Path antibodies Flashcards
1
Q
Hashimotos + what the recipients of antibodies normally do
A
anti thyroperoxidase
anti thyroglobulin
Thyroglobulin is the protein made when TSH is stimulated, it is then joined with tyrosine and two of these molecules form di or mono iodothyronine
thyroperoxdiase converts iodide into iodine and attaches iodine to thyroglobulin to make T3 and T4
2
Q
Graves
A
Anti TSH receptor antibody
3
Q
Myasthenia gravis
A
Anti Ach receptor
4
Q
PBC
A
anti mitochondrial Ab - causes T cell destruction of bile ducts
5
Q
Pernicious anaemia
A
Anti gastric parietal cells (main one)
Anti intrinsic factor
6
Q
CREST
A
Anti CENTROMERE
7
Q
RA
A
Anti-ccp
