Hormones and carrier proteins

Question 1

t3 and t4 solubility in plasma?

Answer 1

relatively insoluble

Question 2

rate limiting step in hormone production?

Answer 2

cholesterol to pregnenolone

Question 3

ACTH and ADH are made from ?

Answer 3

larger precursor proteins

Question 4

how does insulin lower plasma glucose?

Answer 4

inhibits glyconeogenesis and glycogenolysis

Question 5

what does adrenaline do in terms of glucose and muscle and adipose?

Answer 5

causes uptake of glucose into muscle and fat

Question 6

how are amines made/stored?

Answer 6

they are pre synthesised

Question 7

how are amines transported?

Answer 7

free in plasma, they are hydrophilic

Question 8

how are amines released?

Answer 8

released in response to stimuli by ca dependant exocytosis

Question 9

peptides and proteins. how are they released?

Answer 9

released in response to stimuli by ca dependant exocytosis

Question 10

what does albumin bind?

Answer 10

many steroids and thyroxin

Question 11

only hormone in which form can cross the capillary wall to activate receptors in target tissues

Answer 11

free hormone

Question 12

how is hormone eliminated from body?

Answer 12

Elimination of hormone occurs by several routes. Most importantly metabolism by liver and excretion by the kidneys

Question 13

what are the three types of hormone receptor?

Answer 13

G protein coupled, receptor kinase and nuclear receptors (class 1, 2 and 3)