PCOS and Rh antibodies Flashcards

1
Q

The key pathogenesis of PCOS is increased secretion of ___ by the anterior pit.

A

LH

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2
Q

In PCOS there is a LH/FSH ratio that is greater than _:1

A

3:1

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3
Q

The symptoms of PCOS can begin around the age of ________

A

menarche (avg. 12.8)

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4
Q

PCOS causes increased insulin levels and insulin (hypersensitivity/resistance)

A

resistance

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5
Q

PCOS is associated with weight (loss/gain)

A

weight gain

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6
Q

PCOS leads to an increase the male hormone ________

A

testosterone and androstenedione

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7
Q

In polycystic ovarian syndrome the follicles that that are not the main follicle turn into ______

A

cysts!

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8
Q

In PCOS the serum SHBG is (increased/decreased)

A

decreased

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9
Q

PCOS is characterized by (polymenorrhea/ oligomenorrhea)

A

oligomenorrhea

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10
Q

What could you recommend to an obese woman with PCOS?

A

weight loss improves symptoms

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11
Q

How do oral contraceptives effect PCOS?

A

induce regular menses, inhibit ovarian androgen production, increase SHBG

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12
Q

In the Rh blood group systen we generally discuss just the ____ antigen to determine the risk of hemolytic disease of the newborn

A

D

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13
Q

In the Rh blood system there are over 50 defined factors by the 5 most important are

A

D, C, c, E, and e

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14
Q

SHBG has a preference for binding (Testosterone/estrogen)

A

testosterone

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15
Q

Decreased SHBG such as in PCOS leads to more free (Testosterone/estrogen)

A

testosterone

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16
Q

Estrogen (promotes/inhibits) SHBG

A

promotes synthesis of SHBG

17
Q

Accumulation of fluid in a follicle or in a previously rupture follicle is called a ______ _______

A

follicular cyst

18
Q

a condition in the fetus characterized by an accumulation of fluid, or edema, in at least two fetal compartments

A

Hydrops fetalis

19
Q

When LH hits the theca cell, it produces _______. When FSH hits the granulosa cell _________

A

LH-> androgens

FSH->androgens are converted to estrogens