Other Flashcards

1
Q

Aspirin

  • Functional Class
A
  • Salicylate
  • Analgesic
  • Antiplatelet
  • Antipyretic
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2
Q

Aspirin

  • Mechanism of Action
A
  • Blocks production of cyclooxygenase (COX), the precursor to Thromboxane A2 (Induces platelet aggregation).
  • Anti-inflammatory properties from blocking prostaglandin synthesis, which contributes to analgesic effects.
  • Also reduces fever by central-mediated peripheral vasodilation and sweat.
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3
Q

Aspirin

  • Indications
A
  • Suspected MI
  • C/P
  • ACS
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4
Q

Aspirin

  • Contraindications
A
  • Hypersensitivity
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5
Q

Aspirin

  • Precautions
A
  • Peptic Ulcer Disease

- Asthma

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6
Q

Aspirin

  • Side Effects
A
- OD may result in toxicity w/ 
> Dizz, N/V
> Thrombocytopenia
> Easy Bruising
> Metabolic Acidosis
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7
Q

Aspirin

  • Interactions
A
  • Incompatible with uricosuric agents

- Anticoagulations increase risk of bleeding

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8
Q

Aspirin

  • Dosage/Route
A
  • 160-325mg PO Tablets
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9
Q

Dextrose

  • Functional Class
A
  • Carbohydrate
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10
Q

Dextrose

  • Mechanism of Action
A
  • Principle form of glucose used by the body to create energy
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11
Q

Dextrose

  • Indications
A
  • Hypoglycemia
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12
Q

Dextrose

  • Contraindications
A
  • None with documented hypoglycemia
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13
Q

Dextrose

  • Precautions
A
  • Caution with ICP as added glucose may worsen cerebral edema.
  • Monitor glucose before and after administration
  • Local venous irritation
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14
Q

Dextrose

  • Side Effects
A
  • Tissue Necrosis
  • Phlebitis
  • Pain at injection site
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15
Q

Dextrose

  • Interactions
A
  • None
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16
Q

Dextrose

  • Dosage/Route
A
  • Adult: 25g of 50% solution IVP prn

- Pedi: 0.5g/kg IVP/IO of 25% solution, <10kg use 10% solution

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17
Q

Diphenhydramine (Benedryl)

  • Functional Class
A
  • Antihistamine
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18
Q

Diphenhydramine (Benedryl)

  • Mechanism of Action
A
  • Blocks H1 (Bronchoconstriction, periph vasodilation) and Acetylcholine (Anticholinergic) receptors sites
  • Reverse dsytonic reactions caused by anti-psychotic meds that block histamine receptors
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19
Q

Diphenhydramine (Benedryl)

  • Indications
A
  • Anaphylaxis
  • Moderate-severe allergic reactions
  • Acute extrapyramidal (dsytonic) reactions
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20
Q

Diphenhydramine (Benedryl)

  • Contraindications
A
  • Hypersensitivity
  • Newborns
  • Nursing Mothers
21
Q

Diphenhydramine (Benedryl)

  • Precautions
A
  • Not the primary drug for severe allergic reactions or anaphylaxis
  • Cautions w/ narrow angle glaucoma
22
Q

Diphenhydramine (Benedryl)

  • Side Effects
A
  • Hypotension
  • N/V, dry mouth
  • Tachycardia
  • Bradycardia
  • Sedation
  • Palpitations
  • Disturbed coordination
23
Q

Diphenhydramine (Benedryl)

  • Interactions
A
  • Potentiated by other CNS depressants, antihistamines, narcs, and alcohol
  • MAOI’s may prolong or intensify anticholinergic effects
24
Q

Diphenhydramine (Benedryl)

  • Dosage/Route
A
  • Adult: 25-50mg IVP/MI q 6-8 hrs

- Pedi: 1mg/kg IV/IO, Max single dose of 50mg, q 6-8 hrs

25
Furosemide (Lasix) - Functional Class
- Loop Diuretic
26
Furosemide (Lasix) - Mechanism of Action
- Rapid-acting loop diuretic - Inhibits Na+ and Chl- reabsorbtion in the loop of henle - Has vasodilatory properties
27
Furosemide (Lasix) - Indications
- CHF | - Acute Pulmonary Edema
28
Furosemide (Lasix) - Contraindications
- Hypersensitivity - Hypotension - Dehydration - Electrolyte Depletion
29
Furosemide (Lasix) - Precaution
- Use in preg pts should be limited to life-threatening emergencies, can cause fetal abnormalities - Protect form light - Renal/hepatic insufficiencies
30
Furosemide (Lasix) - Side Effects
- Hypotension - C/P - Hypochloremia/kalemia/natremia/calcemia/magnesemia - Hyperglycemia - Ototoxicity - Dizz, N/V, Dry mouth - Tinnitus with fast push
31
Furosemide (Lasix) - Interactions
- Digitalis and lithium toxicity
32
Furosemide (Lasix) - Dosage/Route
- 0.5-1mg/kg slow IVP (1-2 min) | - General Dosing: 40-120 mg Slow IVP
33
Haloperidol (Haldol) - Functional Class
- Antipsychotic
34
Haloperidol (Haldol) - Mechanism of Action
- Sedation by decreasing nerve impluse transmission by blocking dopamine and serotonin receptors of the CNS
35
Haloperidol (Haldol) - Indications
- Behavioral emergencies w/ violent tendencies, including suicide
36
Haloperidol (Haldol) - Contraindications
- Hypersensitivity - Children - Alcohol Intoxication - Coma
37
Haloperidol (Haldol) - Precautions
- Hx of seizures and parkinsons disease
38
Haloperidol (Haldol) - Side Effects
- Dsytonic reactions - Sedation - Dizz, N/V, Dry mouth - Hypotension - Constipation - Decreases seizure threshold
39
Haloperidol (Haldol) - Interactions
- Increased sedation with narc agonists, benzos, TCA's, alcohol and antihistamines
40
Haloperidol (Haldol) - Dosage/Route
- Adult: 5mg IM, may repeat once in 5 min.
41
Methylprednisone (Solu-Medrol) - Functional Class
- Corticosteroid
42
Methylprednisone (Solu-Medrol) - Mechanism of Action
- Intermediate-acting, synthetic adrenal corticosteroid - Decreases inflammation by reversing cap permeability - This suppresses migration of leukocytes and fibroblast to the site of the injury - Stabilizes Lysosomes
43
Methylprednisone (Solu-Medrol) - Indications
- Severe Asthma - Anaphylaxis - COPD
44
Methylprednisone (Solu-Medrol) - Contraindications
- None in the management of anaphylaxis
45
Methylprednisone (Solu-Medrol) - Precautions
- Peptic Ulcer Disease - CHF - TB
46
Methylprednisone (Solu-Medrol) - Side Effects
- Hypotension - CHF - Hyperglycemia - Hypokalemia - Circulatory Collapse - CNS Depression - H/A, N/V, delayed wound healing
47
Methylprednisone (Solu-Medrol) - Interactions
- Caution w/ salicylates, phenytoin, rifampin, theophylline, furosemide, and thiazide diuretics
48
Methylprednisone (Solu-Medrol) - Dosage/Route
- Adult: 125-250mg IVP/IM | - Pedi: 1mg/kg IVP