final Flashcards
1
Q
1/2 dose of metformin if eGFR is ?
A
between 30 and 45
2
Q
which drug causes secretion of insulin in a glucose independent manner?
A
SU
3
Q
what drug can cause osteoporosis and fracture?
A
pioglitazone
4
Q
pioglitazone contraindicated if?
A
osteoperosis, over 65, CCF
5
Q
name an incretin analogue
A
extenatide
6
Q
do incretin analogues cause weight gain or weight loss
A
weight loss
7
Q
incretin analogues - risk ?
A
pancreatitis
pancreatic cancer
8
Q
name a DDP4 inhibitor?
A
stitagliptin
9
Q
what does DDP4 break down?
A
incretin
10
Q
what can DDP4 inhibitors cause?
A
nausea, pancreatitis
11
Q
name an alpha glucosidase inhibitor?
A
acarbose
12
Q
what is the mechanism of action of glycosidase inhibitor?
A
prevents carbohydrate breakdown in the gut
13
Q
side effects of acarbose
A
wind, diarrhoea
abdominal pain and bloating
