pathway regulators Flashcards
1
Q
describe how increased insulin impacts the pathways
A
increases glycolysis
2
Q
describe how increased glucagon impacts the pathways
A
increases gluconeogenesis
3
Q
describe how increased ATP impacts the pathways
A
decreases glycolysis and TCA cycle, increases gluconeogenesis
4
Q
describe how increased cortisol impacts the pathways
A
decreases glycolysis and TCA cycle, increases gluconeogenesis
5
Q
describe how increased fructose-2,6-bisphosphate impacts the pathways
A
- increases PFK, which stimulates glycolysis
- decreases fructose-1,6-bisphosphatase, which inhibits gluconeogenesis
6
Q
what inhibits liver PFK1
A
citrate
7
Q
what inhibits non-liver PFK1
A
lactate and H+
8
Q
what is the rate limiting enzyme of glycolysis
A
PFK
