GI disease PATH

Question 1

What is Barrett’s

Answer 1

Simple columnar to squamous columnar (SCJ moves upwards in 10 percent of people with GORD)

Question 2

Barretts predisposes to what type of cancer

Answer 2

Adenocarcinoma

Question 3

Name another type of oesophageal cancer

Answer 3

Squamous cell oesophageal cancer

Question 4

Risk factors for Squamous cell oesophageal cancer

Answer 4

Plummer Vinson syndrome - web like structures in the oesophagus
Achalasia of cardia - oesophageal nerve damage

Question 5

Presence of what cells suggests intestinal metaplasia in the oesophagus from GORD?

Answer 5

Goblet cells (usually not in squamous cells but are in columnar cells)

Question 6

H pylori can give rise to what type of gastric cancer?

Answer 6

Mucosa associated lymphoid Tissue lymphoma aka B cell lymphoma

Question 7

Gastric cancer another type

Answer 7

Adenocarcinoma

Question 8

Goblet cells in the stomach mean

Answer 8

Intestinal metaplasia

Question 9

How do you treat MALT h pylori

Answer 9

Triple therapy - PPI, clari and amoxicillin

Question 10

Epigastric pain, worse at night, relieved by food and milk

Answer 10

Duodenal cancer

Question 11

Histology of coeliac disease

Answer 11

Increased villous atrophy

Question 12

Coeliac disease can give rise to what type of cancer

Answer 12

EATL

Question 13

What happens to the body of the stomach in a patient with pernicious anaemia?

Answer 13

Chronic gastritis and atrophy

Question 14

Childhood renal tumour presenting as an abdominal mass

Answer 14

Wilm’s tumour/nephroblastoma

Question 15

What kind of pancreatic pathology can you get following pancreatitis?

Answer 15

Pancreatic pseudocyst

Question 16

What is the most common type of pancreatic cancer?

Answer 16

Ductal adenocarcinoma of the pancreas