neuropathies Flashcards

1
Q

the 4 types of nephropathies?

A

peripheral, focal, autonomic and proximal

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2
Q

which one responsible for changes in bladder, bowel, erectile problems, sweating, hr, BP

A

autonomic

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3
Q

which is a sudden weakness in one nerve or nerve group?

A

focal neuropathy

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4
Q

which type f neuropathy is carpal tunnel?

A

focal

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5
Q

which type of neuropathy is bells palsy?

A

focal

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6
Q

what sort of symptoms can you get in a peripheral neuropathy?

A

burning, stinging, numbers, insensitivity, sharp pains, cramps, sensitivity to touch, loss of balance/co ordination (CHECK SOLES)

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7
Q

three complications of peripheral neuropathy? (think feet)

A

charcot foot, painless trauma (nail through foot) and ulcer

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8
Q

pain in thighs/hips/buttocks leading to weakness in legs (amyotrophy)

A

proximal neuropathy

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9
Q

how can you treat pain in neuropathy?

A

amitryptaline

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10
Q

focal neuropathies appear suddenly and affect specific nerves. where do you most often get them?

A

head, torso, leg

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11
Q

what is gastroparesis?

A

slow gastric emptying

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12
Q

most common symptoms of oesophageal nerve damage?

A

dysphagia

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13
Q

example of 2 pro motility drugs?

A

metoclopramide and domperidone

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14
Q

what ratio can you use to screen for diabetic kidney disease?

A

urinary creatinine ratio (ACR)

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15
Q

what should blood pressure be maintained at in all patients with diabetes?

A

less than 130/80

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16
Q

what should patients with microalbuminuria or proteinuria be commenced on?

A

an ACE inhibitor or ARB

17
Q

acute hyperglycaemia can do what to vision?

A

blurring

18
Q

what other eye conditions are more common in diabetes?

A

glaucoma and cataract

19
Q

stages of retinopathy?

A

Mild, moderate and severe NON PROLIFERATIVE retinopathy. and proliferative retinopathy

20
Q

how is proliferative diabetic retinopathy defined?

A

neovascularization. Greater potential for serious visual consequences

21
Q

how do you get hard exudates?

A

get fluid deposition under the macula. Resolution of this fluid can leave behind hard exudates, like a receding river after a flood

22
Q

you get loss of which type of cells in the capillaries?

A

pericytes

23
Q

as npdr progresses, the affected vessels may become obstructed. this obstruction leads to infarction of the nerve fibre layer. This results in?

A

fluffy white patches known as cotton wool spots

24
Q

what does VEGF stimulate?

A

growth of new blood vessels

25
Q

what is wrong with the new blood vessels?

A

they are leaky, fragile and misdirected. they can grow out of the retina and in to the vitreous