adrenal physiology Flashcards

1
Q

how can the adrenal gland be divided into two?

A

adrenal medulla and adrenal cortex

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2
Q

which part of the adrenal gland is directly connected to sympathetic nervous system?

A

medulla

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3
Q

what does the renal medulla secrete?

A

adrenaline and non adrenaline (catecholamines)

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4
Q

from superficial to deep - zones of the cortex?

A

Zona
Glomerulosa
Fasciculata
Reticularis

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5
Q

which zone secretes aldosterone?

A

glomerulosa

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6
Q

what type of substance is aldosterone?

A

mineralocorticoid

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7
Q

what are the two types of corticosteroid?

A

mineralocorticoid and glucocorticoid

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8
Q

what does aldosterone do to sodium, chloride and potassium ?

A

causes retention of sodium and chloride and excretion of potassium (retain Na, rid of Ka)

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9
Q

aldoserone and sweating

A

increased aldosterone causes sweating

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10
Q

lack of aldosterone - what would values of Na and K be like?

A

high Ka, low Na

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11
Q

what do glucocorticoids stimulate?

A

gluconeogenesis (which is why diabetes is a known complication)

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12
Q

cortisol effect on glucose?

A

causes an increase in circulating glucose

but a decreased utilization of circulating glucose

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13
Q

what is the effect of stress on ACTH secretion ?

A

stress increases ACTH

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14
Q

naturally, when is highest ACTH secretion?

A

morning, circadian rhythm

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15
Q

what part of the pituitary is ACTH released from

A

anterior pituitary

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16
Q

synthetic examples of cortisol?

A

prednisolone and dexamethasone

17
Q

why would you get depression in steroid use

A

disruption in circadian rhythm of steroids

18
Q

which cells release NA and A in renal medulla?

A

chromaffin cells