Parasympatholic Flashcards
1
Q
Atropine:
- Functional Class
A
- Parasympatholytic (inhibts)
2
Q
Atropine:
- Mechanism of action
A
- Inhibits parasympathetic stimulation by blocking muscarinic receptors Ach.
- Blocks Vagal impulses to the heart which accelerates SA discharge.
- Enhances conduction through AV junction and increases CO.
- Also a potent bronchodilator if bronchoconstriction is caused by increased parasympathetic stimulation.
3
Q
Atropine:
- Indications
A
- Symptomatic bradycardia
- Organophosphate/nerve agent poisoning
4
Q
Atropine:
- Contraindications
A
- None in emergency setting.
5
Q
Atropine:
- Dosage/Route: Symptomatic bradycardia
A
- Adult: 0.5 mg IVP q 3-5 min max of 0.04 mg/kg (normally 3 mg)
- Pedi: 0.02 mg/kg IVP/IO (minimum single dose is 0.1 mg, max 0.5 mg) Repeat once if needed.
6
Q
Atropine:
- Dosage/Route: Organophosphate poisoning
A
- Adult: 2 mg IVP q 5 min prn
- Pedi: 0.05-0.1 mg/kg IV/IM (minimum dose of 0.1 mg and max dose of 0.5 mg) repeat q 2-5 min prn.
7
Q
Ipratropium bromide (Atrovent)
- Functional Class
A
- Parasympatholyic Bronchodilator
8
Q
Ipratropium bromide (Atrovent
- Mechanism of Action
A
- Acts directly on smooth muscle bronchial tree.
- Inhibts Ache at bronchial smooth muscle receptor sites.
9
Q
Ipratropium bromide (Atrovent
- Indications
A
- Bronchospasm
- Reversible obstructive airway disease
10
Q
Ipratropium bromide (Atrovent
- Contraindications
A
- Hypersensitivity to ipratropium, atropine, soya lecithin and peanut oil
11
Q
Ipratropium bromide (Atrovent
- Precautions
A
- Pregnancy and Lactation
12
Q
Ipratropium bromide (Atroven)
- Side Effects
A
- Worsening Bronchospasm
- N/V
- Cramps
- Dry mouth
- Blurred Vision
- drying of bronchial secretions
- cough
- epistaxis
13
Q
Ipratropium bromide (Atrovent
- Interactions
A
- None
14
Q
Ipratropium bromide (Atrovent)
- Dosage/Route:
A
- Adult: 0.5 mg (500 mcg) in 2.5-3 mL is of NS, neb q 6 hrs
- Pedi: 0.125-0.25 mg (125-250 mcg) in 3.5-3 mL NS, neb q 6 hrs
