Pathology Flashcards

1
Q

What is the most common parasite of the bladder?

A

Schistosomiasis haematobium

Contracted in central Africa.

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2
Q

What is a long-term complication of schistosomiasis in the bladder?

A

Squamous cell carcinoma

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3
Q

Can catheters cause cancer?

A

Eventually, yes - they irritate the bladder wall.

Results in inflammation.

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4
Q

What is aseptic cystitis?

A

A condition characterised by persistent dysuria, despite negative culture results.

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5
Q

What is hydronephrosis?

A

Dilation of the urine collecting system.

The result of obstruction, leading to increased pressure within the system.

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6
Q

What is the biggest risk factor for bladder cancer?

A

Smoking

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7
Q

Is squamous epithelium present in the bladder?

A

No

Squamous cell carcinoma results from persistent inflammation producing metaplasia.

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8
Q

Does high-grade prostate cancer cause a high PSA?

A

No, as cells less likely to be that of the organ tissue.

Thus, digital rectal examination is essential if considering prostate cancer as a diagnosis.

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9
Q

What scoring system is used to grade prostate cancer?

A

Gleason grading system

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10
Q

Which age group typically presents with balanitis xerotic obliterans?

A

Young patients

Usually associated with phimosis/paraphimosis.

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11
Q

Which 2 strains of HPV are described as high-risk?

A

HPV16
HPV18

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12
Q

What is a hydrocele?

A

The accumulation of fluid around the testes.

Builds up between the 2 layers of the tunica vaginalis.

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13
Q

What is a varicocele?

A

Varicosities of the venous plexus of the testes.

Usually asymptomatic - feels like a ‘bag of worms’.

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14
Q

What is the most common form of testicular cancer?

A

Seminoma

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15
Q

What is the biggest risk factor for the development of testicular cancer?

A

An undescended testicle.

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16
Q

How are seminomas treated?

A

Radiotherapy

17
Q

How are non-seminomatous testicular cancers treated?

A

Chemotherapy

18
Q

Which form of testicular cancer is most likely to metastasise?

A

Non-seminomatous

19
Q

Raised LDH is associated with which form of testicular cancer?

A

Seminoma

20
Q
A