passmed Flashcards
what is cimetidine?
H2 receptor antagonist (inhibits stomach acid production)
the p’s pf raised prolactin?
pregnancy prolactinoma physiological PCOS primary hypothyroidism phenothiazines (metaclPramide, domPeridone)
HbA1c - does it have a place in diagnosis of type 1 diabetes?
no
what diabetic medication must be avoided in patient with history of heart failure?
pioglitazone
what do DDP4 inhibitors do to weight?
weight neutral
give an example of a DPP4 inhibitor?
sitagliptin (griffin) (saxophone)
pioglitazone side effects?
weight gain
liver impairment
increased fracture risk
causes fluid retention (can’t use in heart failure)
when is piogitazone contraindicated?
in heart failure - causes fluid retention
most common side effect in sufonylureas?
weight gain (fat bride)
other side effects of sufonylureas?
SIADH
bone marrow suppression
liver damage
peripheral neuropathy
what is a known complication of carbimazole
agranulocytosis
what would a patient develop with ahranulocytosis?
sore throat or fever
which drugs may reduce hyperglycaemic awareness?
beta blockers