Patho 2- Multiple Sclerosis Flashcards
1
Q
Definition of multiple sclerosis
A
Chronic, demyelinating disease of CNS
Inflammatory process causing CNS degeneration
Severe neurological deficit
2
Q
Suspected triggers of MS
A
Infection Vaccination Pregnancy Trauma Emotional stress Environmental factors Viral factors Genetics Diet deficits
3
Q
Pathology of MS
A
Disruption of blood brain barrier
Leakage of inflammatory cells
Disruption of oligodendrocytes and myelin sheath
Disruption of nerve signals, rate of conduction slowed down
Plaques form throughout CNS
4
Q
Types of MS
A
Silent/Benign
Relapsing-Remitting
Secondary progressive
Primary progressive
5
Q
Signs and symptoms of MS
A
Visual problems Weakness Spasticity and hyperflexia decreased Ataxia and poor coordination Sensory loss Dizziness and poor balance Sphincter disturbance and sexual dysfunction Psychiatric and psychological disturbance Decreased intellectual function Fatigue
