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First Aid Reproductive Chapter > Pathology - Malignant Ovarian Neoplasms > Flashcards

Pathology - Malignant Ovarian Neoplasms Flashcards

1
Q

Most common malignant stromal tumor of the ovaries

A

Granulosa Cell Tumor

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2
Q

Who gets Granulosa Cell Tumors?

A

Predominantly women in their 50s.

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3
Q

What is secreted by Granulosa Cell Tumors?

A

Often produces estrogen and/or progesterone

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4
Q

How does a Granulosa Cell Tumor present? (3)

A

presents with postmenopausal bleeding, sexual precocity

(in pre-adolescents), breast tenderness.

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5
Q

What ovarian neoplasm has Call-Exner bodies?

A

Granulosa Cell Tumor

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6
Q

What is a Call-Exner Body?

A

granulosa cells arranged haphazardly around collections of eosinophilic fluid, resembling primordial follicles

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7
Q

Most common malignant ovarian neoplasm?

A

Serous Cystadenocarcinoma

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8
Q

What ovarian malignant neoplasm is frequently bilateral and has Psammoma bodies?

A

Serous Cystadenocarcinoma

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9
Q

What ovarian tumor is a Pseudomyxoma peritonei–intraperitoneal accumulation of mucinous material from ovarian or appendiceal tumor.

A

Mucinous cystadenocarcinoma

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10
Q

What ovarian tumor is Aggressive, contains fetal tissue, neuroectoderm.

A

Immature Teratoma

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11
Q

When is an immature teratoma diagnosed?

A

Commonly diagnosed after menopause.

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12
Q

What malignant ovarian neoplasm is most commonly found in adolescents?

A

Dysgerminoma

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13
Q

Dysgerminoma is equivalent to what in males?

A

Seminoma, but rarer

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14
Q

What ovarian cancer has Sheets of uniform “fried egg” cells?

A

Dysgerminoma

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15
Q

Tumor markers for Dysgerminoma?

A

hCG, LDH

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16
Q

Most common tumor in male infants?

A

Yolk Sac (Endodermal Sinus) Tumor

17
Q

Where are Yolk Sac tumors found?

A

ovaries or testes (boys) and sacrococcygeal area in young children.

18
Q

What ovarian tumor is a Yellow, friable (hemorrhagic), solid mass?

A

Yolk Sac (Endodermal Sinus) Tumor

19
Q

What tumor has Schiller-Duval bodies (resemble glomeruli)

A

Yolk Sac (Endodermal Sinus) Tumor

20
Q

What is the tumor marker for Yolk Sac Tumors?

A

AFP

21
Q

What is a Krukenberg tumor?

A

GI malignancy that metastasizes to ovaries

22
Q

What do you see on histo?

A

mucin-secreting signet cell adenocarcinoma.

First Aid Reproductive Chapter (13 decks)

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