Antipyretic Flashcards
0
Q
Acetaminophen ( Tylenol, APAP):
- Mechanism of Action
A
- Produces analgesia by elevating pain threshold.
- May block pain impulses by inhibiting prostaglandins in CNS.
- Does not possess any anti-inflammatory or anti platelet properties.
1
Q
Acetaminophen ( Tylenol, APAP):
- Functional Class
A
- Antipyretic
2
Q
Acetaminophen ( Tylenol, APAP):
- Indications
A
- Fever
3
Q
Acetaminophen ( Tylenol, APAP):
- Contraindications
A
- Hypersensitivity to acetaminophen or phenacetin.
4
Q
Acetaminophen ( Tylenol, APAP):
- Precautions
A
- Anemia
- Hepatic/Renal disease
- Alcoholism
5
Q
Acetaminophen ( Tylenol, APAP):
- Side Effects
A
- N/V
- Dizz
- Hepatotoxicity
- Renal Failure
- Hypoglycemia
6
Q
Acetaminophen ( Tylenol, APAP):
- Interactions
A
- Increased chance of Hepatotoxicity w/ chronic use, or w/ alcohol, rifampin, carbamazepine, or barbiturates.
7
Q
Acetaminophen ( Tylenol, APAP):
- Dosage/Route
A
- Adult: 325-650 mg PO/PR q 4-6 hrs
- Pedi: 15 mg/kg PO/PR q 4-6 hrs
8
Q
Ibuprofen (Advil, Motrin, Nuprin):
- Functional Class:
A
- Antipyretic
- Analgesic
- NSAID
9
Q
Ibuprofen (Advil, Motrin, Nuprin):
- Mechanism of Action:
A
- Inhibits Cyclooxygenase (COX) decreasing production of prostaglandins thurs decreasing sensation, fever, and inflammation.
10
Q
Ibuprofen (Advil, Motrin, Nuprin):
- Indication:
A
- Fever
11
Q
Ibuprofen (Advil, Motrin, Nuprin):
- Contraindications:
A
- Hypersensitivity
- Children <6 months old
- GI intolerance such as colitis
12
Q
Ibuprofen (Advil, Motrin, Nuprin):
- Precautions:
A
- Pregnancy
- Peptic Ulcer Disease
- Pulm Edema
- HTN
13
Q
Ibuprofen (Advil, Motrin, Nuprin):
- Side Effects
A
- N/D
- Abd pain
- Dizz
- Tinnitis
14
Q
Ibuprofen (Advil, Motrin, Nuprin):
- Interactions
A
- Reduce the effectiveness of loop diuretic and ACE-inhibitors.
- Increases hemorrhage potential when given w/ ASA
