve creativity and rehersal for good social intraction)
Other normal bizzare behaviour in thise age?
Dressed -UP
Pretend play
Story telling with fanciful details
Facial menifestation of anaphlaxis?
Conjectival redness and B.pain and periorbital edema
Tongu and lip swelling
Alport syndrome genetics?
X-linked recesive
Due to type IV collagen defect
CM?
Renal:Asymptomatic Heamaturia and Progresive RI ----+/- rotinuria and HTN SN hearing loss Anterior lenticonus(lence protrusion) Groos heamaturia after RTI
Diagnosis?
Molocular
Longtiudnal GBM spliting
Norml complement
Neonatal sepsis sign?
Sepsis sign
lethargy
Poor feeding
Jaundice(sepsis imair conj.)
Investigasion?
CBC
LP
Blood culture
Urinalysis
Why we do LP w/o head CT in neonate?
Because of open fontanel they have no herination risk
What sighn help to D/T Hemocystinuria from MS?
Hemocystinuria is Autosomal recessive Due to cystionin syntase deficiency Intelectual disablity Thrombosis risk Downward lence orientation Fair cmplexion(blu sclera and skine) Megaloblatic anemia
Managment?
B-6 Folic acide B-12 Cystionin Antiplatelet/Anticoagulant
what about ehler dhalol?
No disproporsionate bodie
No lense dislocation
Aplastic anemia pathophysiology?
MCC aplastic anemia
Bone marow failure
Due to DNA repair deffect
CM?
Sort stature Hypoplastic tumb/thenar athrophy Polyductyly Hyper/Hypoppigmentation Genitourinary malformation
LAB?
Pancytopnia Megaloblastic anemia(erythropoisis) posetive chromosoal breakage
Managment
Steem cell translantation
Fungal ottitis externa Cxs?
Occur after bacterial OE
Insidious onset
Aspargilus and candidia
White friable derbis
Croup pathophysiology?
Due to Parainfluena infection of larhnex and thrachia
Larengio-bronchitis
Subglotic sweeling(x-ray)
CM?
Inspiratory stridor
Hoarsenesness
Barking cogh
Managment?
o2 if Spo2 <92
Mild(no stridor at rest): Cs + humid air
Sever(stridor at rest):Cs + nabulizer ephiniphrine
MV if have sighn or RF
Sever combine ID sighn?
Recurent/Sever viral/bcterial ,oportunstic and fungal infection
Chronic diarrhea
Growth restriction
Pathophysiology?
Absent CD3(T cell)(developmental defect) B-cell dysfunction due to absent T cel
Managment?
T-Cell steem cell transplantation
Drug should be avoided in G6PDH deficiency?
Dapsone Isobutyl nitrate Nitrofurantoin Primaquine Rasburicase
Cause of congenital lymphedema?
Lymphatic chaneel defect due to lymphatic NTW dysgenesis.
Vit A importance in Measel?
Decrease morbidity and mortality
By improving Ab formation and reepithelization
Measel complication?
encephalitis
Pnumonia
Blindness
In who to give?
extreme age(old and children) Imunocompromized Vit A deficeint Pregnant Require hositalization
CM?
Predorm(cogh,coryza,koplic spot,fever,conj.)
Rash(cephalocaudal,centrifugal)
How pertusis cause facial petiche and subconjectival heamorage?
Because of high intrathoracic P–capillary injury
mamography is not good at?
If age <30–large breast tishu make difficult for assesment
Fibroadinoma cxs?
Common in upper outer quadrant
Perimenestrawal mass tenderness
generaly breast ca rare in adolecent and chikdren?
Yes
cause NRDS?
Prematurity
DM
c/S
Perinatal asphexia
Diagnosis of cartenger?
intranasal NO
Common cause of atroke in children?
SCD Protrombic disorder CHD Bacterial meningitis Vasculitis Foccal cerebra; artheriohaty Head/Neck trauma
