Pathology of Large bowel- Non neoplastic Flashcards
Diverticular disease is often asymptomatic. T/F?
True
What are the complications of Diverticular disease?
- Inflammation 2. Rupture 3. Abscess 4. Fistula 5. Massive bleeding
What two histological changes are seen in Ischaemic disease of the large bowel?
- Whithering of crypts
- Smudging of lamina propria
Ischemic bowel disease is more common in the elderly. T/F?
Tru
Ischaemia commonly affects the right side more. T/F?
False- left side
What factors contribute to the atieology of Ischaemia of the large bowel?
- Atherosclerosis of mesenteric vessels
- AF
- Embolus
- Shock
- Vasculitis
What are the complications of ischaemic colitits?
- Massive bleeding
- Stricture
- Rupture
What are the histological changes in antibiotic induced or Psuedomembranous colitis?
1, Patchy yello membranous exudate on mucosal surface
- Explosive lesions on mucosa
V commonly casued by C. difficile -Treat with Flagyl/Vancomycin
Presenting complaints of pseudomembranuos colitis?
Massive diarrhoea and bleeding
What is the histological change in collagenous colitis?
Increase in thickness of sub-epithelial collagen
Main symptom of collagenous colitis?
Watery diarrhoea
There are no chronic architectural changes in Collagenous colitis. T/F?
True
Classic histological change in Lymphocitic colitis?
Massive increase in intra-epithelial lymphocytes- again no chronic structural changes, no BM thickening
Main symptom of lyphocytic colitis?
Watery diarrhoea
Needs an endoscopy to daignose, correct history also important.
Coeliac disease can be a possibility.
Microscopic colitis can either be _ colitis or _ colitis in nature.
Lymphocitic or Collagenous
