PATH - Final Flashcards
When does Croup usually occur?
It usually appears after an episode of rhinorrhea, sore throat and fever
What is the body’s first line of defense?
A barrier formed by the skin and mucous membrane
What is the mechanical result of pleural effusion?
atelectasis
What is apoptosis?
Programmed cell death
Which antibody class is synthesized by the B cells, and insert into their own plasma membranes?
IgM
What is the most important factor in the gravity of a disease?
The strength of the patient’s immune system
Why do we need buffers
To maintain a level of pH
What is serous exudate?
Water blister
What does FAS stand for?
Fetal Alcohol Syndrome
What do you call it whenComplement activation is caused by innate immunity?
alternate pathway
What is a neutrophil?
The first WBC to arrive at a site of injury.
What primarily affects the nervous system, tissues that produces blood cells
Lead
What kind of pathogens arePseudomonas aeruginosa, Burkholderia cenocepacia, and Mycobacterium avium?
Opportunistic
What do we use to speed up the catabolism process?
Enzymes
What cells are part of adaptive immunity?
lymphocytes (B cells and T cells)
What are monocytes?
Immature cells that form in the blood
What do you call an acute airway obstruction caused by marked edema of the epiglottis and other supraglottic structures?
Epiglottitis
‘dysthesia’
no feeling
What isOrthopnoea?
Difficulty breathing while laying down
What level do Atoms interact to make compounds
Outer most orbit of the cloud
When does cancerous necrosis appear?
Tuberculosis
What is the process in which cells go to the harmed/ injured site?
Active migration
What are some examples ofpneumoconiosis?
- CWP (coal workerspneumoconiosis)
- Silicosis (inhalation of dust containing silica)
- Asbestosis (Asymptomatic and doesn’t appear for years)
What does ‘xanthos’ mean?
yellow
What are people with chronic bronchitis called?
Blue bloaters
What is the name of the cow plathmentic prathedosis?
Tiniasaginata
What cells are infected by HIV?
T lymphocytes (helper cells)
What are the 4 infectious agents?
- Virus
- Bacteria
- Fungal
- Parasite
What is Sarcoidosis?
Abnormal masses of consisting of inflamed tissue
How do pyrogens induce fever?
- promote prostaglandin production- prostaglandins reset the hypothalamic temperature to a higher temp
What is the most basic definition of an ionic bond?
When one electron is donated
Name members of the granulocyte family..
Neutrophils, basophils, eosinophils
What does the parasite,Trypanosoma Cruzy, cause?
Chagas disease
If one tissue is lacking oxygen, what is that tissue called?
Hypoxic
What do you call ahigh-pitched sound caused by obstruction of the air passageway?
Stridor
What are the effects of serotonin and histamine?
They cause:- temporary, rapid constriction of the smooth muscles of large vessel walls- Dialation of postcapillary venules - Increased vascular permeability from retraction of epithelial cells
What is the tool used by complement to kill bacteria
Perforin
What does the parasite,Giardia Lamblia, cause?
Giardiasis (Beaver fever) - in the duodendum
What is the single most common reason for cellular damage?
Hypoxia, lack of proper oxygen
What is one example of ionic bond
Sodium chloride
What do you call asubstance that the body recognizes as foreign and that can evoke an immune response?
Antigen
What is the general shape of an antibody?
Y
What cells produce antibodies?
B cells and plasma cells
‘coprolaia’
talking bullshit
What is a hematoma
A collection of blood in soft tissues or an enclosed space
What happens in apoptosis?
Necrosis of keratinocytes in which the nuclei of the necrotic cells dissolve and the cytoplasm shrinks, rounds up and is phagocytized by neighbouring healthy cells
What does the liver produce to help in the clotting system?
Prothrombin
What do you call aprotein produced by certain white blood cells (B lymphocytes, plasma cells) in response to an antigen
Antibody
When one epithelium is forced to change into another, what is the name of that change?
Metaplasia
DescribePseudomona
gram-negative rod
What do you call it when a cell loses its ability to change from one cell type to another/cellular differentiating
Anaplasia
What can block the synthesis of prostaglandins?
Aspirin and anti-inflammatories
What causes hypoxemia?
poor gas exchange
What doesEnterobius vermicularis or Oxyures (Pinworm) cause?
Enterobiasis (Deposit eggs on anal rim)
What is pathologic atrophy?
Occurs as a result of decreases in workload, pressure, use, blood supply, nutrition, hormonal stimulation, and nervous stimulation
What isCor Pulmonale?
enlargement of the right side of the heart as a result of lung disease (aka, pulmonary heart disease)
What do you call long chains of sugar
Polysaccharides
What is Autolysis?
