IBD: Therapy

Question 1

What lifestyle advice would you give to IBD patients?

Answer 1

Smoking aggrevates Crohn’s- reduce/stop it

Diet not involved in pathogenesis but can influence symptoms

Question 2

What are the therapy options for UC?

Answer 2

1. •5ASA (mesalazine)
2. •Steroids
3. •Immunosuppressants
4. •Anti-TNF therapy

Question 3

Therapy options for Crohn’s?

Answer 3

1. Steroids
2. Immunosuppressants
3. Anti-TNF therapy

Question 4

What are the drug effects of 5ASA? What are some side effects?

Answer 4

Topical- Anti-inflammatory properties. Reduces risk of colon cancer.

Side effect- Diarrhoea, Nephritis

Question 5

5-ASA can be delivered orally or topically.