Irritable Bowel Syndrome Flashcards
What are the worrying signs of IBS
- In wheelchair due to pain - Given up work due to pain - Needs to carry water all the time to cope
Is IBS a chronic or acute disease?
Chronic
Three main symptoms of IBS?
- Abdominal pain
- Abdominal bloating
- Atlered bowel habbit- causing constipation or diarrhoea
Genetic and environmental factors play a role in IBS. T/F?
True
What is visceral hypersensitivity?
Sensory nerve endings in the intestinal wall have an abnormally strong response to stimuli, especially during or after a meal.
Everything from digestion to urination becomes very painful
What is the Rome III criteria?
- Recurrent abdo pain/discomfort at least 3 days per month for 3 months + 2 or more of- -
Improvement with defecation -
Onset assoc with stool frequency - Onset assoc with stool form
Some other symptoms of IBS?
- Bloating - Urgency - Sensation of incomplete emptying - Mucus per rectum - Nocturia - Stress aggrevation
IBS can be related to what other illnesses? (hint- pain + tired)
- Fibromyalgia
- Chronic fatigue syndrome
- TMJ dysfunction
- Chronic pelvic pain
IBS is closely related to what psychological disorder?
Anxiety/depression- seen in 50% of cases
Important aspects of history in IBS
- Bowel habit- bloating, nocturia
- Diet: bread, fibre, meal times
- Trigger factors: infection, menstruation, drugs
- Opiate use: codeine & opiate bowel syndrome
- Stress
What are the Alarm features that the problem is not IBS but something else?
- Age > 50yrs
- Short duration of symptoms
- Woken from sleep by bowel habit
- Rectal bleeding
- Weight loss
- Anaemia
- Family history
What investigations are needed for IBS?
- FBC
- ESR/plasma viscocity
- CRP
- Antibody testing for Coeliac
- Lower GI tests if aged >50 or strong FH of colorectal cancer
What are the two main mainstay’s of treatment?
- Diet- reduce fibre FODMAP/GFD
- Drugs- Stop Opiates, Anti diorrhetics, anti-spasmodics, anti- depressants
What are the first line treatments for IBS relating to the following symptoms:
- Pain
- Constipation
- Diarrhoea
- Pain- Antispasmodics eg Alverine, Mebeverine
- Constipation- Laxatives avoid lactulose eg Bisacodyl
- Diarrhoea- Loperamide anti diarrhoeal.
2nd line treatment in IBS? (Hint- depres)
Anti-depressants
Tricyclics- eg Amitriptyline: 20mg
Reduce diarrhoea by reducing afferent signals from the gut.