Pathology - Benign Breast Flashcards
Who gets Fibroadenomas?
Most common in women under 35 years.
Describe a fibroadenoma. Does it change with estrogen?
Small, well-defined, mobile mass.
size and tenderness with estrogen (eg, pregnancy, prior to menstruation).
Is there increased risk for cancer with fibroadenoma?
Risk of cancer is usually not increased.
Who gets Fibrocystic Changes?
Most common in premenopausal women > 35 years
How do fibrocystic changes present?
Presents with premenstrual breast pain or lumps; often bilateral and multifocal.
What is described as Nonproliferative lesions include simple cysts (fluid- lled duct dilation, blue dome), papillary apocrine change/metaplasia, stromal fibrosis.
Fibrocystic Change of the breast
Is there increased risk for cancer with Fibrocystic Changes?
Risk of cancer is usually not increased.
What is described as increased acini and stromal fibrosis, associated with calcifications.
Sclerosing Adenosis
Is there increased risk for cancer with Sclerosing Adenosis?
2x increased risk for cancer.
what is described as small papillary tumor within lactiferous ducts, typically beneath areola.
Intraductal papilloma
Most common cause of nipple discharge (serous or bloody)?
Intraductal papilloma
Is there increased risk for cancer with Intraductal Papilloma?
2x risk for cancer.
What is Epithelial Hyperplasia of the breast?
increased cells in terminal ductal or lobular epithelium
Is there increased risk for cancer with intraductal Papilloma?
increased risk of carcinoma with atypical cells.
What is a Phyllodes Tumor?
Large mass of connective tissue and cysts