Self breakdown
What is the function of natural antioxidants?
To inactivate free radicals
What is the most common catabolic reaction during the digestive process?
Hydrolysis
What are some signs and symptoms of lead poisoning?
high blood pressure joint and muscle pain headache abdominal pain memory & concentration
What is pulmonary capillary wedge pressure?
The pressure, at the capillary level, in the lungs.
What is Anoxia?
Total lack of oxygen
What isErysipelas?
Skin infection of the deep epidermis
Where is the fungal infection called,Candidemia, most commonly contracted?
In hospitals - found in the bloodstream
What germ produces typhoid fever?
Salmonella
If one epithelium perforates, what is the name of that change?
Hyperplasia
What are Leukotrienes?
Slow-reacting substances of anaphylaxis [SRS-A] – acidic, sulfur-containing lipids that produce effects similar to those of histamine
What are the two types ofAtelectasis?
- compression
* absorption
What are point mutations?
Changes in one or a few nucleotides
During sexual development, what is the name of that kind of change?
Hormonal hypertrophy
If a disease process rises the peripheral vascular resistance, what is the name of the results?
Secondary hypertension
What is the name of the limiting structure of a virus?
Capside
What isAtelectasis?
collapsed alveoli
What do you call a bacteria’s ability to strongly attack?
Virulence
What immune mechanism is inflammation part of?
innate immunity
What is a coup pattern?
contusion is underlying the area struck on the head
What isChylothorax?
Collection of milky, straw colored lymphatic liquid in pleural space
What kind of physical changes occur after one myocardium infarction?
Structural and functional
What does ‘erythoros’ mean?
Red
What is the name of the pleural effusion made of blood?
Hemothorax
If someone has an open pneumothorax of one lung, is that a critical injury?
no - because the person can still breathe with the other lung.
What iscryptogenic organizing pneumonia?
rare lung condition in which the bronchioles, alveoli and the walls of small bronchi become inflamed and plugged with connective tissue.
What is the name for a reduced blood supply
Ischemia
What is the name for an extreme laceration, often with a flap
Avulsion
what is the sinoquinone condition for bacteria to replicate?
Plasmatic iron
What is ‘Exudate’?
substances that defend the host against infection and facilitate tissue repair and healing
What is the classification of helminth?
Platyhelminths
What is atomic mass
The sum of protons and neutrons in the nucleus
What are some reasons for someone to develop DVT?
Trauma
venous stasis
damage
too many free radicals
What makes a fatty acid saturated or poly unsaturated?
Long chains of carbons have for valances of hydrogen – saturated, not filled with hydrogen is poly unsaturated
What do you callprotein toxins and enzymes produced and/or secreted from pathogenic bacteria?
Exotoxins
What does ‘neoplasm’ mean?
New growth
What is coagulative necrosis caused from?
hypoxia caused by severe ischemia or hypoxia caused by chemical injury
What do you call asubstance that the body recognizes as foreign and that can evoke an immune response?
Antigen
What happens when the administered oxygen you are giving to a patient is an inspired oxygen of about 50% for 48 hours?
The patient will die because you are oxidizing the patient
Define flail chest
Consecutive multiple fractures of the ribs
A chemical injury begins with what?
A biochemical interaction between a toxic substance and the cell’s plasma membrane; leading to increased permeability
What family do you borillia and micro plasm come from?
Bacteria
If bacteria affecting your releases exotoxins, what happens?
Cellular immune system
Humoral immune system
We produce antitoxins
What germ produces tuberculosis?
microbacteria
What is bleb?
Blister filled with serous fluid (in lung)
What does resolution mean, as it relates to tissue?
tissue repair and regeneration
What isCompression Atelectasis?
collapsed alveoli due to external pressure (ex, tumor)
When a bleb ruptures, in lungs what is it called?
Pneumothorax
When is one element in it
When it is following the rule of octet
What are three types of reactions
Synthesis reaction
Decomposition reaction
Exchange reaction
What cells become infected in HIV?
helper T cells
What are the 2 triggers for hypertrophy?
Mechanical signals - Ex: expansion due to weightlifting.Trophic signals - growth factors, hormones and vasoactive agents (Ex, if you remove 1 kidney, the other would increase in size)
What are the 4 phases of tumor spread?
- tranformation
- growth
- local invasion
- distant metastasis
What does ‘penia’ mean?
lack of sufficient amount
What do you call it when cells change from one cell to another?
Metaplasia
What is adipocyte?
Fat cell
What does ‘In situ’ mean?
in that place/position
What is the name of the process of breaking down to make something different?
Lysis (Catabolism)
What is helminth?
parasite
What is caseous necrosis caused from?
