PCTH - Opioid/Hypoglycemia/Adrenal Crisis Directives Flashcards

1
Q

What is glucagon?

A
  • hormone produced by alpha cells in the pancreas that is naturally released when blood glucose levels drop
  • causes liver to convert glycogen stores into glucose
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2
Q

Does glucagon always work? Why or why not?

A

may not always work because if you have already used up your glycogen stores, then glucagon will not work (no more stores to access)

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3
Q

Glucagon is classified as a _________ agent. Besides acting on liver glycogen, what other effects does it have?

A

hyperglycemic agent

relaxes smooth muscles of the stomach, duodenum, small bowel, and colon (so somettimes IV glucagon is given at the hospital to relax smooth muscles for relieving esophageal foreign bodies)

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4
Q

The treatment of choice for hypoglycemia in the pre-hospital setting is

A

dextrose

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5
Q

What form does dextrose come in and how is it administered?

A
  • D50 or D10 (50% or 10% dextrose in water)
  • 50G/100mls
  • considered a caloric agent
  • administsered IV only (cannot be injection because will cause almost instaneously necrosis)
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6
Q

Hypoglycemia Medical Directive

Indications

Conditions

Contraindications

A

Indications: suspected hypoglycemia

Conditions:

  • Dextrose: ≥2 y.o., altered LOA, hypoglycemia
  • Glucagon: altered LOA, hypoglycemia

Contraindications:

  • Dextrose: allergy or sensitivity to dextrose
  • Glucagon: allergy or sensitivity to glucagon; pheochromocytoma (rare adrenal tumor that can cause massive release of epinephrine increasing risk of stroke if given glucagon)
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7
Q

Hypoglycemia Medical Directive

Treatment

Clinical Considerations

A

Treatment: see screenshot

  1. Consider glucometry
  2. Consider dextrose (if available and authorized)
  3. Consider glucagon (if not using dextrose)

Clinical Considerations:

  • If pt responds to dextrose or glucagon, they may receive oral glucose or other simple carbs
  • If only mild S/S exhibited, pt may receive oral glucose or other simple carbs instead of dextrose or glucagon
  • If a patient initiates an informed refusal of transport, a final set of vital signs including blood glucoemtry must be attempted and documented
  • IV admin for PCP Autonomous IV only
  • note (this one not in ALS): all pts who take oral hypoglycemic agents (metformin, glyburide, glicazide) should be transported to hospital after hypoglycemic event (due to long half time of the drug so will continuously work in system and cause hypoglycemic event to bounce back)
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8
Q

Hypoglycemia Medical Directive
Considerations for Treat & Discharge (if authorized)

A

Pt must meet all the following criteria:
* ≥18 AND <65 years old;
* has Dx of diabetes
* hypoglycemia can be explained by insulin administration w/ inadequate oral intake
* hypoglycemia responded to single admin of dextrose and/or 1mg glucagon and/or consumed oral glucose or other complex carbohydrates
* this is single isolated episode of symptomatic hypoglycemia within the past 24 hours
* BGL >4mmL after tx
* pt returned to normal LOC & asymptomatic
* a complete set of vital signs are within expected normal ranges

AND
* not an intentional OD
* hypoglycemia must not be related to alcohol or substance abuse or withdrawal
* no seizure/reported hx of seizure prior to paramedic tx
* not on an oral hypoglycemic medication
* hypoglycemia is not considered to be related to an acute medical illness
* pt not pregnant

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9
Q

If pt meets criteria for treat & discharge following hypoglycemic events, what should the paramedic do?

A
  1. pt has access to appropriate carbs
  2. responsible adult agrees to remain with pt for the 4 hrs
  3. all of pt or SDM questions answered & care plan developed
  4. pt/SDM has been advised to follow up with 1’ health care team/provider
  5. clear instructions to call 911 were provided should sx redevelop
  6. pt/SDM has ability to access 911 (if ^)
  7. pt/SDM consents to discharge

PATCH to BHP for consult if you are unclear if pt meets all of the discharge criteria

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10
Q

What S/S would cause you suspect hypoglycemia?

A

agitation

altered LOA/LOC (or syncope)

seizure

CVA Symptoms

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11
Q

Describe the steps you would take to a BGL.

