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First Aid Reproductive Chapter > Pathology - Benign Ovarian Neoplasms > Flashcards

Pathology - Benign Ovarian Neoplasms Flashcards

1
Q

Most common adnexal mass in women > 55 years old?

A

Ovarian Neoplasm

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2
Q

Majority of malignant tumors are derived from what?

A

epithelial in origin

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3
Q

Risk for Ovarian Cancer increases with what? (4)

A

advanced age, infertility, endometriosis, PCOS

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4
Q

What three genetic predispositions lead to Ovarian Cancer?

A

BRCA-1 or BRCA-2 mutation
Lynch syndrome
strong family history

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5
Q

what decreases risk of ovarian cancer? (4)

A

previous pregnancy, history of breastfeeding, OCPs, tubal ligation

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6
Q

Ovarian cancer presents how?

A

adnexal mass, abdominal distension, bowel obstruction, pleural effusion.

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7
Q

What do you use to monitor response to therapy/relapse

A

CA 125 levels (not good for screening).

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8
Q

Most common ovarian neoplasm?

A

Serous Cystadenoma

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9
Q

What ovarian cancer is lined with fallopian tube–like epithelium. often bilateral

A

Serous Cystadenoma

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10
Q

What ovarian cancer is Multiloculated, large. Lined by mucus-secreting epithelium

A

Mutinous Cystadenoma

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11
Q

What ovarian cancer is Endometriosis (ectopic endometrial tissue) within ovary with cyst formation.

A

Endometrioma

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12
Q

What ovarian cancer presents with pelvic pain, dysmenorrhea, dyspareunia; symptoms may vary with menstrual cycle.

A

Endometrioma

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13
Q

What does the ovary look like in Endometrioma?

A

“Chocolate cyst”— endometrioma lled with dark, reddish-brown blood.

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14
Q

most common ovarian tumor in females 10–30 years old

A

Mature cystic teratoma (dermoid cyst)

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15
Q

What Ovarian Tumor is a Cystic mass containing elements from all 3 germ layers (eg, teeth, hair, sebum)

A

Mature cystic teratoma (dermoid cyst)

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16
Q

What is a strums ovary and how does it present?

A

A mono dermal form of a dermoid cyst with thyroid tissue, can present with hyperthyroidism

17
Q

Why can dermoid cysts be painful?

A

Can present with pain 2° to ovarian enlargement or torsion.

18
Q

What ovarian tumor Looks like bladder. Solid tumor that is pale yellow-tan and appears encapsulated.

A

Brenner Tumor

19
Q

What do you see on histo with a Brenner Tumor?

A

“Coffee bean” nuclei on H&E stain.

20
Q

What does a fibroma look like on histo?

A

Bundles of spindle-shaped fibroblasts

21
Q

What presents with a ‘pulling’ sensation in the groin?

A

Fibroma

22
Q

What is Meigs Syndrome triad?

A

triad of ovarian fibroma, ascites, hydrothorax.

23
Q

What benign ovarian tumor can secrete estrogen?

A

Thecoma

24
Q

How does a Thecoma present?

A

Usually presents as abnormal uterine bleeding in a postmenopausal woman.

25
Q

What is the analogous malignant ovarian tumor to a benign Thecoma?

A

Granulosa Cell Tumor (both secrete estrogen)

First Aid Reproductive Chapter (13 decks)

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