part 12

Question 1

thickening of vessel membranes in capillaries and arterioles

Answer 1

microvascular angiopathy

Question 2

What are the 3 types of microvascular angiopathy?

Answer 2

• retinopathy
• nephropathy
• dermopathy

Question 3

What is different about macro and microvascular angiopathy?

Answer 3

microvascular angiopathy (retinopathy, nephropathy, and dermopathy) are specific to diabetes.

Question 4

When do microvascular angiopathy problems appear?

Answer 4

10-20 years after diagnosis

Question 5

microvascular damage to retina

Answer 5

diabetic retinopathy

Question 6

What is the most common cause of new cases of adult blindness?

Answer 6

diabetic retinopathy

Question 7

What type of diabetic retinopathy is more sever and which is more common?

Answer 7

• nonproliferative: more common

- proliferative: more severe

Question 8

partial occlusion of small blood vessels in retina causes microaneurysms

Answer 8

nonproliferative diabetic retinopathy

Question 9

• involves retina and vitreous humor
• new blood vessels formed (neovascularization): very fragile and bleeds easily
• can cause retinal detachment

Answer 9

proliferative diabetic retinopathy

Question 10

How often should diabetic pts get eye examinations?

Answer 10

annual with dilation

Question 11

What are the treatments for diabetic retinopathy?

Answer 11

• Laser photocoagulation (destroys ischemic areas of retina)
• vitrectomy (aspiration of blood, membrane, and fibers inside the eye)
• drugs to block action of vascular endothelial growth factor (VEGF)