A

1) Prep site: use alcohol swab on side of finger and ensure swab comes back clean (or else continue wiping until it’s clean) & allow dry (alcohol can inaccurately skew the BGL reading)

2) Obtain sample: need ARTERIAL drop of blood

3) Treat site

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12
Q

What BGL is considered hypoglycemia?

A

if ≥2 yo: < 4.0 mmol

if <2 yo: <3.0 mmol

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13
Q

To determine if patient needes a second dose, aftering the appropriate dosing interval what do you have to do?

A

ensure they are still meeting clinical parameters (i.e. take a BGL, assess LOA, etc.)

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14
Q

If a patient gives themself glucagon/dextrose prior to EMS arrival, are you still allowed to give the amount of drug allocated within your medical directive?

A

Yes - you can ALWAYS max out your drug directives (the only exception is if the doses given to the patient is by another on-duty paramedic such as a first response truck)

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15
Q

Describe the steps for administering injections.

A

1) Prepare site: EtOH swab (if it’s <1mL of solution, you can use deltoid, if >1mL the use bigger muscle mass)

2) Check the drug - can also double check with partner

3) Prepare the drug - prepare syringe and materials, and first aid stuff if you need to treat site after; DO NOT SHAKE GLUCAGON (or else lots of bubbles will form and you will have to wait or throw it out)

4) Administer the drug - spread the skin so it’s tight, aspirate to ensure no blood, and then complete a slow steady injection

5) Follow up care

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16
Q

When would it be appropriate to provide the patient with oral glucose?

A
  • Administer once patient’s LOA increases
  • can be administered if patient is exhibiting mild S/S
  • 15-30g each tube (and you want pt to have 30 g total)
  • taken sublingually
  • Explain to patient: even though they are feeling better, this will help build up those glycogen stores so it’s good
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17
Q

What are the 6 rights to drug administration?

A

1) Right patient - they meet all the conditions, indications, contraindications, etc.

2) Right drug

3) Right time

4) Right dose

5) Right route

6) Right to Know - why we are giving it, what benefits it may have

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18
Q

Opiate vs opioid

A

Opiate: narcotic drug from a natural source

Opioid: narcotic drugs that bind to opioid receptors including synthetic compound (anything that is manufactured)

19
Q

Common Opioids (13)

A
  • Heroin (smack, H, horse)
  • Morphine (statex, MS Contin)
  • oxycodone (Oxycontin, Oxyneo)
  • Percocet (oxycodone, acetaminophen)
  • Percodan (Oxycodone + ASA)
  • hydromorphone (Dilaudid)
  • pentazocine (Talwin)
  • fentanyl (Duragesic)
  • codeine (Tylenol 2, 3)
  • methadone
  • Suboxone (buprenorphine + naloxone)
  • Demerol (meperidine)
  • opium
20
Q

Common street names for Bath salts

A

Meow meow

Drone

Lunar X

21
Q

Common street names for cocaine

A

yayo

sneeze

Bernice

22
Q

Common street names for fentanyl

A

Apache

Dance Fever

Goodfella

23
Q

Common street names for crystal meth

A

Tina

Go

Whizz

24
Q

Common street names for heroin

A

Dragon

Skunk

Boy

25
Q

Common street names for Ketamine

A

Honey Oil

Special La Coke

Purple

26
Q

Common street names for Oxycontin

A

Kickers

Hillbilly Heroin

27
Q

Routes of entry for opioid overdose

A
  • injection
  • PO
  • Absorption (transdermal) - like fentanyl patches
  • Intranasal (snorting)
  • Inhalation (smoking)
28
Q

Short acting opioids

A
  • morphine
  • fentanyl (PO/IV)
  • hydromorphone
  • Heroin
29
Q

Long acting opioids

A
  • methadone
  • Oxycontin
  • Transdermal Fentanyl
30
Q

What are the 3 types of opioid receptors in the body?

A

mu

kappa

delta

31
Q

Key features of an opioid OD

A
  • altered mental status - confusion, agitation, delirium, unconsciousness
  • hypoventilation
  • bradycardia
  • hypotension
  • pulmonary edema
  • hypothermia
32
Q

Opioid Overdose Triad

A

1) Decreased LOA

2) Miosis (pinpoint pupils) - however cannot always rely on this because if they are mixing with other drugs like cocaine, they may not always show this)

3) Respiratory depression

33
Q

What is naloxone?