Caused by tuberculosis pulmonary infection - The dead cells disintegrate but the debris is not completely digested by the hydrolases
How long does chronic inflammation last?
Longer than 2 weeks
What do you call it when cells increase in number
Hyperplasia
What do you call it when cells are marked for destruction by phagocytes?
Opsonization
What is a neoplasm?
Tumor
What do you call it when the HIV virus becomes active and begins to spread,destroying the helper Tcellsin the process?
lysogenic cycle
Which antibody is found at heightened levels in someone with asthma?
IgE
True or False: Acute alcoholism induces reversible gastric and hepatic changes?
TRUE
What are Interferons?
One of the body’s defenses against viral infection
What is Adipocerae?
a grayish waxy substance formed by the decomposition of soft tissue in dead bodies subjected to moisture
Give an example of physiologic atrophy
As a fetus grows in utero, the tail eventually disappears.
What is balano?
tip of penis
What is the definition of pneumoconiosis?
result of chronic inhalation of nanoparticulate
What is the clotting system?
aka - coagulationPlasma protein system that forms a fibrous meshwork at the inflamed site to trap exudates, microorganisms and foreign bodies
What does ‘plathos’ mean?
flat
True or False: Platelets do not have a nucleus?
TRUE
What is Cellulitis?
Skin infection involving inflammation of the connective tissue, and severe inflammation of the dermis and subcutaneous layer of skin.
What is the structure of Prostaglandins?
Long chain unsaturated fatty acids
What is an example of pathologic hyperplasia?
Pathologic hyperplasia of the endometrium which causes excessive menstrual bleeding
What isDyspnea?
shortness of breath
What isCarcinoma in situ?
Preinvasive cancer of the epithelial or glandular tissue that hasn’t broken through the basement membrane or invaded surrounding area
What kind of cancer is most commonly a result of asbestos exposure?
mesothelioma
What are the possible outcomes of developing a lung abscess
Plural infusion; pyothorax; leaking of pus that goes to the lumen
What are phagocytes called in the nervous system?
microglia
What is prinzmental angina?
Coronary vasospasm
If someone has one abscess in one lung, where did that problem come from?
Bacterial pneumonia
What are 3 examples of Acute lung injury?
- Pulmonary edema
- Acute respiratory distress syndrome
- acute interstitial pneumonia
What are 3 types ofemphysema?
- Centriacinaremphysema
- Panacinaremphysema
- Paraseptalemphysema
What is the name of community-acquired pneumonia?
streptococcus pneumoniae
What would cause progressive fever, and worsening harshness of the voice, with increasing dyspnea (difficulty to breathe)?
diphtheria
How does a natural killer cell kill?
Lyses
What is an example of hormonal hyperplasia?
When breasts grow due to pregnancy
Where are lymphocytes made?
- bone marrow- thymus- lymph nodes- spleen
What is Löffler’ssyndrome?
larvae in the lungs from parasite
What are the 3 factors of thevirchow triad?
- stasis (stability)
- vessel wall injury
- hypercoagulability
What isAngiogenesis?
formation of new blood vessels
What do you do to resynthesized a molecule that has been broken apart using hydrolases?
DeHydro synthesis
What isAbsorption Atelectasis?
collapsed alveoli - caused by continued absorption of remaining O2 in alveoli while the bronchi is blocked
What is the name of bacteria that develops into colonies that look like Indian rows?
Streptococcus
Name the bacteria, when taken from cultureand placed under the microscope, look like coffee seeds?
- Diplococcis
What is vomica?
coughing up the contents of a perforated abscess
What isParoxysmal nocturnal dyspnea?
Sudden difficulty breathing at night
Why is sudden hypoxia worse than gradual hypoxia?
Gradual allows for adaptation
What is bacterial vaginosis?
A group of vaginal diseases caused by an imbalance of natural bacterial flora.
Where oxures lay their eggs?
Anal rim
What is bacterial pneumonia?
infection of the lungs
What is an Epidural Hematoma?
blood between the inner surface of the skull and the dura
What is one example of nontraditional risk of pulmonary artery disease
Chronic infection
What is the name of the negative poll?
Ano, catho
Definition of compound
Combination of two or more atoms that are different
What isDysphagia?
difficulty swallowing
How does hypercapnic respiratory failure happen?
Inadequate ventilation
What is the name of the acute infection of the lower respiratory tract with parenchyma and bronchus?
pneumonia
What happens when a muscle increases its workload?
Hypertrophy
What is the general name of infectious organisms?
Bacteria
Virus
Fungi
What are mast cells?
