Pathophys of Acute Liver Failre

Question 1

What is the most common causeof acute liver failure

Answer 1

viral

Question 2

when are you most worried about liver failure with hev?

Answer 2

pregnant women

Question 3

what are various hepatotoxic drugs?

Answer 3

anesthetics - halothane
non-steroidals
anti-tb (isoniazid)
acetominophen
mushroom poisoning
herbal remedies
alcohol

Question 4

what are vascular causes of acute liver failure?

Answer 4

budd-chiari
hypotension
hypoxia

Question 5

what are various metabolic liver failure causes?

Answer 5

wilson’s dz
fatty liver of pregnancy
reye’s syndrome

Question 6

what is characteristic of wilson’s dz?

Answer 6

ceruloplasmin low, copper high, psychiatric problems, hemolysis with hepatic failure
high school,

Question 7

what is reye’s syndrome?

Answer 7

givin aspirin to kids with fevers

Question 8

eosinophils with liver dz associated with

Answer 8

parasites, rx-induced

Question 9

neutrophils with liver dz associated with

Answer 9

alcohol-induced

Question 10

in acute liver failure, do we commonly see hypoglycemia, increased insulin, lactic acidosis

Answer 10

yes

Question 11

What does hyponatremia refect in live dz?

Answer 11

cell death, total body Na high but not intravascular

Question 12

When do you get ATN

Answer 12

uNA>20

Question 13

wht factors for coagulopathy does the liver produce

Answer 13

everything except 8 and inhibitors, platelet production and function abnormal

Question 14

what are bad indicators for survival of acute live dz

Answer 14

under ten and over forty
small liver
ascites
jaundice less than 7 days before enceph
hypoglycemia
hapticyte necrosis over 75%