A
  • aka Narcan
  • Strong opioid antagonist
  • competes with opiates to bind with receptors in the CNS
  • if no opioids are there, naloxone just won’t do anything and you’d just wait for it to pass our of your system
34
Q

Naloxone is supplied most commonly in what dosages?

A

0.4 mg/ml

2 mg/ml

35
Q

Onset of naloxone via IM/SC, IN, and IV

A
  • IM/SC: 2-5 minutes
  • IN: 8-18 minutes
  • IV: 1-2 minutes
36
Q

Duration of naloxone (i.e. half life)?

A

30-60 minutes

37
Q

During an opioid overdose when naloxone is given, what can it potentially cause/lead to?

A
  • agitation
  • withdrawal symptoms
  • unmask a toxidrome
  • response to naloxone is unpredictable
38
Q

Opioid Toxicity Medical Directive

Indications

Conditions

Contraindications

A

Indications:

  • Altered LOC AND
  • Resp depression AND
  • Inability to adequately ventilate OR persistent need to assist ventilations; AND
  • suspected opioid overdose

Conditions: for Naloxone

  • Age: ≥24 hours
  • LOA: altered
  • RR: <10 breaths/min

Contraindications: allergy or sensitivity to naloxone

39
Q

Opioid Toxicity Medical Directive

Treatment

Clinical Considerations

A

Treatment:

  • IV: Titrate naloxone only to restore patient’s respiratory status.
    • Dose: up to 0.4mg (only enough to restore resp status)
    • Max single dose: 0.4mg
    • Dosing interval: 5 mins (timer starts when you finish completing the dose)
    • Max # of doses: 3
  • IM: can give via deltoid
    • Dose: 0.4mg
    • Max single dose: 0.4mg
    • Dosing interval: 5 mins
    • Max # of doses: 3
  • IN:
    • Dose: 2-4 mg
    • Max single dose: 2-4 mg
    • Dosing interval: 5 mins
    • Max # of doses: 3
  • SC: can give in deltoid
    • Dose: 0.8mg
    • Max single dose: 0.8mg
    • Dosing interval: 5 mins
    • Max # of doses: 3
  • Note: Take police and fire with you!

Clinical Considerations:

  • IV administration applies only to PCPs authorized for PCP Autonomous IV
  • Upfront aggressive management of the airway is paramount and the initial priority.
    • i.e. if you can control the airway and get to the hospital in a reasonable time then you don’t have to give it
  • If no response to initial treatment; consider patching for further doses.
  • If the patient does not respond to airway management and the administration of naloxone, glucometry should be considered.
  • Combative behaviour should be anticipated following naloxone administration and paramedics should protect themselves accordingly, thus the importance of gradual titrating (if given IV) to desired clinical effect: respiratory rate ≥10, adequate airway and ventilation, not full alertness.
40
Q

What is the primary goal of Naloxone?

A

restoration of adequate spontaneous respirations NOT wakefulness (which is why we don’t give it to VSA pts)

41
Q

Common stressors that may cause a “stable” patient with primary adrenal failure (Addison’s disease) to present in crisis

A

hypoglycemia
infection/illness
trauma/surgery

note that hydrocortisone is lifesaving in these situations so if pt is hypoglycemic & experiencing adrenal crisis, give hydrocortisone first

42
Q

Suspected Adrenal Crisis Medical Directive

Indications

Conditions

Contraindications

A

Indications: A pt with primary adrenal failure who is experiencing clinical signs of an adrenal crisis

Conditions: Hydrocortisone

  • Other:
    • Paramedics presented with vial of hydrocortisone for pt AND
    • Age-related hypoglycemia OR
    • GI sx (vomiting, diarrhea, abdo pain) OR
    • Syncope OR
    • Temp ≥ 38C or suspected/hx of fever OR
    • Altered LOA OR
    • Age-related tachycardia OR
    • age-related hypotension

Contraindications: allergy/sensitivty to hydrocortisone

43
Q

Suspected Adrenal Crisis Medical Directive

Treatment

Clinical Considerations

A

Treatment:

  • Route: IM/IV
  • Dose: 2mg/kg* (rounded to the nearest 10mg)
  • Max single dose: 100mg
  • Dosing interval: n/a
  • Max # of doses: 1

Clinical Considerations: IV admin of hydrocortisone for PCP AIV only.

44
Q

If giving IM hydrocortisone, where is the optimal location for injection?

A

vastus lateralis (quick uptake of medication since these pts are very sick)