They activate the inflammation response through degranulation and synthesis
What is the result of collapse bronchi?
They do not collapse
What is radiation pneumonia?
Inflammation of the lungs from radiation therapy of the chest
What does Metastasis mean?
Spreading / traveling
What is converted into t cells in the thymus?
Lymphocytes
What is pathologic hyperplasia?
Abnormally fast increase of normal cells.
What is the name of a malignancy of the peritoneum?
Mesothelioma
True or False: Ischemia is the most common cause of hypoxia?
TRUE
The parasite,Plasmodium spp. (Hematic), can cause what?
malaria
Where do mast cells come from?
bone marrow
What is another name for a scrape
Abrasion
What istuberculosis?
An infection that can destroy the lung tissue
What condition ischaracterized by exudativepharyngitis, fever, and bright-red exanthema?
Scarlette fever
What is the body’s third line of defense?
adaptive immunity
What are 3 types of hyperplasia?
compensatoryhormonalpathologic
What is Hypoxemia?
Low oxygen in the blood
What substances produce pain?
Kinase and prostaglandins
What isHyperpnoea?
- increased respiratory rate
* abnormal breathing pattern
What is an example of compensatory hyperplasia?
If you remove part of the liver, more liver cells will regenerate
What is the replacement of 1 mature cell type by another less mature cell type?
Metaplasia
From the hydrogen point of you, what are acids
Hydrogen ion donor’s
what are phagocytes called in the liver?
kupffer
What is another name for ASA?
Aspirin
What is more dangerous, sudden or progressive hypoxia
Sudden, because your body does not have time to adapt
What do pyrogens released from damaged tissue, or introduced into the body trigger?
fever
What is the rule for something to be organic or inorganic
Organic is carbon to carbon, or carbon to hydrogen
What is leukopenia?
Reduced white blood cells
What are lymphomas?
Cancer of the lymphatic tissue
What is the average amount of water in a human body?
55%
Why is the hydrogen Atom so reactive
It is seeking
What is metaplasia?
What one mature cell is replaced by a less mature cell
What doesIdiopathic mean?
No known cause
What are the six types of necrosis
Coagulative Liquefactive Caseous Fat Gangrenous - Dry gangrene - Wet gangrene - gas gangrene Apoptosis
What is the name of the biochemical and cellular changes that occur in an attacked tissue?
Inflammation
What is the name for the breaking of blood vessels
Contusion
What is the name for total lack of O2
Anoxia
What isHemothorax?
Blood in pleural space
How does carbon monoxide affect the body?
Binds to hemoglobin and takes the place of the oxygen moleculeDirectly interfere with cellular respiration
What isleukemia?
Cancer of the blood-forming cells
How do mast cells work?
They move through the bloodstream and mature in tissue.
What isDiffuse alveolar damage (DAD)?
Injury to the gas exchange surfaces
What is an abscess of the lung?
A condition caused after pulmonary disease/injury
What isEmpyema?
Infected pleural effusion; pus
What does a Eosinophile chemotactic factor do?
attracts eosinophils to the inflamed site
‘stetho’
chest
What isOdynophagia?
Painful swallowing
What factor favors disassociation of oxygen?
- Increased temperature
- reduce pH
- presence of a fetus
What binds to hemoglobin and takes the place of the oxygen molecule
Carbon monoxide
DefineFlail chest
Floating piece of chest wall due to multiple consecutive rib double fractures
What is a counter coup?
cerebral contusion is seen in the area opposite the location of the injury
What is an element made of?
same atoms
What would be the purpose of the mutation of tumor-suppressor genes?
allows unregulated cellular growth (aka, cancer)
How can acute alcoholism affect the body?
Can cause reversible changes to the stomach:- inflammation- deposit fat- liver enlargement- interruption of microtubular transport of proteins and their secretion- increased intracellular water- depression of fatty acid oxidation in the mitochondria- increased reactive oxygen species and acute liver cell necrosis
What has decreased the incidence rate of Epiglottitis?
HIB vaccine
How do you know, during an asthmatic crisis, that respiratory failure is imminent?
When the partial pressure of carbon dioxide is continuously rising
When B cells differentiate, what types of cells do they clone?
plasmic cells and memory cells
What are 3 Systemic Manifestations of Acute Inflammation?
1) Fever – beneficial to kill bacteria2) Increase in circulating WBC’s3) Increase in circulating plasma proteins
What is dysplasia?
atypical cells - Often encountered in epithelial tissue of the cervix and respiratory tract and often are found adjacent to cancerous cells
What does ‘plathominth’ mean?
flat worm
What happens if the number of electrons in the shell is less than that of the number of protons?
Unstable
‘cephalea’
headache